Ana Isabel Pinto

Proteomic Profiling Identifies MARCO in Extracellular Vesicles, as a Potential Biomarker for Leishmaniasis in HIV Co-Infection

Inês Costa, Ana Isabel Pinto, Sofia Esteves, Cátia Caldas et autres

Leishmania is an intracellular protozoan parasite that causes leishmaniasis, a disease prevalent in 97 countries. Co-infection with HIV increases susceptibility to visceral leishmaniasis (VL), accelerating HIV’s progression to AIDS. Managing VL in HIV-infected individuals is challenging due to atypical presentations and limited …

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Leishmania and HIV co-infection: first naturally Leishmania strain presenting decreased susceptibility to miltefosine, recovered from a patient in Portugal

Ana Isabel Pinto, Cátia Caldas, Nuno Santarém, Sara Luelmo et autres

In Europe, up to 70% of visceral leishmaniasis (VL) cases occurring in adults living with HIV. People living with HIV with VL co-infection often display persistent parasitemia, requiring chronic intermittent anti-Leishmania therapies. Consequently, frequent VL relapses and higher mortality rates are common …

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Visceral Dissemination of Mucocutaneous Leishmaniasis in a Kidney Transplant Recipient

Nídia Marques, Manuela Bustorff, Anabela Cordeiro‐da‐Silva, Ana Isabel Pinto et autres

Intracellular protozoan of the genus Leishmania, endemic in the Mediterranean basin, are the cause of cutaneous (CL), mucocutaneous (MCL), and visceral leishmaniasis (VL). A 75-year-old woman was admitted nine years after a second kidney transplant (KT), due to persistent pancytopenia and fever. …

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Chronic infection with Leishmania donovani impacts on bone marrow haematopoiesis

Ana Isabel Pinto, Natalie Brown, Olivier Preham, Jane E. Dalton et autres