Giulia Brizzi

A Multinational Randomized Trial of Mega-Dose Esomeprazole as Anti-Inflammatory Agent in Sepsis

Giacomo Monti, Sonia Carta, Yuki Kotani, Andrea Bruni et autres

OBJECTIVES: Proton pump inhibitors have dose-dependent immunomodulatory effects. We tested the hypothesis that mega-dose esomeprazole therapy would reduce organ dysfunction in patients with sepsis or septic shock. DESIGN: A multinational, randomized, double-blind, placebo-controlled clinical trial. SETTING: Seventeen ICUs or emergency departments in …

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Awake Venovenous Extracorporeal Membrane Oxygenation in the Intensive Care Unit: Challenges and Emerging Concepts

Fabio Guarracino, Rubia Baldassarri, Giulia Brizzi, Alessandro Isirdi et autres

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Acute normovolemic hemodilution in cardiac surgery: Rationale and design of a multicenter randomized trial

Fabrizio Monaco, Fabio Guarracino, Igor Vendramin, Chong Lei et autres

BACKGROUND: Minimizing the use of blood component can reduce known and unknown blood transfusion risks, preserve blood bank resources, and decrease healthcare costs. Red Blood Cell (RBC) transfusion is common after cardiac surgery and associated with adverse perioperative outcomes, including mortality. Acute …

it, ru, cn, us, tr, jp, br, sg, th, sa, au (code pays fourni par la source)

[Tracheal rupture treated with robotic surgery: the importance of evidence-based practice in nursing management. A case report].

Stefano Migliaccio, Ernesto Cammarano, Giulia Brizzi, Pietro Bertini et autres

. Tracheal rupture treated with robotic surgery: the importance of evidence-based practice in nursing management. A case report. Tracheal rupture is a very rare condition with high morbidity and mortality. While it has a multifactorial etiology, however it occurs most frequently after …

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High dose esomeprazole as an anti-inflammatory agent in sepsis: Protocol for a randomized controlled trial

Giacomo Monti, Aidos K. Konkayev, Sonia Carta, Nikola Bradić et autres

BACKGROUND: Sepsis is caused by dysregulated immune responses due to infection and still presents high mortality rate and limited efficacious therapies, apart from antibiotics. Recent evidence suggests that very high dose proton pump inhibitors might regulate major sepsis mediators' secretion by monocytes, …

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Continuous vs Intermittent Meropenem Administration in Critically Ill Patients With Sepsis

Giacomo Monti, Nikola Bradić, Matteo Marzaroli, Aidos K. Konkayev et autres

Importance: Meropenem is a widely prescribed β-lactam antibiotic. Meropenem exhibits maximum pharmacodynamic efficacy when given by continuous infusion to deliver constant drug levels above the minimal inhibitory concentration. Compared with intermittent administration, continuous administration of meropenem may improve clinical outcomes. Objective: To …

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Early versus late tracheostomy for traumatic brain injury: a systematic review and meta-analysis

Pietro Bertini, Alberto Marabotti, Gianluca Paternoster, Fabio Sangalli et autres

INTRODUCTION: Tracheostomy is the most frequent bedside surgical procedure performed on patients with traumatic brain injury who require mechanical ventilation. To compare the effects of early tracheostomy vs. late tracheostomy on the duration of mechanical ventilation in patients with traumatic brain injury, …

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Beneficial effects of levosimendan to wean patients from VA-ECMO: a systematic review and meta-analysis

Pietro BERTINI, Gianluca Paternoster, Giovanni Landoni, Marco FALCONE et autres

INTRODUCTION: Patients with refractory cardiogenic shock can benefit from veno-arterial extracorporeal membrane oxygenation (VA-ECMO). The use of levosimendan in VA-ECMO patients may facilitate weaning and enhance survival. EVIDENCE ACQUISITION: , 2021. Eligible clinical trials and observational studies reporting the use of levosimendan …

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Ventriculo-arterial coupling in the intensive cardiac care unit: A non-invasive prognostic parameter

Paolo Trambaiolo, Ilaria Figliuzzi, Marta Salvati, Pietro Bertini et autres

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AN UNEXPECTED INTRAOPERATIVE UNUSUAL CASE OF AORTIC STENOSIS

Pietro Bertini, Gianluca Paternoster, Giulia Brizzi, Andrea Colli et autres

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Preventing Severe Acute Respiratory Syndrome Coronavirus-2 Exhalation Upon Tracheal Extubation in the Intensive Care Unit: A Case Series

Fabio Guarracino, Francesco Forfori, Giulia Brizzi, Pietro Bertini

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a highly infectious virus transmitted by inhalation of infected matter containing live virus or by exposure from contaminated surfaces. Aerosol-generating procedures (AGPs) create an increased risk of airborne transmission of infection. Tracheal extubation of coronavirus …

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Strain elastography for the assessment of skin nodules in dogs

Giulia Brizzi, Paola Crepaldi, P. Roccabianca, Simona Morabito et autres

BACKGROUND: Strain elastography (SE) is a modern imaging technology that provides an additional way of evaluating the changes in soft tissue elasticity caused by pathophysiological processes. Despite its widespread use in human medicine, only a few studies on the application of SE …

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