Jon Rask

Design logic visualizations as boundary objects in design

Lauren M. White, Jon Rask, Kathleen Bond, Erik Frankforter et autres

ABSTRACT: Design teams commonly need to explain the rationale or logic behind how they frame design challenges and develop a particular design concept and not others. This paper explores the use of Design Logic Visualizations (DLV) as a boundary object to enhance …

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Applications of UAS Technologies to Create Resilient Rural Communities

Michael J. Logan, Lauren White, Angela Bowes, Erik Frankforter et autres

The NASA Convergent Aeronautics Solutions (CAS) project convened a team of researchers to investigate the needs of rural communities with an eye towards the application of Unmanned Aircraft Systems (UAS) technologies. The Connecting Rural Communities and Capabilities (3C) team gathered data on …

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Inflammasome-Inhibiting Nanoligomers Are Neuroprotective against Space-Induced Pathology in Healthy and Diseased Three-Dimensional Human Motor and Prefrontal Cortex Brain Organoids

Sadhana Sharma, Vincenzo S. Gilberto, Jon Rask, Anushree Chatterjee et autres

The microgravity and space environment has been linked to deficits in neuromuscular and cognitive capabilities, hypothesized to occur due to accelerated aging and neurodegeneration in space. While the specific mechanisms are still being investigated, spaceflight-associated neuropathology is an important health risk to …

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Inflammasome-Inhibiting Nanoligomers are Neuroprotective Against Space-Induced Pathology in Healthy and Diseased 3D Human Motor and Pre-Frontal Cortex Brain Organoids

Sadhana Sharma, Vincenzo S. Gilberto, Jon Rask, Anushree Chatterjee et autres

ABSTRACT Microgravity and space environment has been linked to deficits in neuromuscular and cognitive capabilities, hypothesized to occur due to accelerated aging and neurodegeneration in space. While the specific mechanisms are still being investigated, spaceflight-associated neuropathology is an important health risk to …

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A Mission Simulating the Search for Life on Mars with Automated Drilling, Sample Handling, and Life Detection Instruments Performed in the Hyperarid Core of the Atacama Desert, Chile

C. Stoker, B. Glass, Arwen Davé, L. Kobayashi et autres

We report on a field demonstration of a rover-based drilling mission to search for biomolecular evidence of life in the arid core of the Atacama Desert, Chile. The KREX2 rover carried the Honeybee Robotics 1 m depth The Regolith and Ice Drill …

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Biomonitoring and precision health in deep space supported by artificial intelligence

Ryan T. Scott, Lauren Sanders, Erik Antonsen, Jaden J. A. Hastings et autres

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Biological research and self-driving labs in deep space supported by artificial intelligence

Lauren Sanders, Ryan T. Scott, Jason H. Yang, Amina A. Qutub et autres

Space biology research aims to understand fundamental spaceflight effects on organisms, develop foundational knowledge to support deep space exploration and, ultimately, bioengineer spacecraft and habitats to stabilize the ecosystem of plants, crops, microbes, animals and humans for sustained multi-planetary life. To advance …

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Lunar Dust Toxicity

Jon Rask

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Beyond Low Earth Orbit: Biomonitoring, Artificial Intelligence, and Precision Space Health

Ryan T. Scott, Erik Antonsen, Lauren Sanders, Jaden J. A. Hastings et autres

Human space exploration beyond low Earth orbit will involve missions of significant distance and duration. To effectively mitigate myriad space health hazards, paradigm shifts in data and space health systems are necessary to enable Earth-independence, rather than Earth-reliance. Promising developments in the …

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Beyond Low Earth Orbit: Biological Research, Artificial Intelligence, and Self-Driving Labs

Lauren Sanders, Jason H. Yang, Ryan T. Scott, Amina A. Qutub et autres

Space biology research aims to understand fundamental effects of spaceflight on organisms, develop foundational knowledge to support deep space exploration, and ultimately bioengineer spacecraft and habitats to stabilize the ecosystem of plants, crops, microbes, animals, and humans for sustained multi-planetary life. To …

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Strategy for Integration of Life Sciences in Space

Jon Rask, P. J. Boston, Edward M. Goolish

The disciplines of astrobiology (AB) and space biology (SB) clearly have common interests, however they have not been pursued jointly.SB and AB, together with planetary protection and human spaceflight, are inextricably linked, both intellectually and technologically.They must now be linked operationally.

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Temporal RNA Integrity Analysis of Archived Spaceflight Biological Samples

Ryan T. Scott, Elizabeth Delgadillo Talburt, Alison J. French, Danielle K. Lopez et autres

Spaceflight experiments have utilized model organisms for decades to assess effects of microgravity on biological systems. In many of those experiments, obtaining and assessing tissues from only a few biological systems are of interest to their Principal Investigators. To maximize scientific return …

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