Tuhin Bhowmick

Kuragel—liquid cornea: A bioengineered solution for corneal blindness

Parinita Agrawal, Abha Gour, Mehak Sapra, Anil Tiwari et autres

in (code pays fourni par la source)

Contributors

Carla J. Abbott, Anas Abu-Dieh, Parinita Agrawal, Penelope J. Allen et autres

Corneal Microstructural Alterations in Vernal Keratoconjunctivitis and Keratoconus Assessed by In Vivo Confocal Microscopy

Bharti Sangwan, Jyoti Sangwan, Amulya Thatigotla Naga, Jyoti Rajput et autres

Spinning with exosomes: electrospun nanofibers for efficient targeting of stem cell-derived exosomes in tissue regeneration

Ritu Raj, Parinita Agrawal, Utkarsh Bhutani, Tuhin Bhowmick et autres

Electrospinning technique converts polymeric solutions into nanoscale fibers using an electric field and can be used for various biomedical and clinical applications. Extracellular vesicles (EVs) are cell-derived small lipid vesicles enriched with biological cargo (proteins and nucleic acids) potential therapeutic applications. In …

Kuragel: A biomimetic hydrogel scaffold designed to promote corneal regeneration

Parinita Agrawal, Anil Tiwari, Suvro Kanti Chowdhury, Mehak Vohra et autres

Cornea-related injuries are the most common cause of blindness worldwide. Transplantation remains the primary approach for addressing corneal blindness, though the demand for donor corneas outmatches the supply by millions. Tissue adhesives employed to seal corneal wounds have shown inefficient healing and …

in, us (code pays fourni par la source)

Biopolymeric corneal lenticules by digital light processing based bioprinting: a dynamic substitute for corneal transplant

Utkarsh Bhutani, Namit Dey, Suvro Kanti Chowdhury, Neha Waghmare et autres

Digital light processing (DLP) technology has gained significant attention for its ability to construct intricate structures for various applications in tissue modeling and regeneration. In this study, we aimed to design corneal lenticules using DLP bioprinting technology, utilizing dual network bioinks to …

in (code pays fourni par la source)

Chemical (Alkali) Burn-Induced Neurotrophic Keratitis Model in New Zealand Rabbit Investigated Using Medical Clinical Readouts and In Vivo Confocal Microscopy (IVCM)

Mehak Vohra, Abha Gour, Jyoti Rajput, Bharti Sangwan et autres

PURPOSE: Chemical eye injury is an acute emergency that can result in vision loss. Neurotrophic keratitis (NK) is the most common long-term manifestation of chemical injury. NK due to alkali burn affects ocular surface health and is one of its most common …

in (code pays fourni par la source)

In vitro Assay to Examine the Function of Tears on Corneal Epithelial Cells

Moumita Mondal, Mehak Vohra, Jyoti Sangwan, Sudhir Verma et autres

Tears contain numerous secreted factors, enzymes, and proteins that help in maintaining the homeostatic condition of the eye and also protect it from the external environment. However, alterations to these enzymes and/or proteins during pathologies such as mechanical injury and viral or …

in, us (code pays fourni par la source)

Comparison of Transcription Elongation Rates of Three RNA Polymerases in Real Time

Priyanka Tare, Tuhin Bhowmick, Gurunath Katagi, Arnab China

High Resolution Image Download MS PowerPoint Slide RNA polymerases (RNAPs) across the bacterial kingdom have retained a conserved structure and function. In spite of the remarkable similarity of the enzyme in different bacteria, a wide variation is found in the promoter–polymerase interaction, …

in (code pays fourni par la source)

Bioprinting of exosomes: Prospects and challenges for clinical applications

Shivaram Selvam, Tuhin Bhowmick, Arun Chandru

453Three-dimensional bioprinting (3DBP) is an additive manufacturing technique that has emerged as a promising strategy for the fabrication of scaffolds, which can successfully recapitulate the architectural, biochemical, and physical cues of target tissues. More importantly, 3DBP offers fine spatiotemporal control and high …

Prolonged Inflammation and Infectious Changes in the Corneal Epithelium Are Associated with Persistent Epithelial Defect (PED)

Tanmoy Dutta, Jyoti Sangwan, Moumita Mondal, Mehak Vohra et autres

Purpose: Failure of rapid re-epithelialization within 10–14 days after corneal injury, even with standard supportive treatment, is referred to as persistent corneal epithelial (CE) defect (PED). Though an array of genes regulates reepithelization, their mechanisms are poorly understood. We sought to understand …

in, se (code pays fourni par la source)

Print me a cornea - Are we there yet?

Midhun Ben Thomas, Shivaram Selvam, Parinita Agrawal, Prayag Bellur et autres

in (code pays fourni par la source)