Leandro Andrés Escobar-Herrera

Exploring L-tyrosine and L-DOPA biosynthesis in faba bean ( Vicia faba L.)

Xinxing Xia, Henryk Straube, Denise E. Blume, Davide Mancinotti et autres

Abstract Background and Aims L-DOPA is an important pharmaceutical that accumulates to high levels in the legume faba bean ( Vicia faba ). L-DOPA is likely derived from L-tyrosine but the responsible enzyme (L-tyrosine oxidase) remains unknown. Availability of L-tyrosine may be …

dk, cn, se, at (code pays fourni par la source)

Raw data, R code and analyses related to gene-to-metabolite analysis using Pearson's correlation coefficient from the research article 'Exploring L-tyrosine and L-DOPA biosynthesis in faba bean (Vicia faba L.)'

Hester Sheehan, Fernando Geu-Flores, Davide Mancinotti, Leandro Andrés Escobar-Herrera

Dataset description: These datasets and R code were used to implicate L-tyrosine oxidase candidates in faba bean (Vicia faba) using a gene-to-metabolite correlation analysis that uses the Pearson correlation coefficient (PCC). The results derived from this analysis are described in the manuscript …

at, dk (code pays fourni par la source)

Raw data, R code and analyses related to gene-to-metabolite analysis using Pearson's correlation coefficient from the research article 'Exploring L-tyrosine and L-DOPA biosynthesis in faba bean (Vicia faba L.)'

Hester Sheehan, Fernando Geu-Flores, Davide Mancinotti, Leandro Andrés Escobar-Herrera

Dataset description: These datasets and R code were used to implicate L-tyrosine oxidase candidates in faba bean (Vicia faba) using a gene-to-metabolite correlation analysis that uses the Pearson correlation coefficient (PCC). The results derived from this analysis are described in the manuscript …

at, dk (code pays fourni par la source)

SARS-CoV-2 sequencing artifacts associated with targeted PCR enrichment and read mapping

Kirsten Ellegaard, Vithiagaran Gunalan, Raphael Niklaus Sieber, Sharmin Jamshid Baig et autres

Protocols and pipelines for SARS-CoV-2 genome sequencing were rapidly established when the COVID-19 outbreak was declared a pandemic. The most widely used approach for sequencing SARS-CoV-2 includes targeted enrichment by PCR, followed by shotgun sequencing and reference-based genome assembly. As the continued …

dk, au (code pays fourni par la source)

From colonizer to culprit: genomic and clinical insights into S. epidermidis from post-surgical endophthalmitis

Susanna Sagerfors, Leandro Andrés Escobar-Herrera, Thor Bech Johannesen, Marc Stegger et autres

PURPOSE: To describe the clinical characteristics of exogenous episodes of endophthalmitis from which Staphylococcus epidermidis was isolated by vitreous cultures. We also explored the genomic traits of these S. epidermidis isolates and their relatedness to S. epidermidis originating from carriers and from …

se, dk, ch, au (code pays fourni par la source)

High-resolution epidemiological landscape from ~290,000 SARS-CoV-2 genomes from Denmark

Mark P. Khurana, Jacob Liam Curran-Sebastian, Neil Scheidwasser, Christian Morgenstern et autres

Vast amounts of pathogen genomic, demographic and spatial data are transforming our understanding of SARS-CoV-2 emergence and spread. We examined the drivers of molecular evolution and spread of 291,791 SARS-CoV-2 genomes from Denmark in 2021. With a sequencing rate consistently exceeding 60%, …

dk, gb, au, ch (code pays fourni par la source)

SARS-CoV-2 sequencing artifacts associated with targeted PCR enrichment and read mapping

Kirsten Ellegaard, Vithiagaran Gunalan, Raphael Niklaus Sieber, Sharmin Jamshid Baig et autres

Abstract Protocols and pipelines for SARS-CoV-2 genome sequencing were rapidly established when the COVID-19 outbreak was declared a pandemic. The most widely used approach for sequencing SARS-CoV-2 includes targeted enrichment by PCR, followed by shotgun sequencing and reference-based genome assembly. As the …

dk, gb, au (code pays fourni par la source)

Relative Vaccine Protection, Disease Severity and Symptoms Associated with Infection with SARS-CoV-2 Omicron Subvariant Ba.2.86 and Descendent Jn.1: A Danish Nationwide Register-Based Study

Ida Rask Moustsen‐Helms, Peter Bager, Tine Graakjær Larsen, Frederik Trier Møller et autres

dk, Ouganda (code pays fourni par la source)

Virus isolation and neutralisation of SARS-CoV-2 variants BA.2.86 and EG.5.1

Ria Lassaunière, Charlotta Polacek, Magdalena Utko, Karina Medin Sorensen et autres

dk, us, fr, au (code pays fourni par la source)

Neutralisation of SARS-CoV-2 Omicron subvariants BA.2.86 and EG.5.1 by antibodies induced by earlier infection or vaccination

Ria Lassaunière, Charlotta Polacek, Sharmin Jamshid Baig, Kirsten Ellegaard et autres

Abstract Highly mutated SARS-CoV-2 Omicron subvariant BA.2.86 emerged in July 2023. We investigated the neutralisation of isolated virus by antibodies induced by earlier infection or vaccination. The neutralisation titres for BA.2.86 were comparable to those for XBB.1 and EG.5.1, by antibodies induced …

dk, fr, au (code pays fourni par la source)

VC1 catalyses a key step in the biosynthesis of vicine in faba bean

Emilie Björnsdotter, Marcin Nadzieja, Wei Chang, Leandro Andrés Escobar-Herrera et autres

Faba bean (Vicia faba L.) is a widely adapted and high-yielding legume cultivated for its protein-rich seeds1. However, the seeds accumulate the pyrimidine glucosides vicine and convicine, which can cause haemolytic anaemia (favism) in 400 million genetically predisposed individuals2. Here, we use …

dk, fi, gb, de, ca (code pays fourni par la source)

The faba bean pan-transcriptome

Leandro Andrés Escobar-Herrera, Jonathan Kreplak, Marcin Nadzieja, Morgane Térézol et autres

Prod 2020-13e BAP GEAPSI INRA

dk, fr (code pays fourni par la source)