Bento Vidal de Moura Negrini

Characterization of 843 children with Zika-related microcephaly in the first three years of life: An individual participant data meta-analysis of 12 cohorts in the Zika Brazilian Cohorts consortium

Demócrito de Barros Miranda-Filho, Ricardo Arraes de Alencar Ximenes, U R Montarroyos, Marília Rosa Abtibol‐Bernardino et autres

One of the main gaps in characterizing the congenital Zika syndrome (CZS) up to now is the small number of participants in individual studies. Pooling the data together overcomes the sample size-related limitations of individual studies and provides an opportunity for investigating …

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Normocephalic Children Exposed to Maternal Zika Virus Infection Do Not Have a Higher Risk of Neurodevelopmental Abnormalities around 24 Months of Age than Unexposed Children: A Controlled Study

Juannicelle Tenório Albuquerque Madruga Godoi, Sílvia Fabiana Biason de Moura Negrini, Davi Casale Aragon, Paulo Ricardo Higassiaraguti Rocha et autres

Although very few controlled studies are available, in utero Zika virus (ZIKV)-exposed children are considered at risk for neurodevelopmental abnormalities. We aimed to identify whether there is an excess risk of abnormalities in non-microcephalic children born to mothers with confirmed ZIKV infection …

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Linear epitope mapping in the E and NS1 proteins of dengue and Zika viruses: Prospection of peptides for vaccines and diagnostics

Víctor Hugo Aquino, Marcílio Jorge Fumagalli, Angélica Silva, Bento Vidal de Moura Negrini et autres

The arrival of the Zika virus (ZIKV) in dengue virus (DENV)-endemic areas has posed challenges for both differential diagnosis and vaccine development. Peptides have shown promise in addressing these issues. The aim of this study was to identify the linear epitope profile …

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Cranial US in Infants Exposed to Zika Virus: The NATZIG Cohort

Sara Reis Teixeira, Jorge Elías, Conrado Milani Coutinho, Maria Clara Zanon Zotin et autres

Background Studies addressing neuroimaging findings as primary outcomes of congenital Zika virus infection are variable regarding inclusion criteria and confirmatory laboratory testing. Purpose To investigate cranial US signs of prenatal Zika virus exposure and to describe frequencies of cranial US findings in …

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Persistence of Anti-ZIKV-IgG over Time Is Not a Useful Congenital Infection Marker in Infants Born to ZIKV-Infected Mothers: The NATZIG Cohort

Conrado Milani Coutinho, Juliana Fernandes, Aparecida Yulie Yamamoto, Sílvia Fabiana Biason de Moura Negrini et autres

Confirming ZIKV congenital infection is challenging because viral RNA is infrequently detected. We compared the presence of anti-ZIKV-IgM and the persistence of anti-ZIKV-IgG antibodies over 18 months in two cohorts of infants born to ZIKV-infected mothers: Cohort one: 30 infants with typical …

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Early maternal Zika infection predicts severe neonatal neurological damage: results from the prospective Natural History of Zika Virus Infection in Gestation cohort study

Conrado Milani Coutinho, SFBM Negrini, Daniel Cardoso de Almeida e Araújo, Sara Reis Teixeira et autres

OBJECTIVE: To define the prevalence of adverse outcomes of maternal infection in a large cohort of ZIKV-infected Brazilian women and their infants. DESIGN: Prospective population-based cohort study. SETTING: Ribeirão Preto's region's private and public health facilities. POPULATION: Symptomatic ZIKV-infected mothers and their …

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Early maternal Zika infection predicts severe neonatal neurological damage: results from the prospective Natural History of ZIKA Virus Infection in Gestation (NATZIG) cohort study

Conrado Milani Coutinho, Sílvia Fabiana Biason de Moura Negrini, Daniel Brito de Araújo, Sara Reis Teixeira et autres

Objective: To define the prevalence of adverse outcomes according to the gestational age of maternal infection in a large cohort of ZIKV-infected Brazilian women and their infants. Design: Prospective, population-based cohort study. Setting: Ribeirão Preto’s region private and public health facilities. Population: …

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Human Herpesvirus 8 in Perinatally HIV-infected Children with Interstitial Lung Disease

Marcelo Comerlato Scottá, Alexandre Todorovic Fabro, Paula Renata Lima Machado, Simone G. Ramos et autres

INTRODUCTION: Human herpesvirus 8 (HHV-8) is associated with the pathogenesis of Kaposi Sarcoma and interstitial pneumonitis in adults. This study aims to evaluate association between HHV-8 and interstitial lung disease in HIV-infected children. METHODS: HIV-infected children with interstitial pneumonitis underwent lung biopsies …

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Erratum to “Clinical and microbiological implications of invasive pneumococcal disease in hospitalized patients (1998–2013)”

Marta Inês Cazentini Medeiros, Bento Vidal de Moura Negrini, Jorgete Maria e Silva, Samanta Cristine Grassi Almeida et autres

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Clinical and microbiological implications of invasive pneumococcal disease in hospitalized patients (1998–2013)

Marta Inês Cazentini Medeiros, Bento Vidal de Moura Negrini, Jorgete Maria e Silva, Samanta Cristine Grassi Almeida et autres

INTRODUCTION: Infections caused by Streptococcus pneumoniae (pneumococcus) still represent a challenge for health systems around the world. OBJECTIVE: The objective of this study was to assess microbiological and clinical aspects in hospitalized patients with invasive pneumococcus disease between 1998 and 2013. MATERIALS …

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Circumcision as treatment for Zoon’s balanitis in an HIV-positive teenage patient

Flávio de Oliveira Pileggi, Paulo Luis Batista Nogueira, Maria Fernanda de Melo Coelho, Gustavo da Silveira Orsi et autres

In this report we describe a case of the Zoon's balanitis in a boy with HIV (AIDS B2). The clinical presentation, failure of topical treatment, cure by circumcision, and the histopathology findings are presented.

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Abnormalities in growth and in the IGF system can be associated to permanent chronic inflammatory process in HIV-infected children independently of clinical control

M. M. Riaño Ruiz, Soraya Sader Milani, Rodrigo José Custódio, Bento Vidal de Moura Negrini et autres

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)