Ilias P. Nikas

Response to: "Clarifying the position of Iran in global anatomy education: Historical development, curriculum integration, and professional practice"

Michael Hortsch, Virgínia Cláudia Carneiro Girão‐Carmona, Ana Caroline Rocha de Melo Leite, Ilias P. Nikas et autres

us, br, cy, gb, Ghana, in, cn, hk, au (code pays fourni par la source)

Clinical implications of 10-formyltetrahydrofolate dehydrogenase expression in hormone receptor-positive breast cancer

Amira A. Abdellatef, Sergey A. Krupenko, Han Suk Ryu, Ilias P. Nikas et autres

Objective ALDH1L1, a key enzyme in folate metabolism, has been implicated in various cancers, but the clinical significance of its expression in breast cancer remains unclear. Methods We analyzed three cohorts from Seoul National University Hospital: (i) 41 non-matched patient samples (23 …

us (code pays fourni par la source)

Clinical implications of 10-formyltetrahydrofolate dehydrogenase expression in hormone receptor-positive breast cancer

Da Sol Kim, Amira A. Abdellatef, Ilias P. Nikas, Sergey A. Krupenko

Objective: ALDH1L1, a key enzyme in folate metabolism, has been implicated in various cancers, but the clinical significance of its expression in breast cancer remains unclear. Methods: We analyzed three cohorts from Seoul National University Hospital: (i) 41 non-matched patient samples (23 …

kr, cy (code pays fourni par la source)

Immunophenotyping TCF1-expressing TILs: spatial profiling and prognostic value in operable non-small cell lung cancer

Konstantinos Ntostoglou, Georgios Christodoulopoulos, Katie Stoker, Jean Descarpentrie et autres

Background The spatial distribution and functional heterogeneity of tumor-infiltrating lymphocytes (TILs) significantly impact patient outcomes in non-small cell lung cancer (NSCLC). While T cell factor 1 (TCF1) expressing TILs have emerged as key players in sustaining anti-tumor immunity, their subset characterization, localization, …

gr, gb, se, cy, kw, us, ec (code pays fourni par la source)

A global overview of anatomical science education and its present and future role in biomedical curricula

Michael Hortsch, Virgínia Cláudia Carneiro Girão‐Carmona, Ana Caroline Rocha de Melo Leite, Ilias P. Nikas et autres

The four main anatomical sciences, gross anatomy, histology, neuroanatomy, and embryology, are fundamental subjects for most health professionals and biomedical students. Usually taught as part of preclinical basic science training, the anatomical sciences provide a structural understanding of human or animal bodies …

us, br, cy, gb, Ghana, in, cn, hk, au (code pays fourni par la source)

Therapeutic pancreatic cancer biomarkers and pharmacogenetics

Pavel Souček, Veronika Vymetalkova, Cosmeri Rizzato, Stefania Bunduc et autres

FOLFIRINOX and gemcitabine plus nab-paclitaxel represent the most effective chemotherapy regimens for metastatic pancreatic cancer patients nowadays, but the median overall survival remains less than one year. Pharmacogenomics and the individualization of therapy represent a promising strategy, including identifying patients at increased …

cz, it, ro, cy (code pays fourni par la source)

MSN/STAT3 drives cancer stemness and chemoresistance via IL-6/LPAR1 ligand receptor complex in triple-negative breast cancer

Cheng Hyun Lee, Soo Young Park, Jae Seok Lee, Da Sol Kim et autres

BACKGROUND: Resistance to chemotherapy remains a major clinical challenge in triple-negative breast cancer (TNBC), an intrinsic subtype with limited available therapeutic options. The expression of moesin (MSN) is upregulated in TNBC patients, but little is known about the role of MSN in …

kr, cy, us, pr (code pays fourni par la source)

A Comparative Analysis of Diagnostic Performance and Cytomorphologic Features Between Newly Developed WellPrep® and SurePath™ in Serous Effusion Cytology

Ji Eun Choi, Min‐Sun Jin, Da Sol Kim, Ilias P. Nikas et autres

Abstract Introduction: Whereas liquid-based cytology (LBC) is often the preferred method in gynecological and non-gynecological cytopathology compared to conventional preparation, it does have several limitations. This study aims to evaluate the diagnostic accuracy and specific cytomorphologic characteristics of the newly developed WellPrep …

kr, cy (code pays fourni par la source)

The Prognostic Significance of Ki-67 Expression in Breast Cancers Developing Malignant Effusions

Ilias P. Nikas, So Hyeon Yang, Sojung Lim, Hyebin Lee et autres

INTRODUCTION: The aim of this study was to investigate the prognostic significance of Ki-67 in breast cancer patients developing malignant effusions. METHODS: In this retrospective study, 76 breast cancer patients developing a malignant effusion were enrolled. The Ki-67 immunohistochemistry (IHC) findings from …

cy, kr (code pays fourni par la source)

Abstract LB221: Clinical significance of ALDH1L1 expression in hormone receptor positive breast cancer

Amira A. Abdellatef, Han Suk Ryu, Da Sol Kim, Ilias P. Nikas et autres

Abstract Introduction: Breast cancer is a deadly disease affecting millions of women globally. It is highly heterogeneous, with subtypes such as luminal A, luminal B, HER2-enriched, and TNBC, each exhibiting distinct genetic and clinical characteristics, prognoses, and treatment responses. In breast cancer, …

kr, cy (code pays fourni par la source)

Pancreatic neuroendocrine neoplasms (pNENs): Genetic and environmental biomarkers for risk of occurrence and prognosis

Matteo Tacelli, Manuel Gentiluomo, Paolo Biamonte, Justo Pastor Castano et autres

it, es, hr, ch, cy, sk, us (code pays fourni par la source)

Clinical Significance of Different Histology and High-Risk HPV Types in Neuroendocrine Carcinomas of the Cervix

Seung Jun Lee, Seokhyun Lee, Ilias P. Nikas, Misong Kim et autres

This study aimed to investigate the impact of different histologic and high-risk (HR) human papillomavirus (HPV) types on the clinicopathologic characteristics and survival of patients with neuroendocrine carcinoma of the cervix (NEC). We retrospectively reviewed the medical records of patients with NEC …

kr, cn, cy (code pays fourni par la source)