Umberto Siméoni

How much sweating is enough? Predicting thermoregulatory capacity in patients with ectodermal dysplasia based on a minimal pilocarpine-induced sweat volume

Anja Bachfischer, Carola Berking, S. Hadj‐Rabia, Umberto Siméoni et autres

Background Pathogenic EDA gene variants underlying X-linked hypohidrotic ectodermal dysplasia cause either anhidrosis (null mutations) or hypohidrosis (hypomorphic mutations). Due to their inability to sweat, heat-stressed individuals with EDA null mutations are unable to regulate their body temperature without external cooling and …

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Évaluation des apports nutritionnels lors de la transition ménopausique des femmes en France

Pascale Hébel, Luc Marlier, Yolan Peronnet, Victoria Dupuis et autres

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From phenotype-based to biology-driven screening for preterm birth risk: an expert European perspective

Gian Carlo Di Renzo, Nándor Ács, Jose Luis Bartha, Roland Devlieger et autres

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Commentary: Translating the PRIME Trial into European obstetric care

Gian Carlo Di Renzo, Umberto Siméoni, Dilly O. C. Anumba

PRIME trial did not show any differences in the mean gestational age at birth between the groups and given that singleton preterm births occur in a small minority of cases, overall changes in mean ...

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European Consensus Guidelines on the Management of Respiratory Distress Syndrome: 2025

David G. Sweet, Virgilio P. Carnielli, Gorm Greisen, Mikko Hallman et autres

Every year, new evidence emerges about how best to care for tiny babies with respiratory distress. We report the seventh version of "European Guidelines for the Management of RDS" by a panel of European neonatologists and an expert perinatal obstetrician based on …

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Preserved Function of Endothelial Colony-Forming Cells in Female Rats with Intrauterine Growth Restriction: Protection Against Arterial Hypertension and Arterial Stiffness?

Thea Chevalley, Floriane Bertholet, Marion Dübi, Maria Serena Merli et autres

Individuals born after intrauterine growth restriction (IUGR) are at increased risk of long-term cardiovascular complications, including elevated blood pressure, endothelial dysfunction, and arterial stiffness. Endothelial progenitor cells (EPCs), particularly endothelial colony-forming cells (ECFCs), play a critical role in maintaining vascular homeostasis. Previously, …

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Placenta Myo-Inositol in Women at Risk for Gestational Diabetes Mellitus

Pierluigi Di Vinci, Bénazir Siddeek, Isabella Neri, Umberto Siméoni et autres

Keywords myoinositol - placenta - gestational diabetes mellitus - obesity - birth weight Publication History Article published online: 06 November 2025 © 2025. Thieme. All rights reserved. Thieme Medical Publishers, Inc. 333 Seventh Avenue, 18th Floor, New York, NY 10001, USA

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The hidden impact of intrauterine growth restriction in the pathogenesis of metabolic syndrome: Functional and structural alterations in rat visceral adipose tissue

Hanna Coppola, Sandrine Gremlich, David Viertl, Umberto Siméoni et autres

• Male rats born after intrauterine growth restriction (IUGR) exhibited multiple features of metabolic syndrome (MetS) by 6 months of age. • IUGR males demonstrated structural and functional alterations in visceral adipose tissue (VAT), including adipocyte hypertrophy and hyperplasia, as well as …

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Fishing-Related Plastic Pollution on Bocassette Spit (Northern Adriatic): Distribution Patterns and Stakeholder Perspectives

Corinne Corbau, Alexandre Lazarou, Umberto Siméoni

Plastic pollution in marine environments is a globally recognized concern that poses ecological and economic threats. While 80% of plastic originates from land, 20% comes from sea-based sources like shipping and fishing. Comprehensive assessments of fishing-related plastics are limited but crucial for …

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Maternal exposure to high-fat diet induces long-term mitochondrial alterations in the offspring heart

Mariapia Chindamo, Hassib Chehade, Anthony Sordet, Gaël Humbert-Droz et autres

Heart disease is a leading cause of death worldwide, with its prevalence exacerbated by inadequate nutritional intake. Particularly concerning is the elevated risk induced by imbalanced nutrition during development, which can impact lifelong heart health. Recent research has underscored mitochondrial dysregulation as …

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Sexual Dimorphism in Cardiometabolic Diseases: From Development to Senescence and Therapeutic Approaches

Marion Dübi, Laurent Fumeaux, Maria Serena Merli, Alexandre Sarre et autres

The global incidence and prevalence of cardiometabolic disorders have risen significantly in recent years. Although lifestyle choices in adulthood play a crucial role in the development of these conditions, it is well established that events occurring early in life can have an …

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Counseling the breastfeeding woman: diet and supplements for breastmilk quality and quantity

Umberto Siméoni