Thomas Christen

CE-534535-003 ICE VS. TEE-GUIDED LAAO USING WATCHMAN FLX: COMPARATIVE SAFETY AND EFFECTIVENESS AMONG 95,000 PATIENTS IN THE NCDR LAAO REGISTRY

Enrico Ferro, Robert W. Yeh, James Freeman, Jonathan C. Hsu et autres

Scalable magnetic resonance fingerprinting: Incremental inference of high-dimensional elliptical mixtures from large data volumes

Geoffroy Oudoumanessah, Thomas Coudert, Carole Lartizien, Michel Dojat et autres

Magnetic Resonance Fingerprinting (MRF) is an emerging technology with the potential to revolutionize radiology and medical diagnostics. In comparison to traditional magnetic resonance imaging (MRI), MRF enables the rapid, simultaneous, noninvasive acquisition and reconstruction of multiple tissue parameters, paving the way for …

fr, us (code pays fourni par la source)

Abstract 4365954: Outcomes Following Left Atrial Appendage Closure in Older Adults with Different Levels of Frailty

Emily P. Zeitler, Oluseun Alli, Enrico Ferro, Steven J. Filby et autres

Background: Patients who are older and those that are frail are routinely referred for LAAC but may be at increased risk of adverse events following device implant. It is unclear how age and frailty interact and if measures of frailty can support …

us (code pays fourni par la source)

Estimating blood oxygen saturation through susceptibility source separation: A new standpoint on quantitative BOLD models

Lucie Chalet, Sébastien Rigollet, Vasile Stupar, Aurélien Delphin et autres

MR methods have been proposed to estimate blood oxygen saturation in cerebral tissues by exploiting the magnetic susceptibility difference between oxy and deoxyhemoglobin. These models neglect the contribution of extravascular susceptibility sources leading to inaccurate measurements. Recent approaches combined quantitative BOLD and …

fr, it (code pays fourni par la source)

Robust Subspace Clustering Approach for High-Dimensional MRF: Novel Simultaneous Clustering and Dimensionality Reduction at Scale

Geoffroy Oudoumanessah, Thomas Coudert, Antoine Barrier, Aurélien Delphin et autres

Motivation: Magnetic Resonance Fingerprinting (MRF) has become a promising technique for simultaneously estimating several MR tissue parameter maps. However, as the number of parameters increases, existing models encounter significant challenges related to computational power and storage. Goal(s): To address the challenges associated …

MR-WAVES: MR simulations from 3D realistic microvascular networks in a few seconds

Thomas Coudert, Aurélien Delphin, Maitê Marçal, Antoine Barrier et autres

Motivation: Realistic MR signal simulations incorporating microvascular structures and water-diffusion are crucial to understand fMRI BOLD or DSC experiments and are directly applicable in MRF techniques. Yet, they remain computationally challenging. Goal(s): To propose a novel simulation tool that efficiently accounts for …

Advanced MR vascular Fingerprinting

Maitê Marçal, Thomas Coudert, Aurélien Delphin, Antoine Barrier et autres

Motivation: MRI measurements of microvascular network geometries and functions can help better understand brain functions and pathologies. Goal(s): Improve microvascular network estimates with MR vascular Fingerprinting (MRvF). Approach: We generated 45,000 realistic 3D voxels from mouse brain microscopy datasets using advanced segmentation …

Estimating blood oxygen saturation through susceptibility sources separation: a new standpoint on quantitative BOLD models

Lucie Chalet, Sébastien Rigollet, Vasile Stupar, Aurélien Delphin et autres

Motivation: MR methods have been proposed to estimate blood oxygen saturation (SO2) in cerebral tissues by exploiting the magnetic susceptibility difference between oxy and deoxyhemoglobin. These models neglect the contribution of extravascular susceptibility sources leading to inaccurate measurements. Goal(s): Recent approaches tried …

Comparison of left atrial appendage closure and oral anticoagulation after catheter ablation for atrial fibrillation: concomitant and sequential cohorts of the OPTION randomized controlled trial

Oussama M. Wazni, Devi G. Nair, Vijay Iyer, Germán Calle Pérez et autres

Abstract Introduction/Objectives Guidelines recommend continuation of anticoagulation following atrial fibrillation (AF) ablation in patients at high risk for stroke. Left atrial appendage closure (LAAC) has not been well-studied for routine use post ablation. LAAC can be performed in separate procedures with cardiac …

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Translational validation of a MRI-based CMRO2 mapping method for penumbra definition in acute ischemic stroke

Lucie Chalet, Timothé Boutelier, Thomas Christen, Justine Debatisse et autres

Latest challenges in acute ischemic stroke management involve tissue-based approaches to define a tailored ischemic penumbra to each patients. Oxygen metabolism imaging offers new perspectives to tackle these challenges. A fully automated pipeline was developed providing oxygen metabolism parameters from MRI acquisitions …

MARVEL: MR Fingerprinting with Additional micRoVascular Estimates Using Bidirectional LSTMs

Antoine Barrier, Thomas Coudert, Aurélien Delphin, Benjamin Lemasson et autres

fr (code pays fourni par la source)

Comparison of Quantitative BOLD and Vascular MRF for Mapping Brain Oxygenation

Linh N. N. Le, Gregory Wheeler, Thomas Christen, Greg Zaharchuk et autres

We compared two approaches of quantitative Blood-Oxygenation Level-Dependent (qBOLD) and vascular MR Fingerprinting (vMRF) to map brain oxygenation from Gradient-Echo Sampling of Free Induction Decay and Echo (GESFIDE) scans acquired during normoxic, hyperoxic, and hypoxic gas breathing conditions. In 12 healthy subjects, …