Larisa Babenko

Benefits of eculizumab in AQP4+ neuromyelitis optica spectrum disorder: Subgroup analyses of the randomized controlled phase 3 PREVENT trial

Jacqueline Palace, Dean M. Wingerchuk, Kazuo Fujihara, Achim Berthele et autres

BACKGROUND: Antibodies to the aquaporin-4 (AQP4) water channel in neuromyelitis optica spectrum disorder (NMOSD) are reported to trigger the complement cascade, which is implicated in astrocyte damage and subsequent neuronal injury. The PREVENT study demonstrated that the terminal complement inhibitor eculizumab reduces …

gb, us, jp, de, es, kr, tr, ru, my, tw (code pays fourni par la source)

SAFETY ASPECTS WITHOUT LOSS OF EFFECTIVENESS IN THE SWITCH OF PATIENTS WITH MULTIPLE SCLEROSIS FROM THE ORIGINAL DRUG GLATIRAMER ACETATE COPAXONE-TEVA ON THE BIOSIMILAR TIMEXON

Taras O. Simaniv, Mariya N. Zakharova, N. Yu. Lashch, Sergey V. Kotov et autres

The article presents the results of safety fi ndings during international multicenter randomized double-blind, active and placebo-controlled, comparative phase 3 trial. 158 patients with relapsing-remitting multiple sclerosis were randomly assigned into 3 groups: Timexon (glatiramer acetate, manufactured by JSC «BIOCAD», Russia), copaxone-Teva …

ru, us (code pays fourni par la source)

An impact of glatiramer acetate (timexon) on the signs of neurodegeneration process in the neuronal layer of the retina in patients with relapsing-remitting multiple sclerosis

Denis V Sazonov, Larisa Babenko, Asya Yarmoschuk, E M Didrikh

AIM: To perform a comparative study of the results of optical coherence tomography of the retina in patients with relapsing-remitting multiple sclerosis, treated with glatiramer acetate (timexon). MATERIAL AND METHODS: The study included 19 patients (16 women and 3 men) with relapsing-remitting …

ru (code pays fourni par la source)

Safety and efficacy of eculizumab in anti-acetylcholine receptor antibody-positive refractory generalised myasthenia gravis (REGAIN): a phase 3, randomised, double-blind, placebo-controlled, multicentre study

James F. Howard, Kimiaki Utsugisawa, Michael G Benatar, Hiroyuki Murai et autres

us, jp, es, gb, dk, it (code pays fourni par la source)

CLINICAL CASE OF THYROID TUBERCULOSIS

N. M. Koretskаya, Е. Н. Гринь, Larisa Babenko, Бекузаров Сергей Сосламбекович

The article presents the clinical case of thyroid tuberculosis, diagnosed during thyroidectomy in the female patient suffering from nodular toxic goiter. Doctors are to be made aware about the rare localization of tuberculosis for its timely detection.

A retrospective analysis of the effect of pregnancy on the course of multiple sclerosis

Ekaterina Valerievna Popova, D. S. Korobko, E V Bulatova, Albina A. Melnikova et autres

AIM: For a long time it was believed that pregnancy worsens the clinical course of multiple sclerosis. In several European countries, there have been several studies that have demonstrated remission of autoimmune aggression during pregnancy. We studied the effect of pregnancy on …

ru (code pays fourni par la source)