0972 Hailey-Hailey disease model reveals dual MEK and ROCK inhibition as a therapeutic strategy
J. L. Ayers, A. Tiwaa, A. Parihar, M. Martin et autres
0 citationsJournal of Investigative Dermatology
A. Tiwaa
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11Publications signalées
1Citations signalées
1Affiliations récentes
Institutions déclarées
Domaines associés
Genetic and rare skin diseases.Skin and Cellular Biology ResearchHedgehog Signaling Pathway StudiesAutophagy in Disease and TherapyEndoplasmic Reticulum Stress and Disease
Publications récentes
0576 Keratin 5 is essential for modulating ERK signaling to coordinate keratinocyte morphogenesis during epidermal differentiation
K. Schmidt, A. Tiwaa, A. Parihar, A. Coon et autres
0 citationsJournal of Investigative Dermatology
244 A human epidermal model of keratin 5 loss-of-function reveals potential therapeutic strategies for epidermolysis bullosa simplex
Kerstin Schmidt, A. Tiwaa, Anthony Coon, MK Sarkar et autres
0 citationsJournal of Investigative Dermatology
0548 Hailey-Hailey disease models reveal impaired cadherin expression and localization along with actin dysregulation as key pathogenic drivers that weaken intercellular adhesion
J. L. Ayers, A. Tiwaa, Arpana Parihar, C.J. Tam et autres
0 citationsJournal of Investigative Dermatology
0501 Keratin 5 knockout dysregulates keratinocyte differentiation and epidermal morphogenesis and reveals potential pathogenic drivers of epidermolysis bullosa simplex
Kerstin Schmidt, A. Tiwaa, Anthony Coon, Mrinal K. Sarkar et autres
0 citationsJournal of Investigative Dermatology
553 Dampening ERK hyper-activation rescues cell-cell adhesion in a model of Grover disease
A. Tiwaa, S.A. Zaver, Christopher J. Johnson, Paul W. Harms et autres
0 citationsJournal of Investigative Dermatology
366 Epidermal keratinocytes activate the autophagy receptor TEX264 to trigger endoplasmic reticulum degradation during cornification
C.J. Johnson, Birgit Lorenz, A. Tiwaa, Reeteka Kudallur et autres
0 citationsJournal of Investigative Dermatology
395 Hailey-Hailey disease model identifies actin dysregulation and oxidative stress as pathogenic drivers compromising intercellular adhesion
J. L. Ayers, A. Tiwaa, C.J. Tam, Mrinal K. Sarkar et autres
0 citationsJournal of Investigative Dermatology
LB1722 Ablating ATP2C1 in human keratinocytes impairs intercellular adhesion, disrupts epidermal integrity, and reveals therapeutic targets for Hailey-Hailey disease
J. L. Ayers, A. Tiwaa, Mrinal K. Sarkar, Jóhann E. Guðjónsson et autres
1 citationJournal of Investigative Dermatology
321 A human tissue model of Darier disease reveals MEK as a novel therapeutic target downstream of SERCA2 deficiency
S.A. Zaver, M. Sarkar, A. Tiwaa, Jieni Zou et autres
0 citationsJournal of Investigative Dermatology
699 TEX264 drives autophagic degradation of the endoplasmic reticulum in keratinocytes during epidermal differentiation and upon ER stress
C.L. Simpson, C.J. Johnson, A. Tiwaa
0 citationsJournal of Investigative Dermatology
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