Accès ouvert
2024
article
OpenAlex
Stanislav Glezer, Michael W Hess, Alan K. Kamada
Portable oxygen concentrators (POCs) are medical devices that provide supplemental oxygen to patients requiring long-term oxygen therapy. However, little information is available on day-to-day patterns of how or even whether patients actively switch between their POC mobility features and flow setting options. …
us
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Accès ouvert
2021
letter
OpenAlex
Alan K. Kamada, Xinmei Jiang, Yang Wang, Bal Johal
gas analysis, part 2 Clemens Ager, Karl Unterkofler, Pawel Mochalski et al.
gb
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2016
article
OpenAlex
Ellen Sher, Donald Y.M. Leung, Wendy Surs, J C Kam et autres
The current study examined whether alterations in glucocorticoid receptor (GR) binding contribute to poor response to glucocorticoid therapy in asthma. 29 asthma patients with forced expiratory volume in 1 s (FEV1) 30% after a I-wk course of oral prednisone 20 mg twice …
Accès ouvert
2015
article
OpenAlex
Robert C. Strunk, Ryan Colvin, Erick Forno, Ana María Arbeláez et autres
us, ca
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2008
book-chapter
OpenAlex
Alan K. Kamada, Stanley J. Szefler
This chapter contains section titled: Introduction Chemistry and Structure-Activity Relationships The Glucocorticoid Receptor Molecular Mechanisms of Glucocorticoids Cellular Mechanisms of Glucocorticoids Effects on Cell Trafficking and Chemotaxis Effects on Mediator Synthesis and Release Effects on Vascular Permeability Effects on P-Adrenergic Receptor Activity …
1999
article
OpenAlex
Alan K. Kamada
Racine-Poon A, Botta L, Chang TW, et alClin Pharmacol Ther.621997675690A dose-ranging study was performed to evaluate the safety and efficacy, and pharmacodynamics and pharmacokinetics of CGP 51901, a recombinant monoclonal mouse-human chimeric anti-human immunoglobulin-E (IgE) antibody, in adults with allergic rhinitis. This …
us
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1999
book-chapter
OpenAlex
Alan K. Kamada, Stanley J. Szejler
Glucocorticoids have been used in the treaunent of asthma for many years and are now a cornerstone of asthma therapy. Recent attention has been paid to the mechanisms of glucocorticoids and their effects on the wide array of inflammatory cells thought to …
1997
article
OpenAlex
Alan K. Kamada, Stanley J. Szefler
Although discussed for many years, systemic adverse effects from inhaled corticosteroid therapy remains a complicated and controversial topic. It is by now well-known that inhaled corticosteroids may affect growth, bone, and adrenal function, yet the clinical relevance and the risks for such …
us
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1997
article
OpenAlex
Alan K. Kamada, Matthew B. Wiener, Nicole LaVallee, Maryanne Bartoszek Scott et autres
To compare pharmacokinetics of liquid prednisolone and prednisone solutions and to assess relative bioavailability, six healthy adult men were administered 15 mg of each formulation. Blood samples were obtained and assayed for plasma prednisolone concentrations by high-performance liquid chromatography. Peak concentration was …
us
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1996
article
OpenAlex
Alan K. Kamada
The revised labeling for oral theophylline products recently issued in January 1995 by the United States' Food and Drug Administration is reviewed. Important revisions have been made in the following sections: Clinical Pharmacology, Indications and Usage, Warnings, Precautions, Overdosage, and Dosage and …
us
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1996
article
OpenAlex
Alan K. Kamada
The relative potencies of the inhaled steroids beclomethasone dipropionate, flunisolide, and triamcinolone acetonide are approximately equivalent for both topical and systemic effect when the dosage is expressed in µg. Relative potencies on the basis of actuations are therefore proportional to the number …
us
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1996
article
OpenAlex
Sally E. Wenzel, Alan K. Kamada
OBJECTIVE: To introduce and review zileuton, an orally active 5-lipoxygenase inhibitor that represents the first of a new class of medications to be used in the treatment of asthma. DATA SOURCES: A MEDLINE search (from 1966 to December 1995) was performed to …
us
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