Vivien Low

Isoleucine and valine promote prostate cancer progression via propionyl-CoA-mediated cholesterol metabolism

Zhongchi Li, Shuchen Liu, Wenbing Jin, Leyi Xiao et autres

Enhanced cholesterol synthesis and lipid droplet accumulation are hallmarks of aggressive prostate cancer, yet how tumour cells sense metabolic inputs to dynamically regulate cholesterol homeostasis remains poorly defined. Here we uncover a metabolic signalling mechanism in which prostate cancer cells remodel propionyl-CoA …

us, jp (code pays fourni par la source)

Figure S2 from Stromal KITL/SCF Maintains Pancreas Tissue Homeostasis and Restrains Tumor Progression

Maria Kathrina Oñate, Chet Huan Oon, Sohinee Bhattacharyya, Vivien Low et autres

Supplementary Figure S2: Kitl is expressed by healthy pancreatic mesenchyme and reduced upon activation to a CAF phenotype

Figure S1 from Stromal KITL/SCF Maintains Pancreas Tissue Homeostasis and Restrains Tumor Progression

Maria Kathrina Oñate, Chet Huan Oon, Sohinee Bhattacharyya, Vivien Low et autres

Supplementary Figure S1: scRNA-seq reveals gene expression programs in PSCs and PSC-derived CAFs

Figure S4 from Stromal KITL/SCF Maintains Pancreas Tissue Homeostasis and Restrains Tumor Progression

Maria Kathrina Oñate, Chet Huan Oon, Sohinee Bhattacharyya, Vivien Low et autres

Supplementary Figure S4: Stromal KITL promotes pancreas tissue homeostasis

Figure S3 from Stromal KITL/SCF Maintains Pancreas Tissue Homeostasis and Restrains Tumor Progression

Maria Kathrina Oñate, Chet Huan Oon, Sohinee Bhattacharyya, Vivien Low et autres

Supplementary Figure S3: Stromal KITL promotes regulation of pancreas tissue architecture

Pressure injury severity and trajectory: A 5-year cohort study in an Australian health district

Michelle Barakat‐Johnson, Katja Heuer, Darren Dela Rosa, Natalie Ko et autres

AIM: To investigate outcomes of severe hospital-acquired pressure injuries including Stage 3, Stage 4, Unstageable and Suspected Deep Tissue Injuries and examine wound trajectories, patient characteristics and patterns of wound progression over time. MATERIALS AND METHODS: We performed a retrospective analysis of …

au (code pays fourni par la source)

Data from Stromal KITL/SCF Maintains Pancreas Tissue Homeostasis and Restrains Tumor Progression

Maria Kathrina Oñate, Chet Huan Oon, Sohinee Bhattacharyya, Vivien Low et autres

Abstract Components of normal tissue architecture serve as barriers to tumor progression. Inflammatory and wound-healing programs are requisite features of solid tumorigenesis, wherein alterations to immune and nonimmune stromal elements enable loss of homeostasis during tumor onset. The precise mechanisms by which …

Figure S3 from Stromal KITL/SCF Maintains Pancreas Tissue Homeostasis and Restrains Tumor Progression

Maria Kathrina Oñate, Chet Huan Oon, Sohinee Bhattacharyya, Vivien Low et autres

Supplementary Figure S3: Stromal KITL promotes regulation of pancreas tissue architecture

Figure S2 from Stromal KITL/SCF Maintains Pancreas Tissue Homeostasis and Restrains Tumor Progression

Maria Kathrina Oñate, Chet Huan Oon, Sohinee Bhattacharyya, Vivien Low et autres

Supplementary Figure S2: Kitl is expressed by healthy pancreatic mesenchyme and reduced upon activation to a CAF phenotype

Figure S1 from Stromal KITL/SCF Maintains Pancreas Tissue Homeostasis and Restrains Tumor Progression

Maria Kathrina Oñate, Chet Huan Oon, Sohinee Bhattacharyya, Vivien Low et autres

Supplementary Figure S1: scRNA-seq reveals gene expression programs in PSCs and PSC-derived CAFs

Figure S4 from Stromal KITL/SCF Maintains Pancreas Tissue Homeostasis and Restrains Tumor Progression

Maria Kathrina Oñate, Chet Huan Oon, Sohinee Bhattacharyya, Vivien Low et autres

Supplementary Figure S4: Stromal KITL promotes pancreas tissue homeostasis

Stromal KITL/SCF Maintains Pancreas Tissue Homeostasis and Restrains Tumor Progression

Maria Kathrina Oñate, Chet Huan Oon, Sohinee Bhattacharyya, Vivien Low et autres

ABSTRACT: Components of normal tissue architecture serve as barriers to tumor progression. Inflammatory and wound-healing programs are requisite features of solid tumorigenesis, wherein alterations to immune and nonimmune stromal elements enable loss of homeostasis during tumor onset. The precise mechanisms by which …

us (code pays fourni par la source)