Trygve Hausken

Low Small Intestinal PYY Immunoreactive Cell Density and PYY Gene Expression in Patients With Familial GUCY2C Diarrhea Syndrome

Tarek Mazzawi, Trygve Hausken

ABSTRACT Familial GUCY2C diarrhea syndrome (FGDS) is an autosomal dominant disorder found in 32 members of a Norwegian family and caused by a heterozygous missense resulting in chronic diarrhea. The study aimed to investigate any abnormality in the enteroendocrine cells in the …

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Increase in circulating GLP-1 following low FODMAP diet in irritable bowel syndrome patients

Ingeborg Brønstad, Eline Margrete Randulff Hillestad, Elisabeth Kjelsvik Steinsvik, Trygve Hausken et autres

Background: Fermentable oligosaccharides, disaccharides, monosaccharides and polyols (FODMAP) as well as glucagon-like peptide-1 (GLP-1) have independently been implicated in irritable bowel syndrome (IBS) pathophysiology. However, there is a lack of studies that assess how low FODMAP diet affects circulating GLP-1 levels in …

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Brain Morphometry and Cognitive Features in the Prediction of Irritable Bowel Syndrome

Arvid Lundervold, Ben René Bjørsvik, Julie Billing, Birgitte Berentsen et autres

Background/Objectives: Irritable bowel syndrome (IBS) is a gut–brain disorder characterized by abdominal pain, altered bowel habits, and psychological distress. While brain–gut interactions are recognized in IBS pathophysiology, the relationship between brain morphometry, cognitive function, and clinical features remains poorly understood. The study …

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Brain Morphometry and Cognitive Features in Prediction of Irritable Bowel Syndrome

Arvid Lundervold, Ben René Bjørsvik, Julie Billing, Birgitte Berentsen et autres

Background/Objectives: Irritable bowel syndrome (IBS) is a gut-brain disorder characterized by abdominal pain, altered bowel habits, and psychological distress. While brain-gut interactions are recognized in IBS pathophysiology, the relationship between brain morphometry, cognitive function, and clinical features remains poorly understood. The study …

Correction: The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults

Ingrid Revheim, Simon Ballance, Adelheid Fretland Standal, Anne Rieder et autres

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The Effects of Digital eHealth Versus Onsite 2-Day Group-Based Education in 255 Patients With Irritable Bowel Syndrome: Cohort Study

Birgitte Berentsen, Camilla Thuen, Eline Margrete Randulff Hillestad, Elisabeth Kjelsvik Steinsvik et autres

Background: Irritable bowel syndrome (IBS) has a high worldwide prevalence and there are few effective treatment options. Patient education can influence patient behavior that subsequently may lead to changes in attitudes and skills necessary for maintenance or improvement in management of symptom …

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Decoding IBS: a machine learning approach to psychological distress and gut-brain interaction

Astri J. Lundervold, Julie Billing, Birgitte Berentsen, Gülen Arslan Lied et autres

Abstract Purpose Irritable bowel syndrome (IBS) is a diagnosis defined by gastrointestinal (GI) symptoms like abdominal pain and changes associated with defecation. The condition is classified as a disorder of the gut-brain interaction (DGBI), and patients with IBS commonly experience psychological distress. …

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Gastrointestinal effects of GLP-1 receptor agonists: mechanisms, management, and future directions

Ryan J. Jalleh, Christopher K. Rayner, Trygve Hausken, Karen L. Jones et autres

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Fecal bacteria and short‐chain fatty acids in irritable bowel syndrome: Relations to subtype

Erica Sande Teige, Eline Margrete Randulff Hillestad, Elisabeth Kjelsvik Steinsvik, Ingeborg Brønstad et autres

BACKGROUND: The relationship between gut microbiota and irritable bowel syndrome (IBS) subtype is unclear. We aimed to explore whether differences in fecal bacteria composition and short-chain fatty acid (SCFA) levels were associated with subtypes and symptoms of IBS. METHODS: All participants delivered …

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The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial

Ingrid Revheim, Simon Ballance, Adelheid Fretland Standal, Anne Rieder et autres

The cereal fibre β-glucan reduces postprandial glycemia, however, the underlying mechanisms are not fully understood. Thus, the aim of this study was to investigate the acute effect of a β-glucan-enriched oat bread on gastric emptying half-time (T1/2), gastric emptying lag phase (Tlag), …

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Nutritional safety and status following a 12‐week strict low FODMAP diet in patients with irritable bowel syndrome

Eline Margrete Randulff Hillestad, Elisabeth Kjelsvik Steinsvik, Erica Sande Teige, Stella Hellgren Rasmussen et autres

BACKGROUND: A low FODMAP diet (LFD) is an established dietary treatment for patients with irritable bowel syndrome (IBS). However, knowledge on the extended effects of the restriction phase regarding nutrient intake, symptom severity, and quality of life (QoL) is sparse. Therefore, our …

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The acute effect of a β-glucan-enriched oat bread on gastric emptying, GLP-1 response, and postprandial glycaemia and insulinemia: a randomised crossover trial in healthy adults

Ingrid Revheim, Simon Ballance, Adelheid Fretland Standal, Anne Rieder et autres

Abstract Background The cereal fibre β-glucan reduces postprandial glycaemia, however, the underlying mechanisms are not fully understood. Thus, the aim of this study was to investigate the acute effect of a β-glucan-enriched oat bread on gastric emptying half-time (T1/2), gastric emptying lag …

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