André M. Oliveira

Supp Fig S1 from Ubiquitin-Specific Protease 6 mRNA Lipid Nanoparticles Ignite Antitumor Immunity and Suppress Tumorigenesis in Ewing Sarcoma

Ian C. Henrich, Margaret M. Billingsley, Shreya Mondal, Laura Quick et autres

Cytotoxix Effects of USP6 mRNA via IFN-TRAIL

Data from Ubiquitin-Specific Protease 6 mRNA Lipid Nanoparticles Ignite Antitumor Immunity and Suppress Tumorigenesis in Ewing Sarcoma

Ian C. Henrich, Margaret M. Billingsley, Shreya Mondal, Laura Quick et autres

Abstract Ewing sarcoma is an aggressive pediatric cancer that has remained refractory to current therapeutics. Immunotherapy has been unsuccessful in Ewing sarcoma, largely due to poor understanding of how its immune tumor microenvironment is regulated. We recently demonstrated that ubiquitin-specific protease 6 …

Supp Fig S2 from Ubiquitin-Specific Protease 6 mRNA Lipid Nanoparticles Ignite Antitumor Immunity and Suppress Tumorigenesis in Ewing Sarcoma

Ian C. Henrich, Margaret M. Billingsley, Shreya Mondal, Laura Quick et autres

Summary of immunostimulatory effects of USP6

Supp Fig S10 from Ubiquitin-Specific Protease 6 mRNA Lipid Nanoparticles Ignite Antitumor Immunity and Suppress Tumorigenesis in Ewing Sarcoma

Ian C. Henrich, Margaret M. Billingsley, Shreya Mondal, Laura Quick et autres

Summary of anti-tumorigenic mechanism of USP6 mRNA LNPs

Supp Fig S3 from Ubiquitin-Specific Protease 6 mRNA Lipid Nanoparticles Ignite Antitumor Immunity and Suppress Tumorigenesis in Ewing Sarcoma

Ian C. Henrich, Margaret M. Billingsley, Shreya Mondal, Laura Quick et autres

IVT USP6 mRNA recapitulates immunostimulatory effects

Supp Fig S4 from Ubiquitin-Specific Protease 6 mRNA Lipid Nanoparticles Ignite Antitumor Immunity and Suppress Tumorigenesis in Ewing Sarcoma

Ian C. Henrich, Margaret M. Billingsley, Shreya Mondal, Laura Quick et autres

Immune markers in co-cultured PBMCs

Supp Fig S9 from Ubiquitin-Specific Protease 6 mRNA Lipid Nanoparticles Ignite Antitumor Immunity and Suppress Tumorigenesis in Ewing Sarcoma

Ian C. Henrich, Margaret M. Billingsley, Shreya Mondal, Laura Quick et autres

USP6 mRNA triggers immunostimulatory effects in diverse cancer types

Supp Fig S6 from Ubiquitin-Specific Protease 6 mRNA Lipid Nanoparticles Ignite Antitumor Immunity and Suppress Tumorigenesis in Ewing Sarcoma

Ian C. Henrich, Margaret M. Billingsley, Shreya Mondal, Laura Quick et autres

Kaplan Meier of Additional Cancers

Supp Fig S7 from Ubiquitin-Specific Protease 6 mRNA Lipid Nanoparticles Ignite Antitumor Immunity and Suppress Tumorigenesis in Ewing Sarcoma

Ian C. Henrich, Margaret M. Billingsley, Shreya Mondal, Laura Quick et autres

USP6 mRNA effects in AML xenografts

Supp Fig S8 from Ubiquitin-Specific Protease 6 mRNA Lipid Nanoparticles Ignite Antitumor Immunity and Suppress Tumorigenesis in Ewing Sarcoma

Ian C. Henrich, Margaret M. Billingsley, Shreya Mondal, Laura Quick et autres

USP6 mRNA triggers immunostimulatory effects in head and neck cancer

Supp Fig S5 from Ubiquitin-Specific Protease 6 mRNA Lipid Nanoparticles Ignite Antitumor Immunity and Suppress Tumorigenesis in Ewing Sarcoma

Ian C. Henrich, Margaret M. Billingsley, Shreya Mondal, Laura Quick et autres

LNP synthesis

PRRX1-rearranged Fibroblastic Tumors

Carina Dehner, Jorge Torres‐Mora, Judith Jebastin Thangaiah, André M. Oliveira et autres

With the first series of PRRX1 -rearranged tumors published in 2019, the spectrum of these so-called fibroblastic tumors has been expanded. Since then, several smaller case series have been published; however, our understanding of them continues to be quite limited given their …

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