Yanqin Zhang

New therapeutic hope for rare podocytopathies

Yanqin Zhang, Fang Wang, Jie Ding

Podocytopathies are kidney diseases caused by podocyte injury or dysfunction that drives proteinuria or nephrotic syndrome. A significant expansion in understanding of the complex causes and mechanisms of podocyte injury, as well as potential therapeutic approaches, has been achieved over the past …

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Effect of Pregnancy on Kidney Disease Progression in Col4a3-/- Alport Mice

Xinxin Kong, Fang Wang, Xuhui Zhong, Jie Ding et autres

Background: Alport syndrome is an inherited disease, characterized by hematuria, proteinuria, progressive kidney failure and sometimes accompanied with hearing loss and ocular lesions. The effect of pregnancy on the kidney disease progression in females with Alport syndrome remains controversial. Methods: Col4a3-/- female …

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Association between arousal index during REM sleep and the incidence of atrial fibrillation in patients with obstructive sleep apnea

Li‐Da Chen, Yanqin Zhang, Shihua Wu, Chunhua Li et autres

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Noninvasive Optogenetics Realized by iPSC‐Derived Tentacled Carrier in Alzheimer's Disease Treatment

Yuewen Zhai, Fan Gao, Shihao Shi, Qifeng Zhong et autres

Neural-activated optogenetics technique contributing to the "restart" of degenerative neurons offers hope for the treatment of several neurodegenerative diseases. However, the limitations of persistent invasiveness and inadequate repair of the pathological environment strongly hinder its further application. Here, a concept of differentiating …

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A retrospective study of kidney disease in Alport syndrome during and after pregnancy

Xinxin Kong, Jan Boeckhaus, Fang Wang, Chun­yan Shi et autres

Abstract Background During pregnancy, hyperfiltration and other factors are hypothesized to contribute to the progression of kidney disease in women with Alport syndrome. To evaluate the status of kidney disease, clinical data from mothers with Alport syndrome in China and Europe over …

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A Prediction Model of Disease Progression in X-Linked Alport syndrome Based on Clinical Characteristics and Genetic Variants

Mengyao Zeng, Hongling Di, Jie Ding, Yanqin Zhang et autres

Introduction: Alport syndrome (AS) is an inherited kidney disease with significant clinical heterogeneity. Prognosis prediction and risk assessment are important to assist patient care. However, a predictive tool of disease progression is still lacking. Methods: The prediction model was developed in 363 …

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Author Correction: A targetable OSGIN1–AMPK–SLC2A3 axis controls the vulnerability of ovarian cancer to ferroptosis

Mengqi Deng, Fan Tang, Xiangyu Chang, Yanqin Zhang et autres

In the original version of this article, Figs. 7 and 8 are missing scale bars. The original article has been corrected to include the appropriate scale bars in Figs. 7 and 8.

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Evaluating Continuous Veno-venous Hemodiafiltration Treatment Effects on Biomarkers and Outcomes in Sepsis-Induced Acute Kidney Injury

Yingying Gao, Jie Wen, Feng Zhao, Yanqin Zhang

INTRODUCTION: Acute kidney injury (AKI) is commonly precipitated by sepsis. Continuous veno-venous hemofiltration (CVVHD) is a critical intervention for managing AKI, but further exploration is needed to understand its effects on novel renal injury markers and patient outcomes. The aim of this …

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Evaluating Continuous Veno-venous Hemodiafiltration Treatment Effects on Biomarkers and Outcomes in Sepsis-Induced Acute Kidney Injury

Yingying Gao, Jie Wen, Feng Zhao, Yanqin Zhang

Introduction. Acute kidney injury (AKI) is commonly precipitated by sepsis. Continuous veno-venous hemofiltration (CVVHD) is a critical intervention for managing AKI, but further exploration is needed to understand its effects on novel renal injury markers and patient outcomes. The aim of this …

A targetable OSGIN1 − AMPK − SLC2A3 axis controls the vulnerability of ovarian cancer to ferroptosis

Mengqi Deng, Fan Tang, Xiangyu Chang, Yanqin Zhang et autres

Despite advances in various chemotherapy regimens, current therapeutic options are limited for ovarian cancer patients. Oxidative stress-induced growth inhibitor 1 (OSGIN1), which is a tumor suppressor gene known to regulate the cellular stress response and apoptosis, is associated with ovarian cancer development. …

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Prediction of the Soh and Cycle Life of Fast-Charging Lithium-Ion Batteries Based on the Sliding Window Method

Yanqin Zhang, Zehao Yang

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Structural optimization design of pool light shell based on CAE technology

Zhaohu Deng, Yanqin Zhang, Jian Huang

Polycarbonate materials display excellent transparency, comparable to glass, while also boasting impressive mechanical properties, including high flexural strength and stiffness. Consequently, polycarbonate serves as a vital substitute for metals and glass, with wide-ranging applications across various fields. However, polycarbonate materials also face …

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