E. Tao

WCN26-6721 FACTORS ASSOCIATED WITH THE OUTCOMES OF ANCA-ASSOCIATED GLOMERULONEPHRITIS: A MULTICENTER RETROSPECTIVE COHORT STUDY

Nikolay M. Bulanov, Anastasiia S Zykova, Ekaterina Stoliarevich, Dmitrii Dmitrievich Starikov et autres

ru, us (code pays fourni par la source)

Factors associated with the outcomes of ANCA-associated glomerulonephritis: a retrospective cohort study

Nikolay M. Bulanov, E. Tao, E. S. Stolyarevich, Mayra Bulanova et autres

Background. Kidney involvement is one of the prognostically significant manifestations of ANCA-associated vasculitis (AAV). The aim of the study was to evaluate factors associated with kidney survival in patients with biopsy proven ANCA-associated glomerulonephritis (ANCA-GN). Materials and methods. Patients with AAV and …

ru (code pays fourni par la source)

Clinical phenotypes of Fabry disease in adult males and females

Alexey Moiseev, E. Tao, Nikolay M. Bulanov, Эльвира Николаевна Федулова et autres

To study clinical phenotypes of Fabry disease (FD) in adult males and females.

ru (code pays fourni par la source)

WCN25-266 Performance of the different prediction tools for ANCA-associated glomerulonephritis: a retrospective cohort study

Nikolay M. Bulanov, Mayra Bulanova, E. Tao, Mariia A. Litvinova et autres

In the last decades several prediction tools have been proposed to predict outcomes of ANCA-associated glomerulonephritis (ANCA-GN). The recently presented updated ANCA Kidney Risk Score (AKRiS) demonstrated capability to optimize prognostication. The aim of our study was to compare the diagnostic performance …

ru, us (code pays fourni par la source)

Pegunigalsidase alfa: a novel, pegylated recombinant alpha-galactosidase enzyme replacement therapy for Fabry disease

Sergey Valentinovich Moiseev, E. Tao, Alexey Moiseev, Nikolay M. Bulanov

Fabry disease (FD) is a rare hereditary lysosomal storage disease. Enzyme replacement therapy improves symptoms and prevents progression of target organs involvement in patients with FD. Pegunigalsidase alfa is a novel, pegylated recombinant alpha-galactosidase enzyme characterized by prolonged half-life and reduced immunogenicity. …

Basic aspects of meta-analysis. Part 2

E. Tao, M. Yu. Nadinskaia, А. Yu. Suvorov, Nikolay M. Bulanov et autres

Meta-analysis combines the results of several scientific studies to obtain a summary quantitative estimation of effect size in order to compare the results of several studies and to identify patterns among them and possible sources of biases. Since the research teams, patients, …

ru (code pays fourni par la source)

Clinical features of nephropathic cystinosis in adult patients

N. Chebotareva, Alexey N. Tsygin, E. Tao, Valentina V. Maltseva et autres

To evaluate clinical signs and symptoms of nephropathic cystinosis in adult patients.

Chronic renal failure in Fabry disease: the long-term survival on renal replacement therapy

E. Tao, Alexey Moiseev, Nikolay M. Bulanov, Victoria I. Sholomova et autres

To evaluate survival among patients with Fabry disease (FD) depending on the type of renal replacement therapy and to investigate the efficacy of dialysis screening in the early diagnosis of FD in relatives of probands.

The value of registries in the study of rare diseases: Fabry Outcome Survey

E. Tao, Alexey Moiseev, Nikolay M. Bulanov, Sergey Valentinovich Moiseev

Randomized controlled clinical trials are frequently hardly feasible in patients with orphan disorders given the limited number of potential participants and variablity of clinical manifestations and the course of disease. Registry data, particularly for rare diseases, provide additional information regarding long-term treatment …

Fabry disease in female patients: clinical features, outcomes and indications for enzyme replacement therapy

Sergey Valentinovich Moiseev, Nikolay M. Bulanov, Alexey Moiseev, E. Tao et autres

To evaluate clinical features and indications for enzyme replacement therapy (ERT) in female patients with Fabry disease (FD) in the Russian population.

The Benefits of Family Screening in Rare Diseases: Genetic Testing Reveals 165 New Cases of Fabry Disease among At-Risk Family Members of 83 Index Patients

Sergey Valentinovich Moiseev, E. Tao, Alexey Moiseev, Nikolay M. Bulanov et autres

BACKGROUND: Fabry disease (FD, OMIM #301500) is a rare, progressive, X-linked, inherited genetic disease caused by a functional deficiency of lysosomal α-galactosidase, leading to the accumulation of glycosphingolipids in virtually all of the body's cell types and fluids. Patients with rare genetic …

ru, cz, fr, kh (code pays fourni par la source)

Statistical hypothesis testing: general approach in medical research

А. Yu. Suvorov, Nikolay M. Bulanov, A. N. Shvedova, E. Tao et autres

Statistical hypothesis testing is one of the key steps in modern medical research. Initially, scientists formulate a research hypothesis based on which the statistical hypothesis is then developed and statistically tested. This review provides the null and alternative hypotheses’ compiling examples for …

ru (code pays fourni par la source)