Tae‐Young Jung

Greetings From the New Editor-in-Chief

Tae‐Young Jung

Dear colleagues, It is my

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P11.16.A HER2 HETEROGENEITY BETWEEN PRIMARY CANCERS AND BRAIN METASTASES: A RETROSPECTIVE ANALYSIS OF 185 MATCHED PAIRS ACROSS MULTIPLE CANCER TYPES

Joon Lee, JaeHyung Koo, Nick H. Kim, Soo Hyun Kim et autres

Abstract BACKGROUND HER2 overexpression drives tumor aggressiveness and poor prognosis, serving as a crucial therapeutic target in various malignancies. While HER2’s role in breast cancer metastasis and prognosis is well-documented, its heterogeneity in brain metastases (BM) across different primary tumors remains understudied. …

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Central nervous system tumors with BCOR internal tandem duplications: a systematic review of clinical, radiological, and pathological features in 69 cases

Ji Young Lee, Sung Sun Kim, Hee Jo Baek, Tae‐Young Jung et autres

Central nervous system tumors with BCL6 corepressor (BCOR) internal tandem duplications (ITDs) constitute a rare, recently characterized pediatric neoplasm with distinct molecular and histopathological features. To date, 69 cases have been documented in the literature, including our institutional case. These neoplasms predominantly …

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Natural history and predictors of growth in conservatively managed non-functioning pituitary macroadenomas: A volumetric study of 232 tumors

Yeong Jin Kim, Kyung‐Sub Moon, Sue Jee Park, Tae‐Young Jung et autres

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The Impact of Self-efficacy of University Hospital Workers on Innovation Orientation and Goal Commitment: Mediating Effect of Creativity and Moderating Effect of Design Thinking Education

Tae‐Young Jung

인공지능을 비롯한 다양한 기술의 발전으로 의료산업의 환경은 급속도로 발전하고 있으며 기존의 전통적인 진료영역을 벗어나 의료기기, 신약개발 등을 위한 연구 영역의 플랫폼으로 거듭나고 있다. 의료산업 종사자들은 진료에 국한된 근무 환경에서 탈피해 새로운 환경변화에 적응할 필요성이 있는데, 이는 기존 사고의 패러다임을 벗어나 새로운 환경 …

Lifestyle changes and psychological anxiety during the Coronavirus Disease 2019 pandemic: Using the Korean Community Health Survey

Tae‐Young Jung

This study investigated changes in lifestyles and psychological anxiety among Koreans during the Coronavirus Disease 2019 (COVID-19) pandemic using the 2020 data from the nationwide Korean Community Health Survey. The study outcomes were psychological anxiety about the infection and death, due to …

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Metastasis‐enhancing protein KITENIN confers temozolomide resistance on glioblastoma with unmethylated MGMT via upregulation of cancer stem cell makers

Eun‐Jung Ahn, Yeong-Jin Kim, Md Rashedunnabi Akanda, Tae‐Young Jung et autres

Metastasis-enhancing protein KITENIN confers temozolomide resistance on glioblastoma with unmethylated MGMT via upregulation of

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Catalytic Cracking of Crude Waste Plastic Pyrolysis Oil for Enhanced Light Olefin Production in a Pilot-Scale Circulating Fluidized Bed Reactor

Xuan Tin Tran, Eun Sang Kim, Dae Hun Mun, Tae‐Young Jung et autres

Energy-efficient processes using sustainable resources, such as plastic waste, are essential for alleviating environmental pollution and carbon emissions. Herein, we demonstrated the highly efficient direct conversion of crude waste plastic pyrolysis oil (WPPO) into light olefins using a pilot-scale circulating fluidized bed …

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Comprehensive multiomics analysis reveals distinct differences between pediatric choroid plexus papilloma and carcinoma

Yeonsong Choi, Seung Ah Choi, Eun Jung Koh, Ilsun Yun et autres

Choroid plexus tumors (CPTs) are intraventricular tumors derived from the choroid plexus epithelium and occur frequently in children. The aim of this study was to investigate the genomic and epigenomic characteristics of CPT and identify the differences between choroid plexus papilloma (CPP) …

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Meningioma originating from the superior petrosal vein without dural attachment: A case report

Yeong Jin Kim, Shin Jung, Tae‐Young Jung, Kyung-Sub Moon et autres

BACKGROUND: Meningioma in the cerebellopontine angle (CPA) without dural attachment is extremely rare. We report a unique case of meningioma derived from the superior petrosal vein without dural attachment. CASE SUMMARY: A 44-year-old right-handed woman presented with a two-month history of headache …

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Magnet-Guided Temozolomide and Ferucarbotran Loaded Nanoparticles to Enhance Therapeutic Efficacy in Glioma Model

Reju George Thomas, Subin Kim, Thi-Anh-Thuy Tran, Young Hee Kim et autres

Background. The aim of the study was to synthesize liposomal nanoparticles loaded with temozolomide and ferucarbotran (LTF) and to evaluate the theranostic effect of LTF in the glioma model. Methods. We synthesized an LTF that could pass through the Blood Brain Barrier …

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Abstract 1383: Investigation of biological role and cytokine axis of cancer-associated fibroblast (CAF) in lung cancer brain metastasis

Nah Ihm Kim, SM Abdus Salam, Eshrat Jahan, Eun-Jeong Ahn et autres

Abstract Background: Brain metastases (BM) are among the most lethal forms of cancer globally. Lung cancer BM are frequently encountered and are associated with poor prognosis, decreased survival rates, and therapeutic resistances. Cancer-associated fibroblasts (CAFs) have emerged as important players of the …

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