Chun-Wan Yen

Multiplex screening of transferrin receptor-targeted lipid nanoparticles for systemic brain delivery using DNA barcodes

Soumitra Ghosh, Yuchen Fan, Benjamin I. Laufer, William Stephenson et autres

Lipid nanoparticle (LNP) encapsulation has shown strong potential for delivering nucleic acid-based medicines (NABMs); however, effective delivery to the central nervous system (CNS) remains challenging. Here, we combined high-throughput screening (HTS) with a targeting antibody fragment (Fab) against the transferrin receptor—a clinically …

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Aminophosphonate-Derived lipid nanoparticles enable circular RNA delivery for functional recovery after spinal cord injury

Haoyuan Li, Yuebao Zhang, Yichen Zhong, Kaiyuan Guo et autres

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Chemical Fluid Deposition of Ru/MCM-41 as Catalyst for Hydrogenation in Green Environments

Honghong Lin, Chung‐Sung Tan, Chun-Wan Yen

CO Oxidation Catalyzed by Au−Ag Bimetallic Nanoparticles Supported in Mesoporous Silica

Chun-Wan Yen, Meng-Liang Lin, Aiqin Wang, Shin‐An Chen et autres

We report a novel Au−Ag bimetallic nanocatalyst supported on an acidic mesoporous aluminosilicate Au−Ag@APTS-MCM prepared by a two-step synthesis procedure, which is very active for low-temperature CO oxidation. Its catalytic activity is still quite appreciable after 1 year of storage under room …

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Enhancing Stability and Oxidation Activity of Cytochrome c by Immobilization in the Nanochannels of Mesoporous Aluminosilicates

Chia‐Hung Lee, Jun Lang, Chun-Wan Yen, Pei-Chun Shih et autres

Hydrothermally stable and structrurally ordered mesoporous and microporous aluminosilicates with different pore sizes have been synthesized to immobilize cytochrome c (cyt c): MAS-9 (pore size 90 A), MCM-48-S (27 A), MCM-41-S (25 A), and Y zeolites (7.4 A). The amount of cyt …

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