Chris Bower

Impact of hand hygiene on the detection of multidrug-resistant organisms and other pathogens of epidemiologic significance after implementation of an automated hand hygiene monitoring system

Radhika Prakash-Asrani, Kayoko Shioda, Chris Bower, James P. Steinberg et autres

OBJECTIVE: To assess the association between hand hygiene adherence, as measured by an automated hand hygiene monitoring system (AHHMS), and multidrug-resistant organisms and other pathogens of epidemiologic significance (MDRO+). DESIGN: Retrospective cohort study. SETTING: Acute care hospitals within an academic healthcare system. …

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Prospective validation and implementation of a model to identify patients with carbapenem-resistant Enterobacterales (CRE) carriage on admission to acute care hospitals

Hyun Bin Kim, Radhika Prakash-Asrani, Chris Bower, Chad Robichaux et autres

OBJECTIVE: Use the electronic health record (EHR) to prospectively validate a risk prediction tool identifying patients at high-risk for carbapenem-resistant Enterobacterales (CRE). DESIGN: Prospective, cross-sectional analysis. PARTICIPANTS: Adults admitted to two hospitals in Atlanta, Georgia. METHODS: An EHR report calculated a CRE …

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Microbiota Transplantation Among Patients Receiving Long-Term Care

Michael H. Woodworth, Ahmed Babiker, Radhika Prakash-Asrani, C. Christina Mehta et autres

Importance: Intestinal multidrug-resistant organism (MDRO) colonization is highly prevalent in long-term acute care hospital (LTACH) patients and is associated with MDRO infection and transmission. However, there are no therapies approved by the US Food and Drug Administration to reduce intestinal MDRO colonization. …

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Multicenter evaluation of blood culture contamination and blood cultures practices in US acute care hospitals: time for standardization

Valeria Fabre, Yea‐Jen Hsu, Karen C. Carroll, Aaron M. Milstone et autres

Clinical and Laboratory Standards Institute (CLSI) recommends a blood culture contamination (BCC) threshold of <3%, with ≤1% considered optimal. However, there is not a standardized definition of BCC, and the effect of multiple definitions on BCC rates or what definitions laboratories use …

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O02 Skin cancer service disparities across England: what data can tell us about skin cancer diagnosis, referral pathways and treatment received in different NHS trusts

Birgitta van Bodegraven, Sally Vernon, Shehnaz Ahmed, Tania Von Hospenthal et autres

Abstract Skin cancer is the most diagnosed cancer in the UK, with increasing incidence and healthcare demands. The 2021 National Dermatology Getting It Right First Time (GIRFT) report highlighted disparities in skin cancer services across England. However, the underlying data did not …

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Identifying patients at high risk for carbapenem-resistant Enterobacterales (CRE) carriage on admission to acute care hospitals: validating and expanding on a public health model

Radhika Prakash-Asrani, Chris Bower, Chad Robichaux, Jesse T. Jacob et autres

OBJECTIVE: Validate a public health model identifying patients at high risk for carbapenem-resistant Enterobacterales (CRE) on admission and evaluate performance across a healthcare network. DESIGN: Retrospective case-control studies. PARTICIPANTS: Adults hospitalized with a clinical CRE culture within 3 days of admission (cases) …

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Blood Culture Use in Medical and Surgical Intensive Care Units and Wards

Valeria Fabre, Yea‐Jen Hsu, Karen C. Carroll, Alejandra Salinas et autres

Importance: Blood culture (BC) use benchmarks in US hospitals have not been defined. Objective: To characterize BC use in adult intensive care units (ICUs) and wards in US hospitals. Design, Setting, and Participants: A retrospective cross-sectional study of BC use in adult …

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Relationship between Hand Hygiene and MDRO Acquisition after Implementation of an Electronic Hand Hygiene Monitoring System

Radhika Prakash-Asrani, Jesse T. Jacob, Chris Bower, James P. Steinberg et autres

Background: Hand hygiene (HH) is fundamental to preventing the transmission of pathogens between patients. Unfortunately, adherence to HH is suboptimal and monitoring adherence is challenging. Electronic HH monitoring systems (EHHMS) are emerging potential solutions to increase the number of HH observations and …

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Identifying patients at high risk for carbapenem-resistant Enterobacterales carriage upon admission to acute-care hospitals

Jessica Howard‐Anderson, Radhika Prakash-Asrani, Chris Bower, Chad Robichaux et autres

Background: Prompt identification of patients colonized or infected with carbapenem-resistant Enterobacterales (CRE) upon admission can help ensure rapid initiation of infection prevention measures and may reduce intrafacility transmission of CRE. The Chicago CDC Prevention Epicenters Program previously created a CRE prediction model …

Evaluation of four environmental sampling methods for the recovery of multidrug-resistant organisms

Ahmed Babiker, Alex Page, Julia Van Riel, Eli Wilber et autres

Background: Environmental contamination is a major risk factor for multidrug-resistant organism (MDRO) exposure and transmission in the healthcare setting. Sponge-stick sampling methods have been developed and validated for MDRO epidemiological investigations, leading to their recommendation by public health agencies. However, similar bacteriological …

Carbapenem-Resistant enterobacterales in individuals with and without health care risk factors —Emerging infections program, United States, 2012-2015

Sandra N. Bulens, Hannah E. Reses, Uzma Ansari, Julian E. Grass et autres

BACKGROUND: Carbapenem-resistant Enterobacterales (CRE) are usually healthcare-associated but are also emerging in the community. METHODS: Active, population-based surveillance was conducted to identify case-patients with cultures positive for Enterobacterales not susceptible to a carbapenem (excluding ertapenem) and resistant to all third-generation cephalosporins tested …

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Clinical and Genomic Epidemiology of mcr-9 -Carrying Carbapenem-Resistant Enterobacterales Isolates in Metropolitan Atlanta, 2012 to 2017

Ahmed Babiker, Chris Bower, Joseph D. Lutgring, Robert A. Petit et autres

was not associated with significant phenotypic changes or clinical outcomes. However, given the increase in AMR and HMR gene content and potential clinical impact, continued genomic surveillance of multidrug-resistant organisms to monitor for emergence of AMR genes is warranted.

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