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Profil bibliographique

Lachlan J. Kelsey

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

46Publications signalées
484Citations signalées
1Affiliations récentes

Les institutions déclarées

Les domaines associés

Aortic aneurysm repair treatmentsCardiovascular Health and Disease PreventionPregnancy and preeclampsia studiesCoronary Interventions and DiagnosticsBirth, Development, and Health

Les publications récentes

Accès ouvert 2024 article OpenAlex

Feto-placental vascular structure and in silico haemodynamics: Of mice, rats, and human

Nikhilesh Bappoo, Yutthapong Tongpob, Jenny Myers, Emma Panting et autres

INTRODUCTION: The complex arborization of the feto-placental vasculature is crucial for optimal fetal nutrition, waste exchange and ultimately, development. Ethical and experimental limitations constrain research into the human placenta, hence experimental animal models such as mice and rats, are crucial to understand …

au, th, gb, nz (code pays fourni par la source)

13 citations Placenta
Accès ouvert 2024 article OpenAlex

Retinal and cerebral hemodynamics redistribute to favor thermoregulation in response to passive environmental heating and heated exercise in humans

Harrison T. Caddy, J. Criddle, Kristanti Wanito Wigati, Howard H. Carter et autres

Core temperature (TC) changes, alongside exercise, affect hemodynamic responses across different conduit and microvascular beds. This study investigated impacts of ecologically valid environmental heat and exercise exposures on cerebral, skin and retinal vascular responses by combining physiological assessments alongside computational fluid dynamics …

au, id (code pays fourni par la source)

1 citation Temperature
Accès ouvert 2024 article OpenAlex

Simulation of murine retinal hemodynamics in response to tail suspension

Harrison T. Caddy, Mitsunori Fujino, Ebrahim Vahabli, Valentina Voigt et autres

The etiology of spaceflight-associated neuro-ocular syndrome (SANS) remains unclear. Recent murine studies indicate there may be a link between the space environment and retinal endothelial dysfunction. Post-fixed control (N = 4) and 14-day tail-suspended (TS) (N = 4) mice eye samples were …

au, jp (code pays fourni par la source)

2 citations Computers in Biology and Medicine
Accès ouvert 2024 article OpenAlex

Modelling large scale artery haemodynamics from the heart to the eye in response to simulated microgravity

Harrison T. Caddy, Lachlan J. Kelsey, Louis P. Parker, Daniel J. Green et autres

We investigated variations in haemodynamics in response to simulated microgravity across a semi-subject-specific three-dimensional (3D) continuous arterial network connecting the heart to the eye using computational fluid dynamics (CFD) simulations. Using this model we simulated pulsatile blood flow in an upright Earth …

au, se (code pays fourni par la source)

13 citations npj Microgravity
Accès ouvert 2023 article OpenAlex

Comparison of computational fluid dynamics with transcranial Doppler ultrasound in response to physiological stimuli

Harrison T. Caddy, Hannah J. Thomas, Lachlan J. Kelsey, Kurt J. Smith et autres

Cerebrovascular haemodynamics are sensitive to multiple physiological stimuli that require synergistic response to maintain adequate perfusion. Understanding haemodynamic changes within cerebral arteries is important to inform how the brain regulates perfusion; however, methods for direct measurement of cerebral haemodynamics in these environments …

au, ca (code pays fourni par la source)

4 citations Biomechanics and Modeling in Mechanobiology
Accès ouvert 2023 preprint OpenAlex

A pilot study of pancreaticoduodenal artery aneurysms concomitant with coeliac artery stenosis: Using computational haemodynamics to better understand a rare disease

Dirk Blom, Rama Chidambaram, Harrison T. Caddy, Julian Soares et autres

Abstract Pancreaticoduodenal artery aneurysms have been associated with coeliac artery stenosis or occlusion. These aneurysms are rare, and their size may not be predictive of rupture risk. Wall shear stress has a potential role in the initiation, development and rupture of aneurysms. …

au (code pays fourni par la source)

0 citations Research Square
Accès ouvert 2023 article OpenAlex

Analysis of surface roughness in optical coherence elastography using a novel phantom

Rowan W. Sanderson, Harrison T. Caddy, Hina Ismail, Ken Y. Foo et autres

Compression optical coherence elastography (OCE) has shown promise in detecting diseases, such as breast cancer, based on changes in the elasticity of tissue. While the mechanical models used in OCE assume a flat surface, tissue typically exhibits surface topography that can lead …

au, pl (code pays fourni par la source)

13 citations Optics & Laser Technology
Accès ouvert 2023 preprint OpenAlex

Comparison of Computational Fluid Dynamics with Transcranial Doppler Ultrasound in Response to Physiological Stimuli

Harrison T. Caddy, Hannah J. Thomas, Lachlan J. Kelsey, Kurt J. Smith et autres

Abstract Cerebrovascular haemodynamics are sensitive to multiple physiological stimuli that require synergistic response to maintain adequate perfusion. Understanding haemodynamic changes within cerebral arteries is important to inform how the brain regulates perfusion, however methods for direct measurement of cerebral haemodynamics in these …

au, ca (code pays fourni par la source)

1 citation Research Square

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