Kasidis Phongkhun

Posaconazole Prophylaxis for the Prevention of Invasive Fungal Infections in Patients With Hematologic Malignancies: A Systematic Review and Meta‐Analysis

Kasidis Phongkhun, May Soe Thu, Nattiya Hirankarn, Arsa Thammahong

BACKGROUND: Invasive fungal infections (IFIs) pose a life-threatening risk to patients with hematologic malignancies undergoing intensive chemotherapy. Although posaconazole is widely used as a standard prophylactic agent, a comprehensive quantification of its efficacy, particularly regarding formulation-specific benefits and attributable mortality, is needed …

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Needs assessment of a pythiosis continuing professional development program

Surachai Leksuwankun, Rongpong Plongla, Nathanich Eamrurksiri, Pattama Torvorapanit et autres

BACKGROUND: Pythiosis is a rare disease with high mortality, with over 94% of cases reported from Thailand and India. Prompt diagnosis and surgery improves patient outcomes. Therefore, continuing professional development (CPD) is essential for early recognition. However, a needs assessment related to …

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374. A Multicenter Open-Label Single-Arm Clinical Trial of Combination Therapy of Surgery, Itraconazole, Doxycycline, and Azithromycin for Vascular Pythiosis

Kasama Manothummetha, Pattama Torvorapanit, Nuttapon Susaengrat, Navaporn Worasilchai et autres

Abstract Background Vascular pythiosis, caused by Pythium insidiosum, is a neglected, life-threatening condition which carried a 100% mortality rate, within 3 months, among patients with residual disease after surgery, regardless of antifungal treatment. Recently, Thai P. insidiosum isolates were found to susceptible …

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Attenuated immunogenicity of SARS-CoV-2 vaccines and risk factors in stem cell transplant recipients: a meta-analysis

Tanaporn Meejun, Karan Srisurapanont, Kasama Manothummetha, Achitpol Thongkam et autres

Immunogenicity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination is diminished in hematopoietic stem cell transplant (HSCT) recipients. To summarize current evidence and identify risk factors for attenuated responses, 5 electronic databases were searched since database inceptions through 12 January 2023 …

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Ribavirin treatment for respiratory syncytial virus infection in patients with haematologic malignancy and haematopoietic stem cell transplant recipients: a systematic review and meta-analysis

Kasama Manothummetha, Thanuthong Mongkolkaew, Punyot Tovichayathamrong, Rabhas Boonyawairote et autres

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Prevalence of Ocular Candidiasis and Candida Endophthalmitis in Patients With Candidemia: A Systematic Review and Meta-Analysis

Kasidis Phongkhun, Thananop L. Pothikamjorn, Karan Srisurapanont, Kasama Manothummetha et autres

BACKGROUND: Infectious diseases and ophthalmology professional societies have disagreed regarding ocular screening in patients with candidemia. We aimed to summarize the current evidence on the prevalence of ocular candidiasis (OC) and Candida endophthalmitis (CE) according to the standardized definitions. METHODS: A literature …

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Immunogenicity of SARS-CoV-2 vaccines in patients with multiple myeloma: a systematic review and meta-analysis

Nipat Chuleerarux, Kasama Manothummetha, Chatphatai Moonla, Anawin Sanguankeo et autres

Patients with multiple myeloma (MM) have a diminished immune response to coronavirus disease 2019 (COVID-19) vaccines. Risk factors for an impaired immune response are yet to be determined. We aimed to summarize the COVID-19 vaccine immunogenicity and to identify factors that influence …

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