Samuel Kaplan

Efficient Detection of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) from Exhaled Breath

Chaorui Duan, Luke Buerer, Jing Wang, Samuel Kaplan et autres

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Evaluating Closures of Fresh Fruit and Vegetable Vendors During the COVID-19 Pandemic: Methodology and Preliminary Results Using Omnidirectional Street View Imagery

Shahmir H. Ali, Valerie M Imbruce, Rienna G. Russo, Samuel Kaplan et autres

BACKGROUND: The COVID-19 pandemic has significantly disrupted the food retail environment. However, its impact on fresh fruit and vegetable vendors remains unclear; these are often smaller, more community centered, and may lack the financial infrastructure to withstand supply and demand changes induced …

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Evaluating Closures of Fresh Fruit and Vegetable Vendors During the COVID-19 Pandemic: Methodology and Preliminary Results Using Omnidirectional Street View Imagery (Preprint)

Shahmir H. Ali, Valerie M Imbruce, Rienna G. Russo, Samuel Kaplan et autres

BACKGROUND The COVID-19 pandemic has significantly disrupted the food retail environment. However, its impact on fresh fruit and vegetable vendors remains unclear; these are often smaller, more community centered, and may lack the financial infrastructure to withstand supply and demand changes induced …

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Predicting User Roles from Computer Logs Using Recurrent Neural Networks

Aaron R. Tuor, Samuel Kaplan, Brian Hutchinson, Nicole Nichols et autres

Network and other computer administrators typically have access to a rich set of logs tracking actions by users. However, they often lack metadata such as user role, age, and gender that can provide valuable context for users' actions. Inferring user attributes automatically …

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Engineered Erythrocytes As an Anti-Tumor Therapy through Induction of Apoptosis or Immune-Checkpoint Inhibition

Sivan Elloul, Claire E. Depew, Sujata Nerle, Tiffany Chen et autres

Abstract Rubius Therapeutics has built a platform for producing allogeneic Red Cell Therapeutics (RCTs), genetically modified red blood cells expanded ex vivo. RCTs maintain the expected properties of normal RBCs including immunoprivilege, long circulating half life and deformability. Using lentiviral gene delivery, …

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Listening to What the “Bug” Tells You

Samuel Kaplan

The College of Agriculture at Cornell University was virtually cost-free to residents of New York State and so the author decided to go there. Although there were laboratories in zoology, botany, and geology (and the author took them all), the microbiology laboratories …

Multiple Chromosomes

Chris Mackenzie, Samuel Kaplan, Madhusudan Choudhary

Some species of bacteria have more than one chromosome. Scientific dogma can be challenged at any time by the acquisition of new data or the reinterpretation of old data, but dogma is not easy to change. The word "plasmid" has drifted considerably …

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Transcriptome Response to Nitrosative Stress inRhodobacter sphaeroides2.4.1

Hiroyuki Arai, Jung Hyeob Roh, Jesus M. Eraso, Samuel Kaplan

The facultative photosynthetic bacterium Rhodobacter sphaeroides 2.4.1 has a nitric oxide-response transcriptional regulator, NnrR, and nitric oxide reductase (NOR), although it is incapable of denitrification. To investigate at the genomic level the physiological response to nitrosative stress of R. sphaeroides, the transcriptome …

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Revealing Linear Aggregates of Light Harvesting Antenna Proteins in Photosynthetic Membranes

Yufan He, Xiaohua Zeng, Saptarshi Mukherjee, Suneth P. Rajapaksha et autres

How light energy is harvested in a natural photosynthetic membrane through energy transfer is closely related to the stoichiometry and arrangement of light harvesting antenna proteins in the membrane. The specific photosynthetic architecture facilitates a rapid and efficient energy transfer among the …

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Half-Site DNA Sequence and Spacing Length Contributions to PrrA Binding to PrrA Site 2 of RSP3361 in Rhodobacter sphaeroides 2.4.1

Jesus M. Eraso, Samuel Kaplan

The consensus DNA binding sequence for PrrA, a global regulator in Rhodobacter sphaeroides 2.4.1, is poorly defined. We have performed mutational analysis of PrrA site 2, of the RSP3361 gene, to which PrrA binds in vitro (J. M. Eraso and S. Kaplan, …

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Regulation of Gene Expression by PrrA in Rhodobacter sphaeroides 2.4.1: Role of Polyamines and DNA Topology

Jesus M. Eraso, Samuel Kaplan

In the present study, we show in vitro binding of PrrA, a global regulator in Rhodobacter sphaeroides 2.4.1, to the PrrA site 2, within the RSP3361 locus. Specific binding, as shown by competition experiments, requires the phosphorylation of PrrA. The binding affinity …

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Revealing The Linear Aggregates Of Light Harvesting Antenna Proteins In Photosynthetic Membranes

Yufan He, Xiaohua Zeng, Saptarshi Mukherjee, Suneth P. Rajapaksha et autres

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