Maria Luisa D’Andrea

Dinutuximab beta with TEMIRI chemotherapy in relapsed/refractory neuroblastoma: Real-world insights into the open question of GD2 expression

Maria Antonietta De Ioris, Francesca Del Bufalo, Concetta Quintarelli, Valentina Bertaina et autres

INTRODUCTION: Prognosis of Relapsed/Refractory (R/R) neuroblastoma is still dismal. Chemoimmunotherapy has been reported to improve the response rate. PATIENTS AND METHODS: /day for 4 consecutive days. RESULTS: Twenty-five children received chemo-immunotherapy. Hematological toxicity was the most common adverse event. The best overall …

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Quantum Neural Networks in Magnetic Resonance Imaging: Advancing Diagnostic Precision Through Emerging Computational Paradigms

Enrico Rosa, Maria Vaccaro, Elisa Placidi, Maria Luisa D’Andrea et autres

Background: Quantum Neural Networks (QNNs) combine quantum computing and artificial intelligence to provide powerful solutions for high-dimensional data analysis. In magnetic resonance imaging (MRI), they address the challenges of advanced imaging sequences and data complexity, enabling faster optimization, enhanced feature extraction, and …

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Publisher Correction: GD2-targeting CAR T cells in high-risk neuroblastoma: a phase 1/2 trial

Franco Locatelli, Daria Pagliara, Maria Antonietta De Ioris, Marco Becilli et autres

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GD2-targeting CAR T cells in high-risk neuroblastoma: a phase 1/2 trial

Franco Locatelli, Daria Pagliara, Maria Antonietta De Ioris, Marco Becilli et autres

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131I-mIBG therapy in relapsed/refractory neuroblastoma: an old bridge to the future

Maria Antonietta De Ioris, Maria Felicia Villani, Francesca Del Bufalo, Claudio Altini et autres

BACKGROUND: I-mIBG) treatment as a tool to reduce tumour burden before novel immunotherapies is not defined. PATIENTS AND METHODS: ), supported by autologous haematopoietic stem cell rescue. The activity of the first administration was 444 MBq (12 mCi/kg), while the second dose …

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18F-FDG PET/CT: The turning point in eosinophilic fasciitis diagnosis in a pediatric patient

Elizabeth Katherine Anna Triumbari, Milena Pizzoferro, Maria Felicia Villani, Claudio Altini et autres

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Venetoclax plus cyclophosphamide and topotecan in heavily pre-treated relapsed metastatic neuroblastoma: a single center case series

Maria Antonietta De Ioris, Francesco Fabozzi, Francesca Del Bufalo, Giada Del Baldo et autres

The prognosis of relapsed/refractory (R/R) neuroblastoma (NB) is dismal, calling for new therapeutic strategies. Venetoclax (VEN) is a highly selective, potent, orally bioavailable, BCL-2 inhibitor small-molecule that showed a synergistic effect with cyclophosphamide and topotecan (Cy-Topo) in murine NB models. Our aim …

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The Pitfall of Ganglioneuroblastoma-Nodular Diagnosis: Clinical and Imaging Considerations over a Rare Bifocal Sporadic Case

Claudio Montante, Francesco Fabozzi, Maria Felicia Villani, Maria Luisa D’Andrea et autres

Neuroblastic tumors (NTs) represent the most common extracranial neoplasm occurring in childhood. Although ganglioneuroblastoma intermixed (GNBI) and ganglioneuroma (GN) are classified as very low-risk tumors, neuroblastoma (NB) and ganglioneuroblastoma-nodular (GNBN) may represent a serious risk to survival. Unfortunately, areas of GNBI and …

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Lung ultrasound findings in pediatric community-acquired pneumonia requiring surgical procedures: a two-center prospective study

Danilo Buonsenso, Paolo Tomà, Simona Scateni, Antonietta Curatola et autres

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Lung ultrasound: A useful additional tool in clinician's hands to identify pulmonary atelectasis in children with neuromuscular disease

Nicola Ullmann, Maria Luisa D’Andrea, Anna Gioachin, Bruno Papia et autres

INTRODUCTION AND OBJECTIVES: Patients with neuromuscular disease (NMD) are often exposed to ionizing radiations which could be reduced if a noninvasive and reliable diagnostic method is identified. The major aim of this study was to compare the use of chest X-ray (CXR) …

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Lung ultrasound as useful tool to diagnose pulmonary atelectasis in children affected by neuromuscular disease

Nicola Ullmann, Maria Luisa D’Andrea, Maria Beatrice Chiarini Testa, Paolo Tomà et autres

Introduction: Neuromuscular diseases are characterized by weakness of voluntary muscles which determines accumulation of secretions and atelectasis. As a consequence, an excess use of imaging exams is common. It is necessary to identify a reproducible, low cost and reliable diagnostic method to …

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Unusual Presentation of Relapse in Neuroblastoma

Maria Felicia Villani, Maria Luisa D’Andrea, Aurora Castellano, Milena Pizzoferro et autres

Neuroblastoma is the most common extracranial solid tumor in children and accounts for 8% to 10% of all childhood cancers. The spread of metastases is both lymphatic and hematogenous. Hematogenous route occurs most commonly in bone marrow and cortical bone; pancreatic metastases …

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