Accès ouvert
2026
article
OpenAlex
Oscar Horwath, Linnéa Corell, Junxiang Wan, Emma Hjalmarsson et autres
Regular exercise using assistive movement devices, such as running frames, has emerged as a promising strategy to improve cardiorespiratory fitness in individuals with cerebral palsy (CP). However, the molecular pathways underlying these adaptations remain poorly understood. Here, we examined a novel class …
se, us
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Accès ouvert
2026
article
OpenAlex
Johanna Flodin, Parsia Amiri, Stefan Markus Reitzner, Aisha Siddiqah Ahmed et autres
PURPOSE: Physical inactivity contributes to systemic inflammation and metabolic dysfunction. Neuromuscular electrical stimulation (NMES) offers an alternative to exercise for individuals unable to perform voluntary physical activity. This study investigated whether a single submaximal NMES session alters inflammation-related proteins, muscle-damage markers and …
se
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Accès ouvert
2026
article
OpenAlex
Stefan Markus Reitzner, Petter Brodin
Elite-level physical performance pushes the boundaries of human physical capacity. The immune system extensively contributes to this effort by its continuous maintenance of skeletal muscle and other active tissues, orchestrating post-exercise recovery, and as an important integrated sensor network throughout the body. …
se, gb
(code pays fourni par la source)
Accès ouvert
2025
preprint
OpenAlex
Eric B. Emanuelsson, Stefan Markus Reitzner, Allister Quizon, Jeffrey T. A. Burrows et autres
Abstract Regular exercise training is associated with systemic and tissue-specific performance and health benefits, yet long-term molecular adaptations in subcutaneous abdominal white adipose tissue (scWAT) remain unclear. We analyzed the resting scWAT transcriptome of 89 adults (35–50 years) who were long-term (>15 …
se, us
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Stefan Markus Reitzner, Jaromír Mikeš, Petter Brodin
Abstract Description Exercise training has the ability to modulate the immune system and its activation state, promoting recovery from disease and injury and re-balancing inflammatory processes in a cross-talk manner. However, it remains unclear how athletes prioritize and allocate energy resources between …
se
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Johanna Flodin, Stefan Markus Reitzner, Nida Mahmoud Hourani Soutari, Aisha Siddiqah Ahmed et autres
The immediate response to a 2-h neuromuscular electrical stimulation (NMES) session, delivered at an acceptable level of discomfort using NMES-pants, marginally increases the coagulative state, similar to what is observed after regular physical exercise. This change is not expected to significantly increase …
se
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Accès ouvert
2025
article
OpenAlex
Sebastian Edman, Linnéa Corell, William Hangasjärvi, Amelie von Finckenstein et autres
Brain-derived neurotrophic factor (BDNF) is a neurotrophin that plays a central role in neuronal health. BDNF exists in two primary isoforms, the mature form (mBDNF) and its precursor (proBDNF), with opposing downstream effects on neuronal function. The positive effect of exercise on …
se
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Annukka Saarensilta, Junyu Chen, Stefan Markus Reitzner, David A. Hart et autres
Deep venous thrombosis (DVT) and poor long-term patient outcomes frequently occur in patients with Achilles tendon rupture (ATR). Biomarkers for DVT and their possible relationship to long-term healing outcomes remain unexplored. To identify DVT biomarkers from proteomic profiles during the inflammatory and …
se, cn, ca
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Accès ouvert
2025
article
OpenAlex
Qi Chen, Binbin Zhao, Ziyang Tan, Gustav Hedberg et autres
Cancer is the leading cause of death from disease in children. Survival depends not only on surgery, cytostatic drugs, and radiation but also on systemic immune responses. Factors influencing these immune responses in children of different ages and tumor types are unknown. …
se, gb, us
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Abel Plaza‐Florido, Augusto Anguita‐Ruiz, Francisco José Esteban, Concepción María Aguilera et autres
This study pioneers the exploration into the effects of exercise on whole blood genome-wide DNA methylation patterns and its association with changes in transcriptome profiles in children with overweight/obesity. Exercise potentially impacts molecular pathways involved in metabolism and immune functions in children …
es, us, se, fi
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Accès ouvert
2024
preprint
OpenAlex
Sebastian Edman, Linnéa Corell, William Hangasjärvi, Amelie von Finckenstein et autres
Abstract Background Brain-derived neurotrophic factor (BDNF) is a neurotrophin that plays a central role in neuronal health. BDNF exists in two primary isoforms, the mature form (mBDNF) and its precursor (proBDNF), with opposing downstream effects on neuronal function. The positive effect of …
se
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Kristoffer Toldnes Cumming, Stefan Markus Reitzner, Marit Hanslien, Kenneth Skilnand et autres
The objective of this work was to investigate myonuclear permanence and transcriptional regulation as mechanisms for cellular muscle memory after strength training in humans. Twelve untrained men and women performed 10 weeks of unilateral elbow-flexor strength training followed by 16 weeks of …
no, se
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