Amisha Singh

Patterns of neoadjuvant chemotherapy (NAC) use in stage II-III bladder cancer: A California Cancer Registry (CCR) analysis.

Mamta Parikh, Frances B. Maguire, Amisha Singh, Nuen Tsang Yang et autres

647 Background: NAC followed by radical cystectomy (RC) improves survival compared to RC alone in patients with muscle invasive bladder cancer (MIBC), yet real-world uptake has lagged. Adjuvant chemotherapy (AC) for those not receiving NAC has been employed though survival benefit has …

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A pragmatic phase 2 trial of locally ablative therapy in oligo-progressive genitourinary (GU) tumors: LAYOVER

Amisha Singh, P. N. Lara, Nikhil N. Chatakondi, Kathleen Legarza et autres

TPS291 Background: Oligoprogressive disease (OPD) may represent an opportunity for locally ablative therapies to provide disease control in patients otherwise responding to systemic therapy. In GU malignancies, retrospective data suggest that ablating resistant clones in OPD sites with metastasis-directed therapies (MDT) such …

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Leveraging EfficientNet Architectures for Noise Robust Speech Recognition: An Empirical Study with AudioMNIST Dataset

Arpita Choudhury, Amisha Singh, Pinki Roy, Sivaji Bandyopadhyay

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A Comprehensive Approach to Stress Detection and Management Using Machine Learning, Deep Learning, and Chatbot Integration

Amisha Singh, Akshita Agarwal, Ajeet Kumar, Umang Rastogi et autres

In the modern era, mental health issues are increasing rapidly. That is why we need a strong and precise stress detection and management system to resolve the issue from the root. This research paper proposes an extensive approach combining machine computational power, …

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Phase I/II trial of BMS-986,205 and nivolumab as first line therapy in hepatocellular carcinoma

Jasmine C. Huynh, May Cho, Arta M. Monjazeb, Ebaa Al-Obeidi et autres

BACKGROUND: Indoleamine-2,3-dioxygenase (IDO) helps orchestrate immune suppression and checkpoint inhibitor resistance in hepatocellular carcinoma (HCC). BMS-986,205 is a novel oral drug that potently and selectively inhibits IDO. This Phase I/II study evaluated the safety and tolerability of BMS-986,205 in combination with nivolumab …

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Web App-based Multiple Diseases Detection Using Machine Learning: A Novel Approach

Amisha Singh, Anshu Kumar Dwivedi, Rupesh Kumar Mishra, Shashank Srivastav

The increasing prevalence of various diseases calls for the development of efficient and accurate disease detection systems. In this study, we propose a systematic approach for multiple disease detection using machine-learning techniques using a web-based application. The proposed method utilizes a dataset …

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Perioperative Immunotherapy in Muscle-Invasive Bladder Cancer

Amisha Singh, Appledene S. Osbourne, Vadim S. Koshkin

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Localized Synovial Sarcoma: A Population-Based Analysis of Treatment Patterns and Survival

Amisha Singh, Steven W. Thorpe, Theresa H.M. Keegan, Frances B. Maguire et autres

Purpose:Synovial sarcoma (SS) is a rare, high-grade soft tissue tumor that requires multidisciplinary and multimodal care with surgery, radiotherapy, and chemotherapy. We examined the impact of sociodemographic and clinical factors on treatment patterns and survival in localized SS patients. Methods:Adolescents and young …

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Case report: Treatment of metastatic dedifferentiated chondrosarcoma with pembrolizumab yields sustained complete response

Amisha Singh, Steven W. Thorpe, Morgan Darrow, Janai R. Carr

Dedifferentiated chondrosarcomas (DDCS) are aggressive tumors with poor outcomes. Treatment of localized DDCS is primarily surgical, though most patients present with unresectable or metastatic disease. Systemic treatment options for advanced DDCS are limited, and the benefits of chemotherapy in this patient population …

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Comparative Analysis of Rainfall Prediction Using Machine Learning and Deep Learning Techniques

Himanshi Chaudhary, Upendra Mishra, Arpita Gupta, Amisha Singh

Since the previous decade, weather has changed rapidly, raising concerns about unpredictable rains. Humidity, pressure, wind, and temperature affect rainfall. Thus, studying such characteristics to predict rainfall is intriguing. Machine learning and deep learning have simplified rainfall prediction, which is still under …

Factors associated with treatment given and survival outcomes in synovial sarcoma.

Amisha Singh, Steven W. Thorpe, Theresa H.M. Keegan, Frances B. Maguire et autres

e23539 Background: Synovial sarcoma (SS) is a rare, high-grade soft tissue tumor and often requires multidisciplinary care with different treatment modalities. However, information on treatment patterns, especially in patients with localized disease and impact on survival is currently lacking. Methods: Adolescents and …

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Phase I/II trial of BMS-986205 and nivolumab as first line therapy in hepatocellular carcinoma.

Jasmine Huynh, May Thet Cho, Arta M. Monjazeb, Kit Tam et autres

e16200 Background: Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide. Indoleamine-2,3-dioxygenase (IDO) is an intracellular enzyme expressed by HCC which helps to orchestrate immune suppression within the tumor microenvironment (TME) and may contribute to primary and acquired resistance of …

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