Monika Colombo

In silico modelling of aortic annuloplasty: hemodynamic assessment through in vitro experiments and in vivo MRI

Marta Zattoni, Luca Bontempi, Steffen Ringgaard, Giulia Luraghi et autres

• Implementation of the first animal-specific post-aortic annuloplasty aortic root model • 3D printed fabrication of resin pre- and post-aortic annuloplasty models and successful integration in flow experiments conducted in vitro • Fluid-structure interaction implementation of pre- and post-aortic annuloplasty in silico …

it, nl, dk (code pays fourni par la source)

A two-phase fluid structure interaction model of mucociliary clearance driven by cilium

Kavin Vishnu, Karupppasamy Subburaj, Monika Colombo

This study addresses the critical role of mucociliary clearance in respiratory health by developing a novel two-phase fluid-structure interaction model. The aim is to simulate realistic mucus transport driven by ciliary motion. Using direct cilia modeling and Carreau non-Newtonian rheology for the …

dk (code pays fourni par la source)

Idealized aortic annuloplasty FSI digital twin of 3D-printed phantoms with 4D-flow MRI comparison

Luca Bontempi, Marta Zattoni, Anna Ramella, Francesco Migliavacca et autres

BACKGROUND: Aortic annuloplasty, involving the implantation of an external ring around the aortic root to reduce annular dimensions, is a promising treatment for aortic valve insufficiency. However, its hemodynamic effects remain underexplored due to the absence of computational models validated by experimental …

it, dk (code pays fourni par la source)

A Two-Phase Fluid Structure Interaction Model of Mucociliary Clearance Driven by Cilium

Kavin Vishnu, Karupppasamy Subburaj, Monika Colombo

Abstract This study introduces a two-phase fluid-structure interaction (FSI) model of mucociliary clearance (MCC), utilizing direct cilia modeling and non-Newtonian Carreu rheology for the mucus layer (ML). A novel method for prescribing cilia beat patterns (CBP) was developed, enabling realistic motion replication …

dk (code pays fourni par la source)

Aortic annuloplasty FSI digital twin of 3D-printed phantoms with 4D-flow MRI comparison

Luca Bontempi, Marta Zattoni, Anna Ramella, Francesco Migliavacca et autres

Abstract Background Aortic annuloplasty, involving the implantation of an external ring around the aortic root to reduce annular dimensions, is a promising treatment for aortic valve insufficiency. However, its hemodynamic effects remain underexplored due to the absence of computational models validated by …

dk, nl, it (code pays fourni par la source)

Digital Twin of Aortic Annuloplasty: Hemodynamic Assessment Through in Vitro Experiments and in Vivo MRI

Marta Zattoni, Luca Bontempi, Steffen Ringgaard, Giulia Luraghi et autres

be, dk, it (code pays fourni par la source)

Real-time viscoelastic deformability cytometry: High-throughput mechanical phenotyping of liquid and solid biopsies

Mohammad Hossein Asghari, Sarah Duclos Ivetich, Mahmut Kamil Aslan, Morteza Aramesh et autres

In principle, the measurement of mechanical property differences between cancer cells and their benign counterparts enables the detection, diagnosis, and classification of diseases. Despite the existence of various mechanophenotyping methods, the ability to perform high-throughput single-cell deformability measurements on liquid and/or solid …

ch, se, dk (code pays fourni par la source)

Assessing the Effect of Magnetite Nanoflowers on Platelets in a Multiscale Approach in the Context of Thromboembolic Diseases

Monika Colombo, Yingchao Meng, Marie Poirier‐Quinot, Anne‐Laure Rollet et autres

Iron oxide magnetic nanoparticles have emerged as promising theranostic agents for the treatment of cardiovascular diseases. Using a multiscale approach, we investigated the interaction of 26.5 nm diameter multicore magnetite nanoflowers, recognized for being excellent nanoheaters and contrast agents in nanomedicine, with …

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Modelling lower-limb peripheral arterial disease using clinically available datasets: impact of inflow boundary conditions on hemodynamic indices for restenosis prediction

Federica Ninno, Claudio Chiastra, Monika Colombo, Alan Dardik et autres

gb, it, dk, us (code pays fourni par la source)

Assessing the effect of iron oxide magnetic nanoflowers on blood components in a multi-scale approach in the context of thromboembolic disease

Monika Colombo, Yingchao Meng, Marie Poirier‐Quinot, Anne‐Laure Rollet et autres

Iron oxide magnetic nanoparticles have emerged as promising theranostic agents for cardiovascular diseases. Using a multiscale approach, we investigate the interaction of 27 nm diameter multicore magnetite nanoflowers with blood components. Using flow cytometry and dynamic light scattering, we determine safe magnetite …

dk, ch, fr (code pays fourni par la source)

Modelling Lower-Limb Peripheral Arterial Disease Using Clinically Available Datasets: Impact of Inflow Boundary Conditions on Hemodynamic Indices for Restenosis Prediction

Federica Ninno, Claudio Chiastra, Monika Colombo, Alan Dardik et autres

gb, it, dk, us (code pays fourni par la source)

Correction: Real-time, smartphone-based processing of lateral flow assays for early failure detection and rapid testing workflows

Monika Colombo, Léonard Bezinge, Andres Rocha Tapia, Chih‐Jen Shih et autres

Correction for ‘Real-time, smartphone-based processing of lateral flow assays for early failure detection and rapid testing workflows’ by Monika Colombo et al. , Sens. Diagn. , 2023, 2 , 100–110, https://doi.org/10.1039/D2SD00197G.

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