Sarah Duclos Ivetich

Ultrahigh-Throughput Enrichment of Circulating Tumor Cells from Whole Blood

Yingchao Meng, Mahmut Kamil Aslan, Q. N. Xu, Sarah Duclos Ivetich et autres

Circulating tumor cells (CTCs) in peripheral blood serve as valuable indicators of cancer progression and important biomarkers for the early diagnosis and prognosis of the disease. Unfortunately, CTCs are typically present at extremely low concentrations, and the challenge of enriching and isolating …

ch, cn, us (code pays fourni par la source)

Real-time viscoelastic deformability cytometry: High-throughput mechanical phenotyping of liquid and solid biopsies

Mohammad H. Asghari, Sarah Duclos Ivetich, Mahmut Kamil Aslan, Morteza Aramesh et autres

In principle, the measurement of mechanical property differences between cancer cells and their benign counterparts enables the detection, diagnosis, and classification of diseases. Despite the existence of various mechanophenotyping methods, the ability to perform high-throughput single-cell deformability measurements on liquid and/or solid …

ch, se, dk (code pays fourni par la source)

Site-directed conjugation of single-stranded DNA to affinity proteins: quantifying the importance of conjugation strategy

Andres Rocha Tapia, Fabrice Abgottspon, Johan Nilvebrant, Per‐Åke Nygren et autres

Affinity protein-oligonucleotide conjugates are increasingly being explored as diagnostic and therapeutic tools. Despite growing interest, these probes are typically constructed using outdated, non-selective chemistries, and little has been done to investigate how conjugation to oligonucleotides influences the function of affinity proteins. Herein, …

ch, se, gb (code pays fourni par la source)

Microfluidic Flow Cytometry

Sarah Duclos Ivetich, Stavros Stavrakis, Andrew J. deMello

ch (code pays fourni par la source)

Viscoelastic Deformability Cytometry: Ultra-high Throughput Platform for Mechanical Phenotyping of Cells in Liquid and Solid Biopsies

Mohammad H. Asghari, Sarah Duclos Ivetich, Mahmut Kamil Aslan, Morteza Aramesh et autres

Abstract Due to the differences in mechanical properties between cancer cells and their benign counterparts, the mechanical characteristics of cells have emerged as a significant feature in diagnosing cancer. Consequently, measuring cell deformability as a means of mechanical phenotyping is promising for …

ch, se, dk (code pays fourni par la source)

Site-directed Conjugation of Single-Stranded DNA to Affinity Proteins: Quantifying the Importance of Conjugation Strategy

Andres Rocha Tapia, Fabrice Abgottspon, Johan Nilvebrant, Per‐Åke Nygren et autres

Affinity protein–oligonucleotide conjugates are increasingly being explored as diagnostic and therapeutic tools. Despite growing interest, these probes are typically constructed using outdated, non-selective chemistries, and little has been done to investigate how conjugation to oligonucleotides influences the function of affinity proteins. Herein, …

ch, se, gb (code pays fourni par la source)

Site-directed Conjugation of Single-Stranded DNA to Affinity Proteins: Quantifying the Importance of Conjugation Strategy

Andres Rocha Tapia, Fabrice Abgottspon, Johan Nilvebrant, Per‐Åke Nygren et autres

Affinity protein–oligonucleotide conjugates are increasingly being explored as diagnostic and therapeutic tools. Despite growing interest, these probes are typically constructed using outdated, non-selective chemistries, and little has been done to investigate how conjugation to oligonucleotides influences the function of affinity proteins. Herein, …

ch, se, gb (code pays fourni par la source)