Sarbjeet Niraula

Abstract Thu130: Gut Microbial Co-occurrence Network in Patients with Peripheral Artery Disease

Sarbjeet Niraula, Megan Alagna, Patrick Seed, Stefan Green et autres

Introduction: The human gut microbiome comprises a complex network of microorganisms and microbially-derived metabolites. The association of the gut microbiome with peripheral artery disease (PAD) is poorly understood. The goal of this study is to identify correlations of gut microbial markers with …

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Comparative study of sample storage conditions on gut dysbiosis in peripheral artery disease

Sarbjeet Niraula, Imadh Khan, Jonathan Jung, Spencer L. Stirewalt et autres

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Unusual Morphological Changes of a Novel Wrinkled Bacterium Isolated from the Rice Rhizosphere Under Nutrient Stress

Young Ryun Chung, Jung Eun Lee, Zubair Aslam, Eu Jin Chung et autres

Bacterial cell morphology might result from natural selection to gain a competitive advantage under environmentally stressful conditions such as nutrient limitation. In nutrient-limited conditions, a higher surface-to-volume ratio is crucial for cell survival because it allows for a more efficient exchange of …

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Abstract 2034: Gut Microbial Markers Associated With Clinical Features Of Peripheral Artery Disease

Sarbjeet Niraula, Spencer L. Stirewalt, Jonathan Jung, Megan Alagna et autres

Introduction: The human gut microbiome and microbe-derived metabolites are known to be associated with cardiovascular disease. However, their associations with lower extremity peripheral artery disease (PAD) are not well understood. The goal of this study is to identify specific gut microbial markers …

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Abstract 1156: Akkermansia (Strain BAA835) And The Microbial ADP-heptose Pathway Are Associated With Reduced Neointimal Hyperplasia After Arterial Injury

Karen J. Ho, Sarbjeet Niraula, Vivek Pamulapati, Jonathan Jung et autres

Introduction: Despite advances in surgical therapy for atherosclerosis, up to 50% of procedures such as balloon angioplasty, stenting, and bypass fail due to restenosis from neointimal hyperplasia, a cell proliferative process potentiated by inflammation. We hypothesized that neointimal hyperplasia is associated with …

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Gut Microbial Markers Associated With Clinical Features of Peripheral Artery Disease

Sarbjeet Niraula, Spencer L. Stirewalt, Jonathan Jung, Megan Alagna et autres

The human gut microbiome and microbe-derived metabolites are known to be associated with cardiovascular disease. However, their associations with lower extremity peripheral artery disease (PAD) are not well-understood. The goal of this study is to identify specific gut microbial markers associated with …

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Akkermansia (Strain BAA835) and the Microbial ADP-Heptose Pathway Are Associated With Reduced Neointimal Hyperplasia After Arterial Injury

Karen J. Ho, Sarbjeet Niraula, Vivek Pamulapati, Jonathan Jung et autres

Despite advances in surgical therapy for atherosclerosis, up to 50% of procedures such as balloon angioplasty, stenting, and bypass fail due to restenosis from neointimal hyperplasia, a cell proliferative process potentiated by inflammation. We hypothesized that neointimal hyperplasia is associated with a …

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Abstract 596: Microbe-derived Butyrate Activation Of Free Fatty Acid Receptor-3 Reduces Neointimal Hyperplasia After Arterial Injury By Regulating Immune Response Transcription Networks In Endothelial Cells

Jonathan Jung, Sarbjeet Niraula, James Du, Vivek Pamulapati et autres

Introduction: Microbe-derived butyrate has been shown to reduce neointimal hyperplasia after transluminal arterial injury, an effect that is dependent on free fatty acid receptor-3 (FFAR3). However, the mechanism by which FFAR3 affects the endothelial response to injury is not known. We hypothesize …

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Abstract 137: Identification Of Human Gut Microbial Markers In Patients With Peripheral Artery Disease Using Different Sample Preservation Methods

Sarbjeet Niraula, Spencer L. Stirewalt, Jonathan Jung, Jae Woo Jang et autres

Introduction: The gut microbiome is associated with cardiovascular diseases, but there is a paucity of microbial markers associated specifically with peripheral artery disease (PAD). We sought to identify gut microbial markers associated with PAD and to evaluate different sample preservation methods for …

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Microbe-derived Butyrate Activation of Free Fatty Acid Receptor-3 Reduces Neointimal Hyperplasia after Arterial Injury by Regulating Immune Response Transcription Networks in Endothelial Cells

Jonathan Jung, Sarbjeet Niraula, James Du, Vivek Pamulapati et autres

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Microbial co-occurrence network in the rhizosphere microbiome: its association with physicochemical properties and soybean yield at a regional scale

Sarbjeet Niraula, Meaghan Rose, Woo‐Suk Chang

Microbial communities in the rhizosphere play a crucial role in determining plant growth and crop yield. A few studies have been performed to evaluate the diversity and co-occurrence patterns of rhizosphere microbiomes in soybean (Glycine max) at a regional scale. Here, we …

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Unusual Morphological Changes of Rugositalea oryzae , A Novel Wrinkled Bacterium Isolated from The Rice Rhizosphere, Under Nutrient Stress

Young Ryun Chung, Jung Eun Lee, Zubair Aslam, Eu Jin Chung et autres

Abstract Bacterial cell morphology might result from natural selection to gain a competitive advantage under environmentally stressful conditions such as nutrient limitation. A bacterial strain YC6860 T isolated from the rhizosphere of rice ( Oryza sativa L.) showed pleomorphic behavior with smooth …

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