Shaohang Xu

Integration of proteogenomic analyses in esophageal squamous cell carcinoma

Guixue Hou, Shaohang Xu, Fang Zhao, Lijuan Duan et autres

Abstract Esophageal squamous cell carcinoma (ESCC) is still lack of clinically molecular subtyping and effective therapeutic strategies. Herein, a total of 46 paired tissue samples of esophageal squamous cell carcinoma (ESCC) were collected and subjected to a systematic proteogenomic evaluation. Consensus assessment …

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Pyoderma Gangrenosum Following Cesarean Section: A Case Report With Individualized Management

Shaohang Xu, Xiaojun Chen, Xiaoli Liu, Shuai Fu

Introduction: Pyoderma gangrenosum (PG) is a rare neutrophilic dermatosis characterized by rapidly progressive necrotizing skin ulcers. PG following cesarean section (CS) is extremely rare and frequently misdiagnosed as surgical site infection, leading to inappropriate debridement and disease exacerbation. We report a case …

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Coupling Machine Learning and Detrended Cumulative Drought Index for Lake-Area Prediction

Shaohang Xu, Zia Ahmed, Brian Alan Johnson, Ngai Weng Chan

Lakes play a crucial role in supplying water resources, regulating regional climates, and supporting ecosystems. However, they are increasingly threatened by recurrent droughts. This study focuses on the Mu Us Sandy Land, the fourth largest desert in China, and presents an approach …

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Hypobaric hypoxia disrupts brown adipose thermogenic function in mice via Plin2 upregulation

Yongfeng Hu, Jialin Zhao, Shaohang Xu, Jiayao Liu et autres

OBJECTIVE: High-altitude environments are characterized by hypobaric hypoxia and pose a significant physiological challenge. While obesity-related hypoxia is known to impair brown adipose tissue (BAT) function by suppressing lipolysis and thermogenesis, whether hypobaric hypoxia similarly compromises BAT function remains unclear. We hypothesize …

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Estimating soil moisture at farm scale with high spatial resolution: integrating remote sensing data, and machine learning

Di Wang, Shaohang Xu, Shuai Wang, Wenhui Liu et autres

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Author response for "Hypobaric hypoxia disrupts brown adipose thermogenic function in mice via Plin2 upregulation"

Yajie Hu, Jialin Zhao, Shaohang Xu, Jiayao Liu et autres

SETD7 exacerbates diabetic nephropathy through activating A2B receptor-JAK2/STAT3 pathway

Qiuyuan Huang, Wen Zhong, Ruoxue Chen, Shaohang Xu et autres

OBJECTIVE: Diabetic nephropathy (DN) is a leading cause of end-stage renal disease (ESRD), and there has been growing attention towards the role of epigenetics in its pathogenesis. This study aims to investigate the underlying mechanism by which SET domain-containing lysine methyltransferase 7 …

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Thoracoscopic surgical ablation for atrial fibrillation patients with functional regurgitation: the treatment strategy prioritizing atrial fibrillation

Yiren Sun, Zhengjie Wang, Shaohang Xu, Qi Tong et autres

BACKGROUND: Atrial fibrillation (AF) and functional regurgitation (FR) have complex interactions. This study investigated the interactions between thoracoscopic surgical ablation (TSA) and FR in patients with AF, to explore whether the strategy prioritizing AF can treat FR, thus avoiding additional valve surgeries. …

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Generative AI Revolutionizes Educational Coding: Empirical Validation of Chinese LLMs’ Performance Leap

Xiaoqing Zhang, Shaohang Xu, Zengyi Yu

Transesophageal echocardiography, computed tomography, or both when assessing the efficacy of different left atrial appendage closure techniques?

Oumar Abdel Mahamoud, Shaohang Xu, Yongjun Qian

We read with great interest the article by Petersen and colleagues.1Petersen J. Böning H. Yildirim S. et al.Efficacy of four different left atrial appendage closure techniques during cardiac surgery—a transesophageal echocardiography follow-up study.J Thorac Cardiovasc Surg Tech. 2024; XX: XXhttps://doi.org/10.1016/j.xjtc.2024.05.007Abstract Full Text …

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[Exploration of the clinical transformation application of the artificial intelligence diagnosis system for bladder cancer based on cystoscopy].

Sai Wu, Xun Chen, Guibin Hong, Shaohang Xu et autres

This study aims to explore the possibility and bottleneck of clinical translation for an artificial intelligence (AI) diagnosis system for bladder cancer based on cystoscopy.We retrospectively collected videos of 101 bladder cancer patients from January to November 2023, at Sun Yat-sen Memorial …

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Estimating Soil Moisture at Farm Scale with High Spatial Resolution: Integrating Remote Sensing Data, and Machine Learning

Di Wang, Shaohang Xu, Shuai Wang, Wenhui Liu et autres