2026
article
OpenAlex
Greta Catani, Luz Divina Juez, Juan M O´Connor, Antonino Spinelli et autres
INTRODUCTION: Early-onset gastrointestinal (GI) cancers, defined as those diagnosed before the age of 50, are increasing worldwide, whereas the incidence of late-onset GI cancers has stabilized or declined. These trends highlight the need to better understand age-related differences in disease biology and …
es, it
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Accès ouvert
2026
article
OpenAlex
Greta Catani, Juan Manuel O’Connor, Antonino Spinelli, José Perea
PURPOSE: Early-onset colorectal cancer (EOCRC), defined as colorectal cancer diagnosed before the age of 50 years, is increasing worldwide and represents a growing clinical and public health challenge. Whether EOCRC constitutes a biologically distinct entity remains uncertain, and current diagnostic and therapeutic …
ar, it, es
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Accès ouvert
2025
article
OpenAlex
Greta Catani, Oriol Mirallas, Vicky Sánchez-Pérez, Paolo Nucíforo et autres
Immune checkpoint inhibitors have revolutionized the treatment of solid tumors; however, their clinical efficacy remains limited to a subset of patients. Novel immunotherapy agents are being investigated in phase I clinical trials, with an increasing focus on biomarker selection strategies to optimize …
es, ar, us, br
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2025
article
OpenAlex
Alessandro Audisio, Chiara Gallio, Vaneja Velenik, Hélène Meillat et autres
Importance: This was a clinical study of total neoadjuvant therapy (TNT) for rectal cancer. Objective: To assess the use and outcomes of TNT in routine practice. Design, Setting, and Participants: This international, multicenter study was conducted at 61 centers across 21 countries …
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Accès ouvert
2025
article
OpenAlex
D. Morchón Araujo, Greta Catani, Oriol Mirallas, G. Pretelli et autres
Immunotherapy has significantly changed the treatment paradigm for solid tumors, with immune checkpoint inhibitors now established in the management of many malignancies. Despite initial success, durable responses remain limited to a subset of patients, often less than 30%, due to both intrinsic …
es, ar
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Accès ouvert
2025
article
OpenAlex
Berenice Freile, Andrés Rodríguez, Greta Catani, Marcos Bortz et autres
Gastroesophageal cancers are among the most prevalent cancers globally and represent the third leading cause of cancer-related mortality worldwide. Surgical resection remains the primary curative approach for localised and locally advanced stages, but its effectiveness is limited for locally advanced diseases, evidenced …
ar
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2025
article
OpenAlex
Marcos Bortz, Federico Waisberg, Federico Losco, Andrés Rodríguez et autres
e21031 Background: Mentorship is a valuable aspect of professional development in oncology. It has been associated with an increase in job satisfaction, self-confidence and career success, while contributing to the reduction of burnout. To date, there are no published examples of the …
ar
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Accès ouvert
2025
article
OpenAlex
Andrés Rodríguez, Greta Catani, Oscar Andriani, Gerardo Arroyo et autres
Los tumores neuroendocrinos (TNEs) representan un grupo heterogéneo de neoplasias, caracterizadas por una amplia variabilidad en su comportamiento clínico, biológico y molecular. Esta diversidad, tanto a nivel de presentación como de respuesta a los tratamientos, representa un desafío significativo en la práctica …
ar, uy, br, co, es, pr
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Accès ouvert
2025
article
OpenAlex
Greta Catani, Stéfano Kim, Federico Waisberg, Diego Enrico et autres
Background/Objectives: The BRAF-mutation is a poor prognostic factor in colorectal cancer (CRC). There is a need for real-world data in low-middle-income countries regarding clinical characteristics, outcomes, and treatment strategies. This study aims to describe progression-free survival (PFS) and in the first- and …
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Accès ouvert
2025
preprint
OpenAlex
Greta Catani, Stéfano Kim, Federico Waisberg, Diego Enrico et autres
Background/Objectives: BRAF-mutation is a poor prognostic factor in colorectal cancer (CRC). There is a need for real-world data in low-middle-income countries regarding clinical characteristics, outcomes, and treatment strategies. This study aims to describe progression free survival (PFS) and overall survival (OS) in …
ar, uy
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2025
article
OpenAlex
Greta Catani, Federico Esteso, Luisina Bruno, Andrés Rodríguez et autres
Metastatic colorectal cancer (mCRC) represents a significant global public health challenge. The identification of biomarkers such as microsatellite instability (MSI) and the status of mismatch repair (MMR) proteins, among others, provides crucial information for guiding therapeutic decisions and predicting prognosis. Immune checkpoint …
ar
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Accès ouvert
2024
article
OpenAlex
Greta Catani, Federico Waisberg, Luisina Bruno, Marcos Bortz et autres
Introducción: El cáncer colorrectal (CCR) en adultos jóvenes es una entidad cada vez más prevalente y se estima que en la próxima década 1 de cada 4 pacientes sea menor de 50 años. En nuestro país existen pocos datos de este subgrupo …
ar
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