Koki Sugimoto

Alleviating Effect of Echinacea Purpurea Petal Water Extract on Symptoms of Ovalbumin-Induced Allergic Rhinitis in Mice

Koki Sugimoto, Hirofumi Arai, Anuu Zorig, Ayaka Abe et autres

Echinacea purpurea petal extract (EPPE) may attenuate type I allergic symptoms. Dietary EPPE decreased nasal scratching and sneezing in allergic rhinitis model mice. This decrease may be attributed to the decrease in serum immunoglobulin E levels and the potential suppression of chemical …

jp (code pays fourni par la source)

Structural Analysis of Acidic Glycosphingolipids in the Adductor Muscle of the Japanese Giant Scallop (Patinopecten yessoensis)

S. Sonoda, Saki Itonori, Mutsumi Sugita, Ayako Higashino et autres

Structural analysis of glycosphingolipids provides novel insights into organismal classification and reveals conserved functional roles that transcend taxonomic boundaries. To elucidate the structural characteristics of acidic glycosphingolipids (AGLs) in the adductor muscle of the Japanese giant scallop (Patinopecten yessoensis), AGLs were isolated …

jp (code pays fourni par la source)

Lysophosphatidylcholine, rich in n‐3 polyunsaturated fatty acids, inhibits leukotriene production by mouse mast cells

Mikako Takasugi, Hirofumi Arai, Koki Sugimoto, Tadahiro Tsushima et autres

Abstract In fishery industries, large amounts of byproducts are discarded during processing; therefore, their use as a source of n‐3 polyunsaturated fatty acids (PUFAs) is beneficial. In this study, we evaluated the potential anti‐allergic effect of lysophosphatidylcholine (Lyso‐PtdCho) derived from squid skin …

jp (code pays fourni par la source)

Bioconversion and Metabolic Fate of the n-1 Polyunsaturated Fatty Acids, 6,9,12,15- Hexadecatetraenoic (C16:4 n-1) and 8,11,14,17- Octadecatetraenoic (C18:4 n-1) Acids, in HepG2 Cells

Koki Sugimoto, Hideto Nishiguchi, Ryôta Hosomi, Toshifumi Tanizaki et autres

Fish oil contains not only major fatty acids with double bonds at the n-3, n-6, n-7, and n-9 positions but also those with a double bond at the n-1 position, such as 6,9,12,15-hexadecatetraenoic acid (C16:4 n-1; HDTA). However, intracellular bioconversion and metabolic …

jp, nl, ch (code pays fourni par la source)

Bioconversion and Metabolic Fate of the n-1 Polyunsaturated Fatty Acids, 6,9,12,15- Hexadecatetraenoic (C16:4 n-1) and 8,11,14,17- Octadecatetraenoic (C18:4 n-1) Acids, in HepG2 Cells

Koki Sugimoto, Hideto Nishiguchi, Ryôta Hosomi, Toshifumi Tanizaki et autres

Fish oil contains not only major fatty acids with double bonds at the n-3, n-6, n-7, and n-9 positions but also those with a double bond at the n-1 position, such as 6,9,12,15-hexadecatetraenoic acid (C16:4 n-1; HDTA). However, intracellular bioconversion and metabolic …

Scallop ceramide 2-aminoethylphosphonate is more effective than egg yolk sphingomyelin in improving cholesterol metabolism in obese/type II diabetic KK-A mice

Koki Sugimoto, Ryôta Hosomi, Saki Itonori, Munehiro Yoshida et autres

• Ceramide 2-aminoethylphosphonate (CAEP) has a high serum lipid improving effect. • Dietary CAEP reduced serum triacylglycerol level via lowering fatty acid synthesis. • CAEP intake reduced body’s cholesterol level via decreasing cholesterol absorption. • CAEP can be used as a health-promoting …

jp (code pays fourni par la source)

Effects of Daily Consumption of Scallop Oil Prepared from Internal Organs of Japanese Giant Scallop (Patinopecten yessoensis) on Serum Lipid Composition and Its Safety: A Randomized, Double-blind, Placebo-controlled, Parallel Group Comparison Study

Koki Sugimoto, Mie Nishimura, Naohito Ito, Ryôta Hosomi et autres

Scallop oil (SCO) prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis) contains eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and phospholipids (PL). It was previously shown that SCO consumption improves cholesterol and triacylglycerols (TG) contents in mice. The present …

jp, nl (code pays fourni par la source)

Dietary Bamboo Charcoal Decreased Visceral Adipose Tissue Weight by Enhancing Fecal Lipid Excretions in Mice with High-Fat Diet-Induced Obesity

Koki Sugimoto, Taiki Shinagawa, K. Kuroki, S. B. Toma et autres

Bamboo charcoal (BC) powder is prepared from thick bamboo stems via dry distillation and is often used for food coloring. Due to the unique structure of the micropores in bamboo stems, BC powder also serves as an indigestible carrier to prevent the …

jp (code pays fourni par la source)

Studies on the Safety and Health-Promoting Function of Edible Oil Prepared from the Internal Organs of the Japanese Giant Scallop (Patinopecten yessoensis) [論文要旨及び審査の要旨]

Koki Sugimoto

Studies on the Safety and Health-Promoting Function of Edible Oil Prepared from the Internal Organs of the Japanese Giant Scallop (Patinopecten yessoensis)

Koki Sugimoto

Dietary scallop oil prepared from the internal organs of Japanese giant scallop (Patinopecten yessoensis) improved mite allergen-induced atopic dermatitis-like symptoms on the dorsal skin of NC/Nga mice

Koki Sugimoto, Nozomi Hagihara, Ryôta Hosomi, Munehiro Yoshida et autres

This study aimed to investigate the effects of scallop oil (SCO) on atopic dermatitis (AD)-like symptoms induced by mite allergens in the dorsal and ear skins of NC/Nga mice compared to those of refined corn oil and krill oil (KO). SCO, rich …

jp (code pays fourni par la source)

Chronic Treatment with Metformin Has No Disrupting Effect on the Hepatic Circadian Clock in Mice

Nazmul Hasan, Koki Sugimoto, Koki Yamada, Jun‐ichi Morishige et autres

Background and Objectives: The antidiabetic agent metformin is known to activate AMP-activated protein kinase (AMPK) in various tissues. Because AMPK can modulate intracellular circadian clocks through regulating the stability of clock components, a single dose of metformin has been reported to affect …

jp (code pays fourni par la source)