Effects of Daily Consumption of Scallop Oil Prepared from Internal Organs of Japanese Giant Scallop (Patinopecten yessoensis) on Serum Lipid Composition and Its Safety: A Randomized, Double-blind, Placebo-controlled, Parallel Group Comparison Study
Rattachement africain : jp, nl. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
Scallop oil (SCO) prepared from the internal organs of the Japanese giant scallop (Patinopecten yessoensis) contains eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA), and phospholipids (PL). It was previously shown that SCO consumption improves cholesterol and triacylglycerols (TG) contents in mice. The present study demonstrated the effects of daily SCO consumption (1.2 g/day, containing 376 mg of EPA, 63 mg of DHA, and 150 mg of PL) for 12 weeks in human subjects. In this randomized, doubleblind, placebo-controlled, parallel group comparison study, 70 Japanese subjects with serum TG levels ≥120 but < 200 mg/dL were recruited and randomly assigned to the SCO or placebo group. All subjects ingested six capsules per day for 12 weeks. We conducted medical interviews, body composition measurements, vital sign examinations, and blood sampling at weeks 0 (baseline), 4, 8, and 12, and measured peripheral blood flow at weeks 0 and 12. In the case of subjects with higher serum TG levels, SCO consumption decreased the changes in serum TG and malondialdehyde-low density lipoprotein (MDA-LDL) levels compared with the placebo group. Safety assessment revealed no medically significant changes due to continuous SCO consumption. The findings indicate that 1.2 g/day of SCO consumption may be beneficial for reducing serum TG and MDA-LDL levels in persons with higher TG levels.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé, mais le titre doit être comparé manuellement.
- Titre Crossref
- Effects of Daily Consumption of Scallop Oil Prepared from Internal Organs of Japanese Giant Scallop (<i>Patinopecten yessoensis</i>) on Serum Lipid Composition and Its Safety: A Randomized, Double-blind, Placebo-controlled, Parallel Group Comparison Study
- Date Crossref
- 01/01/2024
- Éditeur
- Japan Oil Chemists' Society
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Toyo University pays non établi dans la noticeUniversité ou école supérieure
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Food & Nutrition pays non établi dans la noticeInstitution
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Hokkaido Information University Department of Medical Management and Informatics pays non établi dans la noticeUniversité ou école supérieure
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Kansai University Department of Life Science and Biotechnology pays non établi dans la noticeUniversité ou école supérieure
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Faculty of Food and Nutritional Sciences pays non établi dans la noticeUniversité ou école supérieure
Toyo University, Food & Nutrition et Department of Medical Management and Informatics — Hokkaido Information University, avec 2 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.