Hadeil Morsi

National Audit of Long‐Term Real‐World Outcomes of Berotralstat Use in UK Patients With Hereditary Angioedema

Haggar Elbashir, Anthony D. Dorr, Manisha Ahuja, Lorena Lorenzo et autres

The data that support the findings of this study are available from the corresponding author upon reasonable request. Appendix S1: all70086-sup-0001-AppendixS1.docx. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any …

gb (code pays fourni par la source)

A multi-centre UK-based survey on angioedema secondary to acquired C1 inhibitor deficiency

Hadeil Morsi, Aarnoud Huissoon, Alexandros Grammatikos, Andrew Whyte et autres

BACKGROUND: Acquired angioedema due to C1-inhibitor deficiency (AAE-C1-INH) is very rare compared to its prototype, hereditary angioedema. An updated characterization of the AAE-C1-INH cohort in the UK is required to inform management. OBJECTIVES: To describe the disease burden of AAE-C1-INH, long-term prophylaxis …

gb, us, au (code pays fourni par la source)

SARS-CoV-2 Vaccine Responses in Individuals with Antibody Deficiency: Findings from the COV-AD Study

Adrian Shields, Sian Faustini, Harriet J. Hill, Saly Al‐Taei et autres

BACKGROUND: Vaccination prevents severe morbidity and mortality from COVID-19 in the general population. The immunogenicity and efficacy of SARS-CoV-2 vaccines in patients with antibody deficiency is poorly understood. OBJECTIVES: COVID-19 in patients with antibody deficiency (COV-AD) is a multi-site UK study that …

gb, hr, us (code pays fourni par la source)

A Multicentre UK-Based Audit on Acquired C1 Inhibitor Deficiency 2021

Hadeil Morsi, Alexandros Grammatikos, Cathal Steele, Catherine Stroud et autres

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Outcomes following SARS-CoV-2 infection in patients with primary and secondary immunodeficiency in the UK

Adrian Shields, Ariharan Anantharachagan, Gururaj Arumugakani, Kenneth F. Baker et autres

In March 2020, the United Kingdom Primary Immunodeficiency Network (UKPIN) established a registry of cases to collate the outcomes of individuals with PID and SID following SARS-CoV-2 infection and treatment. A total of 310 cases of SARS-CoV-2 infection in individuals with PID …

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Outcomes Following SARS-CoV-2 Infection in Patients With Primary and Secondary Immunodeficiency in The United Kingdom

Adrian Shields, Ariharan Anantharachagan, Gururaj Arumugakani, Kenneth F. Baker et autres

gb, au, ca, om, Zambie (code pays fourni par la source)

COVID-19 in patients with primary and secondary immunodeficiency: The United Kingdom experience

Adrian Shields, Siobhan O. Burns, Sinisa Savic, Alex Richter et autres

gb, ca (code pays fourni par la source)

A near miss on blaming the heart: a rare case of Adrenocortical carcinoma with thrombus extension into right atrium and Cushing syndrome

Hadeil Morsi, Mohamed Eisa, L. Goodwin, P J Flegg et autres

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

An insight on antibody-mediated immune-metabolism in inflammation and homeostasis: the role of Fc gamma receptors in regulation of indolemaine 2,3 dioxygenase activity in dendritic cells (IRM9P.460)

Hadeil Morsi, Fabián Salazar, Amir M. Ghaemmaghami

Abstract Indoleamine2, 3-dioxygenase (IDO) is a key immune-modulatory enzyme in Tryptophan catabolism that is highly expressed by Dendritic cells (DCs). Notably, DCs are the main mediators of Fc-dependent anti-inflammatory effects of Intravenous Immunoglobulins (IVIgs) as well as Immune Complexes (ICs)-induced inflammation. Hence, …

gb, Soudan (code pays fourni par la source)

Antibody Response of Swine to Leptospira canicola and Leptospira icterohaemorrhagiae

Hadeil Morsi, G. P. Shibley, H. L. Strother

SUMMARY Serum samples collected from swine 7 months after vaccination with Leptospira icterohaemorrhagiae and Leptospira canicola bacterin contained protective antibodies, as determined by hamster protection test. The samples had low macroscopic agglutination (ma) titers. After swine were exposed to virulent leptospires, the …

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Renal Leptospirosis: Exposure of Vaccinated and Nonvaccinated Swine to Leptospira icterohaemorrhagiae and Leptospira canicola

G. P. Shibley, Hadeil Morsi, H. L. Strother, Molly S. Clark

SUMMARY Serotest-negative swine were vaccinated with inactivated Leptospira icterohaemorrhagiae and Leptospira canicola bacterin. Seven months later, vaccinated and nonvaccinated control swine were exposed to viable L. icterohaemorrhagiae and L. canicola. With L. canicola, Leptospiremia was detected in 100% of the control swine …

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