Kurando Utagawa

Sensory nerves regulate bone homeostasis in response to mechanical unloading or reloading: evidence from a spaceflight experiment and ground-based mechanical unloading models

Shohei Tsujino, Hiroki Ochi, Risa Okada, Daisuke Kamimura et autres

Mechanical loading is crucial for maintaining bone mass, and understanding how bone remodels in response to mechanical loading is essential for treating musculoskeletal disorders. Recently, sensory nerves inside bone were identified as mechanical regulators of bone homeostasis. However, how the structure and …

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Clinical Outcomes and Mechanical Complications After Adult Spinal Deformity Surgery in Patients Aged 80 Years or Older: A Propensity Score-Matched Comparative Study

Kai Inoue, Atsuyuki Kawabata, Jun Hashimoto, Takayuki Motoyoshi et autres

Study DesignRetrospective cohort study.ObjectivesTo compare outcomes after adult spinal deformity (ASD) surgery between patients aged 80 years or older and those younger than 80 years.MethodsWe retrospectively reviewed patients aged 65 years or older with ASD who underwent long-segment posterior corrective fusion. Patients …

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Revisiting hemostasis strategy: the impact of excessive monopolar electrocautery on periosteal-driven spinal fusion

Duby Okonkwo, Atsuyuki Kawabata, Rachel M. McKee, Kurando Utagawa et autres

BACKGROUND CONTEXT: The common surgical approach in posterior spinal fusion (PSF) conflicts with basic principles of bone repair and may lead to high failure rates. In recent years, experimental data has shown that the periosteum plays an indispensable role in fracture bone …

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Hydroxyapatite/collagen composite graft for anterior cervical discectomy and fusion: a comparison with Iliac crest bone graft

Yu Matsukura, Takashi Hirai, Motonori Hashimoto, Kentaro Sakaeda et autres

BACKGROUND: The iliac crest bone graft (ICBG) has been traditionally used as the gold standard for anterior cervical discectomy and fusion (ACDF). However, the complication rate associated with harvesting the tricortical ICBG is significantly high. Thus, this study aimed to investigate the …

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Early Cases of Single-Level Cervical Total Disc Replacement in Japan-Short-Term Safety Assessment Using Registry Data

Kurando Utagawa, Toshitaka Yoshii, Hiroshi Taneichi, Kentaro Yamada et autres

Introduction: was approved in Japan in 2017. To ensure effective surgical outcomes with TDR, the Japanese TDR guideline was established before its clinical use, and a registry system was developed to monitor the safety of early cases in Japan. This study assessed …

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Factors Associated With Nonunion After Cervical Fusion Surgery

Hiroyuki Inose, Takuya Takahashi, Yu Matsukura, Jun Hashimoto et autres

Background Bony fusion is a critical factor in the outcome of cervical spinal fusion surgery. While several factors have been proposed to affect bony fusion, their relative importance remains unclear. This study aimed to investigate the factors associated with bony fusion after …

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Novel Technique of Anterior Foraminotomy Based on Augmented Reality with Computed Tomography Navigation System: A Case Report

Takashi Hirai, Satoru Egawa, Kenichiro Sakai, Hiroaki Onuma et autres

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The lower Osteotomy Level is Associated With Decreased Revision Surgery Due to Mechanical Complications After Three-Column Osteotomy in Patients With Adult Spinal Deformity: A Multi-Institutional Retrospective Study

Atsuyuki Kawabata, Kenichiro Sakai, Kentaro Yamada, Kurando Utagawa et autres

Study design A multi-institutional retrospective study. Objectives To investigate risk factors of mechanical failure in three-column osteotomy (3COs) in patients with adult spinal deformity (ASD), focusing on the osteotomy level. Methods We retrospectively reviewed 111 patients with ASD who underwent 3COs with …

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Effect of vitamin D deficiency on surgical outcomes of degenerative cervical myelopathy

Hiroyuki Inose, Takuya Takahashi, Yu Matsukura, Jun Hashimoto et autres

Background: Due to its association with bone metabolic status and muscle strength/mass, vitamin D deficiency has the potential to affect neurological symptom recovery after surgery for degenerative cervical myelopathy (DCM). However, few studies have investigated the effects of vitamin D deficiency (serum …

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Three-dimensional visualization of neural networks inside bone by Osteo-DISCO protocol and alteration of bone remodeling by surgical nerve ablation

Kurando Utagawa, Takaei Shin, Hironori Yamada, Hiroki Ochi et autres

Bone is one of the largest organ systems in humans and is considered to regulate whole-body homeostasis in cooperation with other organs. We have previously reported that a sympathetic or sensory nervous system inside bone regulates bone homeostasis. However, the detailed regulatory …

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Development and testing of a new application for measuring motion at the cervical spine

Koji Fujita, Kana Matsuo, Takafumi Koyama, Kurando Utagawa et autres

BACKGROUND: Cervical myelopathy is a progressive disease, and early detection and treatment contribute to prognosis. Evaluation of cervical intervertebral instability by simple X-ray is used in clinical setting and the information about instability is important to understand the cause of myelopathy, but …

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Intraosseous Aggressive Schwannoma in the Lumbar Spine: A Case Report

Takashi Hirai, Toshitaka Yoshii, Hiroyuki Inose, Yu Matsukura et autres

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