Factors Associated With Nonunion After Cervical Fusion Surgery
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Le résumé fourni par la source
Background Bony fusion is a critical factor in the outcome of cervical spinal fusion surgery. While several factors have been proposed to affect bony fusion, their relative importance remains unclear. This study aimed to investigate the factors associated with bony fusion after cervical spinal fusion surgery. Methods We retrospectively evaluated the significance of the various factors on bone fusion after cervical fusion surgery. Then, multivariate logistic regression analyses were performed to determine the independent factors associated with bony fusion. A receiver operating characteristic (ROC) analysis was performed to evaluate the cutoff threshold. Results This study included a total of 52 patients with a mean age of 64 years. Among them, 28 (54%) were male, and 39 (75.0%) achieved bony fusion. The multivariate logistic regression analysis showed that preoperative intact parathyroid hormone (PTH) levels (odds ratio, 1.04; 95% confidence interval, 1.01-1.08; p-value = 0.02) and hemoglobin A1c (HbA1c) levels (odds ratio, 2.87; 95% confidence interval, 1.07-8.74; p-value = 0.04) were significant factors associated with bony fusion after cervical fusion surgery. The optimum cutoff values of intact PTH and HbA1c were 63.5 pg/mL and 6.2%, respectively. Conclusions This study identified preoperative intact PTH and HbA1c as significant factors associated with bony fusion after cervical fusion surgery. These biomarkers can be used to identify patients at higher risk of nonunion to optimize patient conditions and guide preoperative and postoperative management strategies.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- Factors Associated With Nonunion After Cervical Fusion Surgery
- Date Crossref
- 20/12/2023
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Tokyo Medical and Dental University . Department of Orthopedics pays non établi dans la noticeUniversité ou école supérieure
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Jichi Medical University pays non établi dans la noticeUniversité ou école supérieure
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Social Insurance Saitama Chuo Hospital pays non établi dans la noticeÉtablissement de santé
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Jichi Medical University Saitama Medical Center pays non établi dans la noticeÉtablissement de santé
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Dokkyo Medical University Department of Orthopedics pays non établi dans la noticeUniversité ou école supérieure
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Saitama Medical University pays non établi dans la noticeUniversité ou école supérieure
. Department of Orthopedics — Tokyo Medical and Dental University, Jichi Medical University et Social Insurance Saitama Chuo Hospital, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.