Accès ouvert
2025
article
OpenAlex
Abigail Cheever, Hunter G. Lindsay, Chloe Kang, Mackenzie Hansen et autres
Introduction: Chimeric antigen receptor (CAR) T cells have recently become an important treatment for hematological cancers by efficiently eliminating B cells. B cell depleting CAR T cells are also in clinical trials for their use in treating severe autoimmune diseases and have …
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Accès ouvert
2024
article
OpenAlex
Jay R. Radke, Javier Ochoa‐Repáraz, Jamee Nixon, Sajal Acharya et autres
The annual meeting for the Intermountain Branch was held in April 2024 on the campus of Brigham Young University. There were 127 branch members from Utah, Idaho, and Nevada who attended the meeting and were composed of undergraduate students, graduate or medical …
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2024
conference-abstract
OpenAlex
Abiagil Cheever, Hunter G. Lindsay, Mackenzie Hansen, Chloe Kang et autres
Abstract Introduction: Chronic inflammation often leads to cancer, and many autoimmune diseases lead to a significantly increased risk of developing cancer. Though many autoimmune diseases, like Graves’ Disease (GD), don’t have treatments that address this risk. Chimeric antigen receptor (CAR) T cells …
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2024
conference-abstract
OpenAlex
Mackenzie Hansen, Qin Yuan Zhou, Yoko S. DeRose, Magdalena Kovacsovics et autres
Abstract Introduction: To better understand the immune microenvironment in non-small cell lung cancer (NSCLC), we evaluated immune cell populations within the tumor parenchyma and their interaction at the periphery of the tumors at different stages of disease. Methods: 27 whole tumor slides …
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Accès ouvert
2023
article
OpenAlex
Mackenzie Hansen, Abigail Cheever, K. Scott Weber, Kim Leslie O'Neill
Graves' disease (GD) is a thyroid-specific autoimmune disease with a high prevalence worldwide. The disease is primarily mediated by B cells, which produce autoantibodies against the thyroid-stimulating hormone receptor (TSHR), chronically stimulating it and leading to high levels of thyroid hormones in …
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