Isabel Roca Bielsa

Histopathologic Features of Cutaneous Plexiform Schwannomas in Neurofibromatosis Type 2‐Related Schwannomatosis: Analysis of a Series of 19 Cases

Adrià Plana‐Pla, Ariadna Quer, Cristina Carrato, Elisabeth Castellanos et autres

IMPORTANCE: Neurofibromatosis type 2 (NF2)-related schwannomatosis is a genetic disease characterized by multiple tumors involving the nervous system. Some patients develop cutaneous schwannomas with characteristic histologic features that, if recognized, may have diagnostic and prognostic value. OBJECTIVE: To describe the clinical and …

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Joint EANM/SNMMI procedural guideline for paediatric bone hybrid imaging with 99mTc-labelled radiopharmaceuticals and [18F]fluoride

Julian M.M. Rogasch, Reza Vali, Lise Borgwardt, Lisa J. States et autres

The purpose of these guidelines is to offer nuclear medicine teams a framework that could prove helpful in daily practice. The guidelines include information related to the indications, acquisition, processing and interpretation of bone scans in children, focusing primarily on 99m Tc-labelled …

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[Artículo traducido] Redefiniendo la retirada de omalizumab en pacientes con urticaria crónica espontánea: el valor de la optimización y de los biomarcadores de recurrencia

Joan Ceravalls, Ana Maria Giménez‐Arnau, Vicente Expósito‐Serrano, Natalia Fernández Chico et autres

BACKGROUND: Patients with chronic spontaneous urticaria frequently relapse after discontinuing omalizumab and require its reintroduction. Although prior optimization might reduce recurrences, there is scarce evidence on this issue. Moreover, predictors of relapse have been identified in non-optimized patients before suspension. METHODS: We …

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Redefining Omalizumab Discontinuation in Chronic Spontaneous Urticaria: The Value of Optimization and Predictive Factors of Relapse. A 52-Week Multicenter Study

Joan Ceravalls, Ana Maria Giménez‐Arnau, Vicente Expósito‐Serrano, Natalia Fernández Chico et autres

Patients with chronic spontaneous urticaria frequently relapse after discontinuing omalizumab and require its reintroduction. Although prior optimization might reduce recurrences, there is scarce evidence on this issue. Moreover, predictors of relapse have been identified in non-optimized patients before suspension. We conducted a …

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Refractory Generalised Morphea in Association with Reactive Hypereosinophil Syndrome Successfully Managed with Abatacept

Juan José Lluch‐Galcerá, Ivette Casafont-Sole, Blanca Xicoy, Ariadna Quer et autres

Dear Editor, Morphea, or localised scleroderma, is an inflammatory condition causing sclerosis of skin and subcutaneous tissues. Its generalised variant can be associated with systemic complications.[1] While eosinophilia is observed in morphea,[2] it rarely reaches levels indicating potential organ damage. Among the …

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Predictive Factors and Optimization of Omalizumab in Chronic Spontaneous Urticaria: A Multicenter Study of 257 Patients

Joan Ceravalls, A.M. Giménez-Arnau, Vicente Expósito‐Serrano, Natalia Fernández Chico et autres

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Real-world evaluation of the effectiveness and safety of dupilumab in bullous pemphigoid: an ambispective multicentre case series

Nidia Planella‐Fontanillas, Xavier Bosch‐Amate, Alicia Jimenez‐Anton, Carlos Moreno‐Vílchez et autres

BACKGROUND: Bullous pemphigoid (BP) affects elderly individuals with multiple comorbidities, making conventional treatments unsuitable. OBJECTIVES: Evaluate the effectiveness and safety of dupilumab in the treatment of BP. METHODS: A multicentre ambispective cohort study was conducted across 34 hospitals. Patients with BP treated …

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Peripheral blood T-cell modulation by omalizumab in chronic urticaria patients

Cristina Esquinas López, Nathalie Depreux, Isabel Roca Bielsa, Albert Roger et autres

Background: Chronic spontaneous urticaria (CSU) is a highly prevalent and difficult to manage cutaneous disease characterized by the presence of recurrent urticaria, angioedema, or both, for a period of 6 weeks or longer. One of the biological treatments used for patients with …

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The evidence-based role of catecholaminergic PET tracers in Neuroblastoma. A systematic review and a head-to-head comparison with mIBG scintigraphy

Arnoldo Piccardo, Giorgio Treglia, Francesco Fiz, Zvi Bar‐Sever et autres

Abstract Background Molecular imaging is pivotal in staging and response assessment of children with neuroblastoma (NB). [123I]-metaiodobenzylguanidine (mIBG) is the standard imaging method; however, it is characterised by low spatial resolution, time-consuming acquisition procedures and difficult interpretation. Many PET catecholaminergic radiotracers have …

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Refractory IgA pemphigus successfully managed with adalimumab as monotherapy

Carmen Alcoverro, Eugeni Prat, Manel Martinez‐Molina, Isabel Roca Bielsa et autres

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White hyperkeratotic plaque in a patient with infantile spasms

Verónica Mora‐Fernández, Adrià Plana‐Pla, Ariadna Quer, Ignacio Blanco et autres

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Verrucous epidermal nevus as a manifestation of a type 2 mosaic PTEN mutation in Cowden syndrome

Adrià Plana‐Pla, Laura Condal, Ane Jaka, Ignacio Blanco et autres

Linear Cowden nevus, also known as linear PTEN nevus, is a type of epidermal nevus, first described in 2007, which is seen in patients with PTEN hamartoma tumor syndrome. It is considered to be a type 2 form of segmental mosaicism, and …

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