Hara Afaloniati

Effect of dietary inclusion of Sea – buckthorn (Hippophae rhamnoides) on health and productivity of mink

Anna Maria Iatrou, Anastasia Iatrou, Maria Kyritsi, Hara Afaloniati et autres

The objective of this study was to assess the effect of Sea-buckthorn (SB) on mink productivity and health. The experiment lasted 10 months and was divided into reproductive and growing periods. 100 brown female mink were randomly assigned to two groups (n=50): …

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Suppression of chemically induced mammary cancer by early-life oral administration of cholera toxin in mice is associated with aberrant regulation of Bmp and Notch signaling pathways

Dimitrios G Argyris, Maria P. Markaki, Hara Afaloniati, George S. Karagiannis et autres

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Peri‐weaning cholera toxin consumption suppresses chemically‐induced carcinogenesis in mice

Hara Afaloniati, Georgios Aindelis, Katerina Spyridopoulou, Maria K. Lagou et autres

Gastrointestinal bacteria are known to have an impact on local and systemic immunity, and consequently either promote or suppress cancer development. Following the notion that perinatal bacterial exposure might confer immune system competency for life, we investigated whether early-life administration of cholera-toxin …

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Inhibition of γδ-TcR or IL17a Reduces T-Cell and Neutrophil Infiltration after Ischemia/Reperfusion Injury in Mouse Liver

Saant Al Mogrampi, Christina Boumpoureka, Hara Afaloniati, Maria K. Lagou et autres

Neutrophil and T-cell recruitment contribute to hepatic ischemia/reperfusion injury. The initial inflammatory response is orchestrated by Kupffer cells and liver sinusoid endothelial cells. However, other cell types, including γδ-Τ cells, seem to be key mediators in further inflammatory cell recruitment and proinflammatory …

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Effects of Dietary Supplementation of Spirulina platensis on the Immune System, Intestinal Bacterial Microbiome and Skin Traits of Mink

Anna Maria Iatrou, Sofia Michailidou, Georgios Α. Papadopoulos, Hara Afaloniati et autres

The impact of dietary inclusion of Spirulina platensis on the immune system, intestinal microbiome and skin of mink was investigated. Forty-eight animals were equally separated into four groups. Groups B and D were control animals, while groups A and C had their …

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Romidepsin hepatocellular carcinoma suppression in mice is associated with deregulated gene expression of bone morphogenetic protein and Notch signaling pathway components

Hara Afaloniati, Theofilos Poutahidis, Alexander E Giakoustidis, Athanasios Apostolos Gargavanis et autres

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HDAC1/2 Inhibitor Romidepsin Suppresses DEN-Induced Hepatocellular Carcinogenesis in Mice

Hara Afaloniati, Katerina Angelopoulou, Alexander E Giakoustidis, Alexandros Hardas et autres

BACKGROUND: Hepatocellular carcinoma (HCC) is a frequently diagnosed cancer and a leading cause of cancer-related death worldwide. Its rapid progression, combined with the limited treatment options at late stages, imposes the need for early detection and aggressive intervention. Based on the knowledge …

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HDAC1/2 Inhibitor Romidepsin Suppresses DEN-Induced Hepatocellular Carcinogenesis in Mice

Hara Afaloniati, Katerina Angelopoulou, Alexandros E. Giakoustidis, Alexandros Hardas et autres

Hara Afaloniati,1 Katerina Angelopoulou,1 Alexander Giakoustidis,2 Alexandros Hardas,3 Athanasios Pseftogas,4 Kali Makedou,5 Athanasios Gargavanis,2 Thomas Goulopoulos,2 Stavros Iliadis,5 Vasileios Papadopoulos,2 Apostolos Papalois,6 George Mosialos,4 Theofilos Poutahidis,3 Dimitrios Giakoustidis2 1Laboratory of Biochemistry and Toxicology, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle …

Inflammation-induced colon cancer in uPA-deficient mice is associated with a deregulated expression of Notch signaling pathway components

Hara Afaloniati, George S. Karagiannis, Emmanouel Karavanis, Theophano A. Psarra et autres

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Inflammation-driven colon neoplasmatogenesis in uPA-deficient mice is associated with an increased expression of Runx transcriptional regulators

Hara Afaloniati, George S. Karagiannis, Alexandros Hardas, Theofilos Poutahidis et autres

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BMP pathway suppression is an early event in inflammation-driven colon neoplasmatogenesis of uPA-deficient mice

George S. Karagiannis, Hara Afaloniati, Elisavet Karamanavi, Theofilos Poutahidis et autres

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