Katerina Angelopoulou

Morphometric analysis of the thymic epithelial cell network using integrated and orthogonal digital pathology approaches

Maria K. Lagou, Maria P. Markaki, Stepan Vodopyanov, Dimitrios G Argyris et autres

The thymus, a central organ for T cell development, lacks standardized pathology methods to assess its structure and function. Most studies rely on flow cytometry, which profiles thymic cell populations but offers limited spatial insight into tissue organization. This gap restricts our …

us, gr, gb (code pays fourni par la source)

Effect of dietary inclusion of Sea – buckthorn (Hippophae rhamnoides) on health and productivity of mink

Anna Maria Iatrou, Anastasia Iatrou, Maria Kyritsi, Hara Afaloniati et autres

The objective of this study was to assess the effect of Sea-buckthorn (SB) on mink productivity and health. The experiment lasted 10 months and was divided into reproductive and growing periods. 100 brown female mink were randomly assigned to two groups (n=50): …

gr (code pays fourni par la source)

Suppression of chemically induced mammary cancer by early-life oral administration of cholera toxin in mice is associated with aberrant regulation of Bmp and Notch signaling pathways

Dimitrios G Argyris, Maria P. Markaki, Hara Afaloniati, George S. Karagiannis et autres

us, gr (code pays fourni par la source)

Peri‐weaning cholera toxin consumption suppresses chemically‐induced carcinogenesis in mice

Hara Afaloniati, Georgios Aindelis, Katerina Spyridopoulou, Maria K. Lagou et autres

Gastrointestinal bacteria are known to have an impact on local and systemic immunity, and consequently either promote or suppress cancer development. Following the notion that perinatal bacterial exposure might confer immune system competency for life, we investigated whether early-life administration of cholera-toxin …

gr, us (code pays fourni par la source)

Kinetics of endogenous thymic regeneration following chemotherapy-induced involution

Maria K. Lagou, Randall S. Carpenter, Dimitra P. Anastasiadou, Alexandros Hardas et autres

Abstract The thymus is a primary lymphoid organ where T cell development occurs. Besides the naturally transpiring age-dependent involution, the thymus also undergoes acute involution from cytotoxic stimuli. Establishing thymic regeneration strategies would, thus, be immensely critical for pediatric cancer and transplantation …

us, gb, mx, gr (code pays fourni par la source)

Inhibition of γδ-TcR or IL17a Reduces T-Cell and Neutrophil Infiltration after Ischemia/Reperfusion Injury in Mouse Liver

Saant Al Mogrampi, Christina Boumpoureka, Hara Afaloniati, Maria K. Lagou et autres

Neutrophil and T-cell recruitment contribute to hepatic ischemia/reperfusion injury. The initial inflammatory response is orchestrated by Kupffer cells and liver sinusoid endothelial cells. However, other cell types, including γδ-Τ cells, seem to be key mediators in further inflammatory cell recruitment and proinflammatory …

gr, gb, cy (code pays fourni par la source)

Effects of Dietary Supplementation of Spirulina platensis on the Immune System, Intestinal Bacterial Microbiome and Skin Traits of Mink

Anna Maria Iatrou, Sofia Michailidou, Georgios Α. Papadopoulos, Hara Afaloniati et autres

The impact of dietary inclusion of Spirulina platensis on the immune system, intestinal microbiome and skin of mink was investigated. Forty-eight animals were equally separated into four groups. Groups B and D were control animals, while groups A and C had their …

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Romidepsin hepatocellular carcinoma suppression in mice is associated with deregulated gene expression of bone morphogenetic protein and Notch signaling pathway components

Hara Afaloniati, Theofilos Poutahidis, Alexander E Giakoustidis, Athanasios Apostolos Gargavanis et autres

gr (code pays fourni par la source)

HDAC1/2 Inhibitor Romidepsin Suppresses DEN-Induced Hepatocellular Carcinogenesis in Mice

Hara Afaloniati, Katerina Angelopoulou, Alexander E Giakoustidis, Alexandros Hardas et autres

BACKGROUND: Hepatocellular carcinoma (HCC) is a frequently diagnosed cancer and a leading cause of cancer-related death worldwide. Its rapid progression, combined with the limited treatment options at late stages, imposes the need for early detection and aggressive intervention. Based on the knowledge …

gr (code pays fourni par la source)

HDAC1/2 Inhibitor Romidepsin Suppresses DEN-Induced Hepatocellular Carcinogenesis in Mice

Hara Afaloniati, Katerina Angelopoulou, Alexandros E. Giakoustidis, Alexandros Hardas et autres

Hara Afaloniati,1 Katerina Angelopoulou,1 Alexander Giakoustidis,2 Alexandros Hardas,3 Athanasios Pseftogas,4 Kali Makedou,5 Athanasios Gargavanis,2 Thomas Goulopoulos,2 Stavros Iliadis,5 Vasileios Papadopoulos,2 Apostolos Papalois,6 George Mosialos,4 Theofilos Poutahidis,3 Dimitrios Giakoustidis2 1Laboratory of Biochemistry and Toxicology, School of Veterinary Medicine, Faculty of Health Sciences, Aristotle …

Effect of crocin on antioxidant gene expression, fibrinolytic parameters, redox status and blood biochemistry in nicotinamide-streptozotocin-induced diabetic rats

Ioannis Margaritis, Katerina Angelopoulou, Sophia N. Lavrentiadou, Ilias C. Mavrovouniotis et autres

Abstract Background Diabetes is regarded as an epidemiological threat for the twenty-first century. Phytochemicals with known pharmaceutical properties have gained interest in the field of alleviating secondary complications of diseases. Such a substance is crocin, a basic constituent of saffron (Crocus sativus). …

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Successful inhibition of tumour growth in DEN-induced hepatocarcinogenesis in C57BL/6 mice with HDAC1/2 inhibitor Romidepsin

Alexandros E. Giakoustidis, Paola Andreani, Theofilos Poutahidis, Katerina Angelopoulou et autres

gb, gr (code pays fourni par la source)