Ivana Goić-Barišić

Antimicrobial Resistance and Virulence of Acinetobacter baumannii; A Whole-Genome Sequencing Perspective from a Croatian Intensive Care Unit

Marija Čavka, Marija Kvesić, Ana Maravić, Mia Dželalija et autres

Background/Objectives: Acinetobacter baumannii is a major cause of infections in Intensive Care Units (ICUs), driving mortality through high-level antimicrobial resistance. This study utilized whole-genome sequencing (WGS) to evaluate the phenotypic, genotypic and virulence features of carbapenem-resistant A. baumannii (CRAB), which has caused …

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Phenotypic and Whole-Genome Sequencing-Based Profiling of Antimicrobial Resistance and Virulence in Pseudomonas aeruginosa Isolated from Patients with Ventilator-Associated Pneumonia and Ventilator-Associated Tracheobronchitis in a Croatian Intensive Care Unit

Marija Čavka, Marija Kvesić, Ana Maravić, Mia Dželalija et autres

Background/Objectives: Pseudomonas aeruginosa is one of the leading causes of ventilator-associated pneumonia (VAP) and ventilator-associated tracheobronchitis (VAT), with a worldwide spread of difficult-to-treat high-risk clones. This study aimed to investigate the virulence potential and to characterize phenotypic and genotypic antimicrobial resistance (AMR) …

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Cerium, copper, gallium, manganese and silver substituted hydroxyapatite: cytotoxicity and antibacterial activity toward multidrug-resistant clinical isolates

Tomislav Ivanković, Andreja Žužić, Virginia Alessandra Gobbo, Blanka Dadic et autres

• Evaluation of antibacterial activity of HAp doped with Ag + , Ce 3+ , Cu 2+ , Ga 3+ , Mn 2+ . • All HAp materials are non-cytotoxic, except Cu-doped HAp. • Ag + -doped HAp showed significant antibacterial activity …

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Unravelling the Persistence of the Rare Serovar Salmonella Mikawasima in a Hospital Setting: A Whole-Genome Sequencing Study

Ivana Ferenčak, Ana Gverić Grginić, Tajana Juzbašić, Irena Tabain et autres

Salmonella Mikawasima is a rare, mainly environmental serovar. In 2020, an outbreak was observed in neonatal and maternal wards of the University Hospital of Split and was established as an endemic until the end of 2024. Using whole-genome sequencing, this study aimed …

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Phenotypic and Whole-Genome Sequencing-Based Profiling of Antimicrobial Resistance and Virulence in Campylobacter spp. Isolated from Human Stool in a Croatian University Hospital

Luka Katic, Ivana Ferenčak, Ana Gverić-Grginić, Ivana Goić-Barišić et autres

Campylobacter spp. is a leading cause of community-acquired gastroenteritis, with rising antimicrobial resistance (AMR) posing a significant public health challenge. This study aimed to characterize the genomic basis of resistance and virulence in Campylobacter spp. isolated from human stool at the University …

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Comparison of AccuPower Diarrhea V1&V2 RT-PCR to a Chromatographic Immunoassay for Detecting Viral Pathogens from Human Diarrheal Stool Specimens

Luka Katic, Boris Mihaljević, Marijo Pirija, Ivana Goić-Barišić et autres

Viruses are a frequent cause of self-limited diarrhea, with more severe outcomes in immunocompromised patients. This study aimed to compare the performance of Real-Time RT-PCR to chromatographic immunoassays (CIAs) for detecting the major gastrointestinal viruses in human stool. This study was conducted …

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Molecular characterization and survival of extended-spectrum β-lactamase-producing clinical strains of Klebsiella pneumoniae isolated in Mostar, Bosnia and Herzegovina.

Tanja Žugić Petrović, Marija Tonkić, Ana Maravić, Mia Dželalija et autres

The aim of this retrospective study was to investigate the molecular characteristics and survival ability of clinical isolates of extended-spectrum β-lactamase (ESBL)-producing strains of Klebsiella pneumoniae (K. pneumoniae) in a hospital setting. ESBL-producing K. pneumoniae clinical isolates were collected from hospitalized patients …

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Phenotypic and Molecular Characterization of a Hospital Outbreak Clonal Lineage of Salmonella enterica Subspecies enterica serovar Mikawasima Containing bla TEM-1B and bla SHV-2 That Emerged on a Neonatal Ward, During the COVID-19 Pandemic

Anita Novak, Mia Dželalija, Ivana Goić-Barišić, Ana Kovačić et autres

Nontyphoid salmonella can cause severe infections in newborns and is therefore declared a pathogen of major health significance at this age. The aim of the study was molecular and antimicrobial characterization of β-lactamase-producing Salmonella Mikawasima outbreak clone on a Neonatal ward, University …

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Molecular characterisation of colistin and carbapenem-resistant clinical isolates of Acinetobacter baumannii from Southeast Europe

Ivana Goić-Barišić, Martina Šeruga Musić, Marina Drčelić, Semra Tunçbilek et autres

OBJECTIVES: To characterise 11 colistin- and carbapenem-resistant Acinetobacter baumannii isolates recently emerging in hospital settings. METHODS: A. baumannii isolates were collected from hospitalised patients under colistin treatment in three countries of Southeast Europe: Turkey, Croatia, and Bosnia and Herzegovina. Isolates were identified …

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Molecular characterization of colistin resistance genes in a high-risk ST101/KPC-2 clone of Klebsiella pneumoniae in a University Hospital of Split, Croatia

Žana Rubić, Marko Jelić, Silvija Šoprek, Maja Tarabene et autres

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A Rare Presentation of Genitourinary Tuberculosis Mimicking Abdominal Tumor

Ivana Goić-Barišić

Genital tuberculosis is a rare and unexpected disease in European countries including Croatia. Diagnosis of female genital tract tuberculosis is challenging and is rarely pin-pointed by clinical symptoms because of their low specificity. The authors decided to present a case of genitourinary …

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Antibakterijski učinak preparata „Sanosil super25“ na višestruko rezistentne bakterije Acinetobacter baumannii i Klebsiella pneumoniae

Ana Kovačić, Jasna Hrenović, Ivana Goić-Barišić, Miroslav Barišić

Višestruko rezistentne bakterije, uzročnici hospitalnih infekcija, kao što su Acinetobacter baumannii i Klebsiella pneumoniae, predstavljaju globalni problem 21. stoljeća. Osobito zabrinjava sve učestalija pojava otpornosti ovih mikroorganizama na komercijalno dostupne dezinficijense. Cilj našeg istraživanja bio je utvrditi učinkovitost dezinfekcije proizvoda „Sanosil super25“, …

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