Anita Novak

Antimicrobial Resistance and Virulence of Acinetobacter baumannii; A Whole-Genome Sequencing Perspective from a Croatian Intensive Care Unit

Marija Čavka, Marija Kvesić, Ana Maravić, Mia Dželalija et autres

Background/Objectives: Acinetobacter baumannii is a major cause of infections in Intensive Care Units (ICUs), driving mortality through high-level antimicrobial resistance. This study utilized whole-genome sequencing (WGS) to evaluate the phenotypic, genotypic and virulence features of carbapenem-resistant A. baumannii (CRAB), which has caused …

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Phenotypic and Whole-Genome Sequencing-Based Profiling of Antimicrobial Resistance and Virulence in Pseudomonas aeruginosa Isolated from Patients with Ventilator-Associated Pneumonia and Ventilator-Associated Tracheobronchitis in a Croatian Intensive Care Unit

Marija Čavka, Marija Kvesić, Ana Maravić, Mia Dželalija et autres

Background/Objectives: Pseudomonas aeruginosa is one of the leading causes of ventilator-associated pneumonia (VAP) and ventilator-associated tracheobronchitis (VAT), with a worldwide spread of difficult-to-treat high-risk clones. This study aimed to investigate the virulence potential and to characterize phenotypic and genotypic antimicrobial resistance (AMR) …

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Restoration, but not maintenance of sinus rhythm during amiodarone pretreatment predicts the success of pulmonary vein isolation in persistent atrial fibrillation

Dóra Krányák, Anita Novak, Noémi Pataky, A Benak et autres

Abstract Introduction Restoration and maintenance of sinus rhythm (SR) in the months before pulmonary vein isolation (PVI) by antiarrhythmic drug (AAD) therapy may lead to a better outcome in persistent atrial fibrillation (AF). Amiodarone is the only AAD that has been shown …

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Unravelling the Persistence of the Rare Serovar Salmonella Mikawasima in a Hospital Setting: A Whole-Genome Sequencing Study

Ivana Ferenčak, Ana Gverić Grginić, Tajana Juzbašić, Irena Tabain et autres

Salmonella Mikawasima is a rare, mainly environmental serovar. In 2020, an outbreak was observed in neonatal and maternal wards of the University Hospital of Split and was established as an endemic until the end of 2024. Using whole-genome sequencing, this study aimed …

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Phenotypic and Whole-Genome Sequencing-Based Profiling of Antimicrobial Resistance and Virulence in Campylobacter spp. Isolated from Human Stool in a Croatian University Hospital

Luka Katic, Ivana Ferenčak, Ana Gverić-Grginić, Ivana Goić-Barišić et autres

Campylobacter spp. is a leading cause of community-acquired gastroenteritis, with rising antimicrobial resistance (AMR) posing a significant public health challenge. This study aimed to characterize the genomic basis of resistance and virulence in Campylobacter spp. isolated from human stool at the University …

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Comparison of AccuPower Diarrhea V1&V2 RT-PCR to a Chromatographic Immunoassay for Detecting Viral Pathogens from Human Diarrheal Stool Specimens

Luka Katic, Boris Mihaljević, Marijo Pirija, Ivana Goić-Barišić et autres

Viruses are a frequent cause of self-limited diarrhea, with more severe outcomes in immunocompromised patients. This study aimed to compare the performance of Real-Time RT-PCR to chromatographic immunoassays (CIAs) for detecting the major gastrointestinal viruses in human stool. This study was conducted …

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Antimicrobial resistance surveillance of Bacteroides fragilis isolated from blood cultures, Europe, 2022 (ReSuBacfrag)

Michæl Bühl, Torgny Sunnerhagen, Olivier Join‐Lambert, Trefor Morris et autres

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Prolonged watery diarrhea and malnutrition caused by Aliarcobacter butzleri (formerly Arcobacter butzleri): the first pediatric case in Croatia and a literature review

Anita Novak, Marija Vuko-Tokić, Vanda Žitko, Marija Tonkić

isolated from stool sample in a 4-year old boy in Croatia, along with other clinical reports in literature, highlights the importance of standardisation and improvement of microbiological analysis, especially implementation of new methods for the identification of emerging pathogens.

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Phenotypic and Molecular Characterization of a Hospital Outbreak Clonal Lineage of Salmonella enterica Subspecies enterica serovar Mikawasima Containing bla TEM-1B and bla SHV-2 That Emerged on a Neonatal Ward, During the COVID-19 Pandemic

Anita Novak, Mia Dželalija, Ivana Goić-Barišić, Ana Kovačić et autres

Nontyphoid salmonella can cause severe infections in newborns and is therefore declared a pathogen of major health significance at this age. The aim of the study was molecular and antimicrobial characterization of β-lactamase-producing Salmonella Mikawasima outbreak clone on a Neonatal ward, University …

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Mikrobiološka dijagnostika infekcija uzrokovanih bakterijama Ureaplasma urealyticum i Mycoplasma hominis

Tina Kavelj, Anita Novak

Cilj rada: Odrediti učestalost infekcija uzrokovanih M. hominis i U. urealyticum u KBC-u Split od 1.1.2020. do 31.12.2020. te odrediti osjetljivost navedenih izolata na antibiotike u istom periodu.Materijali i metode: Istraživanje je obuhvatilo podatke o pacijentima s dokazanom M. hominis ili U. …

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Molecular characterization of colistin resistance genes in a high-risk ST101/KPC-2 clone of Klebsiella pneumoniae in a University Hospital of Split, Croatia

Žana Rubić, Marko Jelić, Silvija Šoprek, Maja Tarabene et autres

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Microbiome profiling and characterization of virulent and vancomycin-resistant Enterococcus faecium from treated and untreated wastewater, beach water and clinical sources

Mia Dželalija, Marija Kvesić, Anita Novak, Željana Fredotović et autres

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