Dekang Nie

Association of the triglyceride-glucose index with one-year all-cause mortality in patients with spontaneous basal ganglia hemorrhage: a retrospective study

Liyuan Zhang, Zheng Wang, Yi-Xiang Wang, Dekang Nie et autres

BACKGROUND: The triglyceride-glucose (TyG) index is a marker of insulin resistance, and its relationship with the prognosis of patients with spontaneous basal ganglia hemorrhage (SBGH) has not been clearly established. This study aimed to evaluate the relationship between the TyG index and …

cn (code pays fourni par la source)

A modified four-zone classification of the posterior lumbar spinal canal: An anatomical study and clinical application in microchannel surgery

Longfei Shu, Jianwei Zhuo, Feihu Dai, X Li et autres

This study introduces and evaluates a modified four-zone classification of the posterior lumbar spinal canal, assessing its anatomical basis and clinical utility in guiding microchannel surgery. Current minimally invasive lumbar procedures rely predominantly on fluoroscopic imaging of bony landmarks for localization, often …

cn (code pays fourni par la source)

HO-1-modified umbilical cord MSCs alleviate pulmonary arterial hypertension by reducing inflammation and endothelial dysfunction

Riken Chen, Xing Chen, Liang Limei, Hui Li et autres

OBJECTIVE: To evaluate the efficacy of MSCs-HO-1 in pulmonary arterial hypertension (PAH) and explore the underlying mechanisms. METHODS: HO-1 expression and localization in lung tissues and vessels were assessed using spatial transcriptomics and single-cell RNA sequencing analyses of human PAH. MSCs-HO-1 were …

cn (code pays fourni par la source)

MicroRNA‐3651 Facilitates Glioma Progression by Targeting SCN3B and Serves as a Prognostic Indicator

Jun Wang, Yijun Deng, Dekang Nie, Guan Sun et autres

Aim This study is aimed at ascertaining the expression, clinical implications, and cellular functions of miR‐3651 in glioma, as well as its potential target gene, Sodium Voltage-Gated Channel Beta Subunit 3 ( SCN3B ). Methods The expression of serum miR‐3651 was determined …

cn (code pays fourni par la source)

Corrigendum to ‘A dual-functional in situ hydrogel for delivering vitamin E–based lipid nanoparticles to enhance cancer immunotherapy’ [Mater. Today Bio, Volume 35, December 2025, 102289]

Chaozhu Zheng, Dekang Nie, Zhao Wang, Nanjun Li et autres

[This corrects the article DOI: 10.1016/j.mtbio.2025.102289.].

cn (code pays fourni par la source)

A dual-functional in situ hydrogel for delivering vitamin E–based lipid nanoparticles to enhance cancer immunotherapy

Dekang Nie, Zhao Wang, Nanjun Li, Xiaolu Jin et autres

Conventional mRNA lipid nanoparticles often fail to elicit robust antitumor immunity due to their limited capacity to overcome the immunosuppressive tumor microenvironment (TME). Rational design of ionizable lipids with intrinsic bioactivity presents a promising strategy to enhance mRNA-based cancer immunotherapy. Here, we …

cn (code pays fourni par la source)

The microchannel unilateral percutaneous approach to whole exposure bilateral ligamentum flavum in the treatment of lumbar spinal canal stenosis

Dekang Nie, Longfei Shu, Jun Wang, Wei Zeng et autres

cn (code pays fourni par la source)

Targeting inhibition of prognosis-related nicotinamide metabolism genes, including poly (ADP-ribose) polymerase 9 (PARP-9) attenuates glioma progression

Wei Zeng, Haixiao Jiang, Guan Sun, Yunlong Pei et autres

cn, ie (code pays fourni par la source)

Targeting Inhibition of Prognosis-Related Nicotinamide Metabolism Genes, Including Poly (Adp-Ribose) Polymerase 9 (Parp-9) Attenuates Glioma Progression

Dekang Nie, Wei Zeng, Jun Wang, Guan Sun et autres

cn, ie (code pays fourni par la source)

A Magnetic-Responsive Biomimetic Nanosystem Coated with Glioma Stem Cell Membranes Effectively Targets and Eliminates Malignant Gliomas

Song Deng, Dekang Nie, Yue Huang, Yu Yang et autres

Glioblastoma multiforme (GBM) is among the most challenging malignant brain tumors, making the development of new treatment strategies highly necessary. Glioma stem cells (GSCs) markedly contribute to drug resistance, radiation resistance, and tumor recurrence in GBM. The therapeutic potential of nanomaterials targeting …

cn, kr (code pays fourni par la source)

Human umbilical cord derived mesenchymal stem cells overexpressing HO ‐1 attenuate neural injury and enhance functional recovery by inhibiting inflammation in stroke mice

Yu-Sheng Yang, Qianqian Liu, Song Deng, Qian Shao et autres

Abstract Aims The current evidence demonstrates that mesenchymal stem cells (MSCs) hold therapeutic potential for ischemic stroke. However, it remains unclear how changes in the secretion of MSC cytokines following the overexpression of heme oxygenase‐1 (HO‐1) impact excessive inflammatory activation in a …

cn (code pays fourni par la source)

In Situ Attached Photothermal Immunomodulation-Enhanced Nanozyme for the Inhibition of Postoperative Malignant Glioma Recurrence

Dekang Nie, Yuejuan Ling, Wenxin Lv, Qianqian Liu et autres

application that simultaneously serves as photothermal agent and induces immunogenic cell death after GBM surgical resection to enhance the antitumor immunity and delay tumor recurrence. The hemostatic matrix system (Surgiflo@PCN) contains Surgiflo, a multispace structure that can be used to penetrate different …

cn (code pays fourni par la source)