Tessa Kovats

Utility of a Measure of Resilience As a Preoperative Screening Tool to Rule Out Elevated Psychological Symptom Burden

Eugene A. Kim, Rebecca B. Price, Akbota Ayazbekova, Tessa Kovats et autres

BACKGROUND: Psychosocial health is an important predictor of surgical outcomes. Resilience, defined as the ability to "bounce back" from adversity, has been associated with various outcomes, but no consensus exists on measuring resilience in surgical populations. The Connor-Davidson Resilience Scale (CD-RISC), a …

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Ten Years of Intrabronchial Valve Use for Treatment of Persistent Air Leaks

Holden M. Caplan, Harpreet Gill, Tessa Kovats, Ashutosh Sachdeva et autres

BACKGROUND: Persistent air leaks (PALs), nonhealing fistulas between the bronchoalveolar and pleural space existing for at least 5 to 7 days, are challenging to manage. With the humanitarian use device exemption from the United States Food and Drug Administration beginning in 2008, …

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Lack of relationships between ketamine treatment and peripheral neurotrophic and inflammatory factors in a randomized controlled ketamine trial of major depressive disorder

Manivel L. Rengasamy, Benjamin Panny, Zak Hutchinson, Anna L. Marsland et autres

BACKGROUND: Ketamine is a rapid-acting treatment for treatment-resistant depression (TRD), though mechanisms related to ketamine's effects remain unclear. Blood-based neurotrophic and inflammatory factors (NIFs; e.g., brain-derived neurotrophic factor, interleukin-6) have emerged as markers potentially linked to ketamine and ketamine treatment response. METHODS: …

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Exercise induces dynamic changes in intra-articular metabolism and inflammation associated with remodeling of the infrapatellar fat pad in mice

Timothy M. Griffin, Ravi K. Komaravolu, Erika Barboza Prado Lopes, Padmaja Mehta-D’souza et autres

We hypothesized that daily exercise promotes joint health by upregulating anti-inflammatory mediators via adaptive molecular and metabolic changes in the infrapatellar fat pad (IFP). We tested this hypothesis by conducting time-resolved analyses between 1 and 14 days of voluntary wheel running exercise …

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Cross-sectional and longitudinal relationships between complete blood count measures and adolescent suicidal behavior

Manivel L. Rengasamy, Tessa Kovats, Anna Wears, Angela Griffo et autres

Replicable biological predictors are needed to distinguish adolescents at risk for suicide attempts (SA) compared to those at risk for suicidal ideation (SI). Early evidence in adults identifies that complete blood count (CBC) measures may be directly related to suicidal behavior (SB). …

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Linking childhood trauma and cytokine levels in depressed adolescents

Manivel L. Rengasamy, Anna L. Marsland, Lora Lee McClain, Tessa Kovats et autres

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A chicken and egg scenario in psychoneuroimmunology: Bidirectional mechanisms linking cytokines and depression

Manivel L. Rengasamy, Anna L. Marsland, Meredith L. Spada, Kimberly S. Hsiung et autres

Background: Cytokines are an important part of the immune system. Certain cytokines, such as interleukin-6 (IL-6) and tumor necrosis factor alpha (TNFα), have well-described associations with depression. Various mechanisms exist that may explain bidirectional effects of cytokines on depression and vice versa. …

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What’s in a Face? Amygdalar Sensitivity to an Emotional Threatening Faces Task and Transdiagnostic Internalizing Disorder Symptoms in Participants Receiving Attention Bias Modification Training

Manivel L. Rengasamy, Mary L. Woody, Tessa Kovats, Greg J. Siegle et autres

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Longitudinal relationships of cytokines, depression and anhedonia in depressed adolescents

Manivel L. Rengasamy, Anna L. Marsland, Lora Lee McClain, Tessa Kovats et autres

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HSP-27 CAN SIMULTANEOUSLY INDUCE IL-10 AND IL-12 IN BOTH NORMALSʼ AND TRAUMA PATIENTSʼ MONOCYTES (MØ).

Carol Miller, Asit Kumar De, Karen Kodys, Tessa Kovats

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