Chandramani Pathak

Molecular Perspective on Proteases: Regulation of Programmed Cell Death Signaling, Inflammation and Pathological Outcomes

Azharuddin Ansari, Kishu Ranjan, Ashish Kumar, Chandramani Pathak

Proteases are essential enzymes that regulate numerous physiological processes and cellular signaling networks to maintain homeostasis and cellular fate. This regulation is mediated by a group of proteases with the primary function of cleaving peptide bonds, thereby modulating the activity of proteins …

in, us (code pays fourni par la source)

Molecular Perspective of Proteases in Modeling of Cell Death Signaling

Chandramani Pathak, Aafreen Ansari, Ashish Kumar, Kishu Ranjan

Proteases are hallmarks of various physiological processes and cellular signaling net-works that maintain homeostasis and cellular fate. This regulation is particularly medi-ated by carboxypeptidases, cysteine proteases, and metalloproteases, which function by cleaving peptide bonds, thereby modulating the activity of proteins and influencing …

Metabolomics: metabolic signatures in cancer biomarkers

Chandramani Pathak, Foram U. Vaidya, Aafreen Ansari

List of contributors

M.A. Abdelsamed, Md. Khokon Miah Akanda, Aafreen Ansari, Anagha Balakrishnan et autres

Cellular Dynamics of Fas-Associated Death Domain in the Regulation of Cancer and Inflammation

Kishu Ranjan, Chandramani Pathak

Fas-associated death domain (FADD) is an adaptor protein that predominantly transduces the apoptosis signal from the death receptor (DR) to activate caspases, leading to the initiation of apoptotic signaling and the coordinated removal of damaged, infected, or unwanted cells. In addition to …

us, in (code pays fourni par la source)

Cellular Dynamics of Fadd in the Regulation of Cancer and Inflammatory Diseases

Kishu Ranjan, Chandramani Pathak

The Fas associated Death Domain (FADD) is an adaptor protein that predominantly transduces apoptosis signal from death receptor (DR) to activate caspases, leading to the initiation of apoptotic signaling and the coordinated removal of damaged, infected, or unwanted cells. In addition to …

us, in (code pays fourni par la source)

Insights of Endocytosis Signaling in Health and Disease

Chandramani Pathak, Foram U. Vaidya, Bhargav N. Waghela, Pradip Kumar Jaiswara et autres

Endocytosis in mammalian cells is a fundamental cellular machinery that regulates vital physiological processes, such as the absorption of metabolites, release of neurotransmitters, uptake of hormone cellular defense, and delivery of biomolecules across the plasma membrane. A remarkable characteristic of the endocytic …

in, us (code pays fourni par la source)

Insights of Endocytosis Signaling in Health and Disease

Chandramani Pathak, Foram U. Vaidya, Bhargav N. Waghela, Pradeep Kumar Jaiswara et autres

Endocytosis in mammalian cells is a fundamental cellular machinery that regulates vital physiological processes, such as the absorption of metabolites, release of neurotransmitters, hormonal secretion, cellular defense, and delivery of biomolecules across the plasma membrane. A remarkable characteristic of the endocytic machinery …

in, us (code pays fourni par la source)

Structural transitions in mixed Phosphatidylcholine/Pluronic micellar systems and their in vitro therapeutic evaluation for poorly water-soluble drug

Hemil S. Patel, Sofiya J. Shaikh, Debes Ray, Vinod Kumar Aswal et autres

in, ir (code pays fourni par la source)

Phosphodiesterase 5 inhibitor sildenafil potentiates the antitumor activity of cisplatin by ROS-mediated apoptosis: a role of deregulated glucose metabolism

Shiv Govind Rawat, Rajan Kumar Tiwari, Pradip Kumar Jaiswara, Vishal Kumar Gupta et autres

in (code pays fourni par la source)

Higher BCG‐induced trained immunity prevalence predicts protection from COVID‐19: Implications for ongoing BCG trials

Samer Singh, Dhiraj Kishore, Rakesh Kumar Singh, Chandramani Pathak et autres

Abstract Endeavors to identify potentially protective variables for COVID‐19 impact on certain populations have remained a priority. Multiple attempts have been made to attribute the reduced COVID‐19 impact on populations to their Bacillus–Calmette–Guérin (BCG) vaccination coverage ignoring the fact that the effect …

in, us (code pays fourni par la source)

Advanced Glycation End Products-Mediated Oxidative Stress and Regulated Cell Death Signaling in Cancer

Chandramani Pathak, Foram U. Vaidya, Bhargav N. Waghela, Abu Sufiyan Chhipa et autres

in, us (code pays fourni par la source)