Lena Palmberg

FN-silk membrane enables alveologenesis processes and self-organization of the H441 epithelial cell line into native-like alveolar morphology

Savvini Gkouma, Linnéa Påvénius, Linnéa Gustafsson, Christos Tasiopoulos et autres

In vitro alveolar-capillary models based on co-culturing the alveolar epithelial cell line H441 and primary pulmonary microvascular endothelial cells (HPMEC) are a widely used platform for evaluating the function of the alveolar barrier. However, the relatively thick synthetic membranes that are used …

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The metabolic profile of Extracellular Vesicles identifies and separates patients with Sarcoidosis and Anti-Synthetase Syndrome

Loïc Steiner, Maria Eldh, Christina Samakovli, Elga Bernardo Bandeira De Melo et autres

Abstract Sarcoidosis is a multisystem disorder that primarily affects the lungs and is characterizedby granulomatous inflammation. However, much of the underlying disease mechanisms remain poorly understood. Extracellular vesicles (EVs) are small membrane-bound particles released by all cells and carry various cargos including …

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Epithelial effects of exposure to e-cigarettes alone or in combination with cigarette smoke using multicellular lung mucosa models

Shanzina Iasmin Sompa, Swapna Upadhyay, Koustav Ganguly, Anna Bergström et autres

Pulmonary molecular toxicity data on electronic (e)-cigarettes, alone or in combination with cigarette smoke, remain limited. We developed air-liquid interface bronchial and alveolar lung mucosa models using primary human bronchial epithelial cells and human type II alveolar epithelial cell lines, respectively. Models …

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Investigating the exhaled lipid biomarkers among e-cigarette users compared to non-smokers

Shanzina Iasmin Sompa, Per Larsson, Jie Ji, Bengt Sjögren et autres

The Particle in Exhaled Air (PExA) method provides a non-invasive way to evaluate how electronic (e)-cigarette aerosols affect the small airways by providing a sample of their lining fluid. This study explored for the first time the changes in the lipid profiles …

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Additional file 2 of Investigating the exhaled lipid biomarkers among e-cigarette users compared to non-smokers

Shanzina Iasmin Sompa, Per Larsson, J Ji, Bengt Sjögren et autres

Additional file 2: Figure S1. A flow chart illustrating the inclusion of the participants.

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Additional file 2 of Investigating the exhaled lipid biomarkers among e-cigarette users compared to non-smokers

Shanzina Iasmin Sompa, Per Larsson, J Ji, Bengt Sjögren et autres

Additional file 2: Figure S1. A flow chart illustrating the inclusion of the participants.

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Household Air Pollution and Respiratory Outcomes Among Women Using Biomass Fuel for Cooking in India: Evidence Generation for Policy Action

P A Mahesh, A. S. Praveena, Mandya Venkateshmurthy Greeshma, Vikram Patil et autres

Background The world′s largest intervention program to provide affordable cleaner cooking fuel (liquefied petroleum gas [LPG]) to women living in poor households was launched in 2016 in India with the aim to mitigate household air pollution (HAP). Globally, it was estimated that …

Different Susceptibility to Particulate Matter Exposure within the Respiratory Tract

Lovisa Jonason, Jonas Sjöblom, Monica Kåredal, Lena Palmberg et autres

Air pollution contributes to millions of premature deaths annually. Inhaled particulate matter (PM) can deposit on the airway epithelium, triggering oxidative stress and inflammation. Long-term exposure to even low levels of PM has been linked to severity in chronic lung disorders as …

Similar global transcription patterns in mouse lung tissue following pulmonary exposure to renewable and conventional diesel engine exhaust particles

Anda R. Gliga, Sarah McCarrick, Vilhelm Malmborg, Pekka Kohonen et autres

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New nicotine and tobacco products and risk of major diseases: A review of the scientific evidence

Sofia Carlsson, Anna Bergström, Kristian Dreij, Koustav Ganguly et autres

The use of new tobacco and nicotine products, including e-cigarettes, heated tobacco products (HTPs) and tobacco-free snus (white snus), is rising, especially among adolescents and young adults. However, evidence on their long-term health effects is limited. This review assesses current knowledge on …

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Potential pulmonary toxic effects of Martian dust simulant

Jie Ji, Jasmine Rita Petriglieri, Francesco Turci, Shanzina Iasmin Sompa et autres

Human exploration of the Moon and Mars will inevitably result in exposure to extraterrestrial dust. We investigated the potential pulmonary toxicity of JSC Mars-1(Martian dust simulant, respirable diameter 1.45 μm) using an advanced multicellular lung mucosa model with dust applied apically to …

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Reply to “matters arising: “local and systemic effects in e-cigarette users compared to cigarette smokers, dual users, and non-smokers”

Shanzina Iasmin Sompa, Lena Palmberg

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