Koustav Ganguly

Household Air Pollution and Respiratory Outcomes Among Women Using Biomass Fuel for Cooking in India: Evidence Generation for Policy Action

P A Mahesh, A. S. Praveena, Mandya Venkateshmurthy Greeshma, Vikram Patil et autres

Background The world′s largest intervention program to provide affordable cleaner cooking fuel (liquefied petroleum gas [LPG]) to women living in poor households was launched in 2016 in India with the aim to mitigate household air pollution (HAP). Globally, it was estimated that …

New nicotine and tobacco products and risk of major diseases: A review of the scientific evidence

Sofia Carlsson, Anna Bergström, Kristian Dreij, Koustav Ganguly et autres

The use of new tobacco and nicotine products, including e-cigarettes, heated tobacco products (HTPs) and tobacco-free snus (white snus), is rising, especially among adolescents and young adults. However, evidence on their long-term health effects is limited. This review assesses current knowledge on …

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Local and systemic effects in e-cigarette users compared to cigarette smokers, dual users, and non-smokers

Shanzina Iasmin Sompa, Jie Ji, Mizanur Rahman, Bengt Sjögren et autres

BACKGROUND: The use of electronic (e)-cigarettes in the long term has been associated with an increased risk of respiratory diseases. Dual use of e-cigarettes and traditional cigarettes may increase these risks even more due to the combined exposure effects of these products. …

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Household Air Pollution and Respiratory Outcomes Among Women Using Biomass Fuel for Cooking in India

Koustav Ganguly, A. S. Praveena, Mandya Venkateshmurthy Greeshma, Vikram Patil et autres

Abstract Rationale: World's largest intervention program to provide affordable cleaner cooking fuel (liquefied petroleum gas/LPG) to women living in poor households was launched in 2016 in India with the aim to mitigate household air pollution (HAP). Globally, it was estimated that 1.8 …

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Serum Raman Spectroscopy – An exploratory study for detection of chronic obstructive pulmonary disease

Gautam Sharma, Priyanka Jadhav, Debarghya Pratim Gupta, P A Mahesh et autres

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Meta-Analysis and DIA-MS-Based Proteomic Investigation of COPD Patients and Asymptomatic Smokers in the Indian Population

Gautam Sharma, Debarghya Pratim Gupta, Koustav Ganguly, P A Mahesh et autres

Chronic obstructive pulmonary disease (COPD) is India’s second largest cause of death and is largely caused by smoking. Asymptomatic smokers develop COPD due to genetic, environmental, and molecular variables, making early screening crucial. Data-independent acquisition mass spectrometry (DIA-MS) based-proteomics offers an unbiased …

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Contrasting effects of intracellular and extracellular human PCSK9 on inflammation, lipid alteration and cell death

Aram Ghalali, Fahd Alhamdan, Swapna Upadhyay, Koustav Ganguly et autres

Proprotein convertase subtilisin/kexin type 9 (PCSK9) is one of the major regulators of low-density lipoprotein receptor (LDLR). Information on role and regulation of PCSK9 in lung is very limited. Our study focuses on understanding the role and regulation of PCSK9 in the …

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Contrasting Effects of Endogenous and extracellular PCSK9 on Inflammation, Lipid alteration and Cell death.

Aram Ghalali, Fahd Alhamdan, Swapna Upadhyay, Koustav Ganguly et autres

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Assessment of wood smoke induced pulmonary toxicity in normal- and chronic bronchitis-like bronchial and alveolar lung mucosa models at air–liquid interface

Swapna Upadhyay, Mizanur Rahman, Selina Rinaldi, Jeremy P. Koelmel et autres

BACKGROUND: Chronic obstructive pulmonary disease (COPD) has the highest increased risk due to household air pollution arising from biomass fuel burning. However, knowledge on COPD patho-mechanisms is mainly limited to tobacco smoke exposure. In this study, a repeated direct wood smoke (WS) …

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Respiratory Outcomes Among Women Using Biomass Cooking Fuel in India: Evidence Generation for Policy Action

P A Mahesh, Praveena A. S, Mandya Venkateshmurthy Greeshma, Vikram Patil et autres

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Lipid from electronic cigarette-aerosol both with and without nicotine induced pro-inflammatory macrophage polarization and disrupted phagocytosis

Mizanur Rahman, Shanzina Iasmin Sompa, Micol Introna, Swapna Upadhyay et autres

Clinical cases and experimental evidence revealed that electronic cigarettes (ECIG) induce serious adverse health effects, but underlying mechanisms remain to be fully uncovered. Based on recent exploratory evidence, investigating the effects of ECIG on macrophages can broadly define potential mechanisms by focusing …

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The Validity of the ROX Index and APACHE II in Predicting Early, Late, and Non-Responses to Non-Invasive Ventilation in Patients with COVID-19 in a Low-Resource Setting

Sumalatha Arunachala, Ashwaghosha Parthasarathi, Chetak Kadabasal Basavaraj, Mohammed Kaleem Ullah et autres

The use of the Ratio of Oxygen Saturation (ROX) index to predict the success of high-flow nasal oxygenation (HFNO) is well established. The ROX can also predict the need for intubation, mortality, and is easier to calculate compared with APACHE II. In …

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