Christiane Pfeiffer

Treatment of systemic sclerosis–associated pulmonary hypertension with and without interstitial lung disease and its impact on survival: a large cohort study of the German network for systemic sclerosis

Marc Schmalzing, Pia Moinzadeh, Jithmi Weliwitage, Joerg Henes et autres

OBJECTIVES: This study aimed to analyse survival in SS-associated pulmonary hypertension (SSc-PH) patients with or without interstitial lung disease (ILD) stratified by PH monotherapy and PH combination therapy, respectively. METHODS: Among the 6003 patients registered with the German Network for Systemic Sclerosis …

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Resminostat for maintenance treatment in patients with advanced-stage mycosis fungoides or Sézary syndrome: a multicentre, double-blind, randomised, placebo-controlled, phase 2 trial

Rudolf Stadler, Rudolf Stadler, Pietro Quaglino, F J Sherida H Woei-A-Jin et autres

de, by, be, ch, gr, es, at, jp, gb, fr, us, it, hu, pl (code pays fourni par la source)

A phase 2b basket trial approach to treat multiple rare and fibrotic skin diseases

Sebastian Volc, Peter Martus, Matthias Schefzyk, Claudia Günther et autres

Fibrotic skin diseases are rare, chronic, and often debilitating conditions characterized by excessive extracellular matrix deposition, leading to tissue scarring and functional impairment. Despite their severity, diseases-such as lichen sclerosus et atrophicus (LSA), frontal fibrosing alopecia (FFA), radiation-induced skin fibrosis (RISF), eosinophilic …

de (code pays fourni par la source)

Multi-Omics Molecular Profiling Enables Rapid Diagnosis of Erythrodermic Skin Diseases

Pia‐Charlotte Stadler, Katrin Kerl-French, Georg Wallmann, Lucas Diedrich et autres

Summary Erythroderma is an acute and potentially life-threatening inflammatory condition characterized by redness and scaling of > 90% of the skin. Its treatment is challenging because various underlying skin diseases can cause erythroderma and are difficult to distinguish. Here, we performed in-depth …

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POS0834 TREATMENT AND DISEASE SEVERITY OF SSc-ASSOCIATED PULMONARY HYPERTENSION WITH AND WITHOUT INTERSTITIAL LUNG DISEASE: A LARGE COHORT STUDY OF THE GERMAN NETWORK FOR SYSTEMIC SCLEROSIS

Marc Schmalzing, Pia Moinzadeh, Jithmi Weliwitage, Gabriela Riemekasten et autres

de (code pays fourni par la source)

Skleromyxödem

Cord H. Sunderkötter, Tom Bruns, Christiane Pfeiffer

de (code pays fourni par la source)

Differenzialdiagnosen sklerosierender Dermatosen: Scleroedema adultorum Buschke

Christiane Pfeiffer, Cord H. Sunderkötter

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Efficacy and safety of adjuvant immunoadsorption in pemphigus vulgaris and pemphigus foliaceus (IA-Pem Study): a multicentre randomized controlled trial

Nina van Beek, Rüdiger Eming, Alexander Reuß, Detlef Zillikens et autres

BACKGROUND: Pemphigus vulgaris (PV) and pemphigus foliaceus (PF) are potentially life-threatening autoimmune blistering diseases. Treatment is based on long-term immunosuppression with high doses of glucocorticosteroids in combination with potentially corticosteroid-sparing agents and/or rituximab. Immunoadsorption (IA) has emerged as a fast-acting adjuvant treatment …

de (code pays fourni par la source)

Impact of Systemic Sclerosis-Associated Interstitial Lung Disease With and Without Pulmonary Hypertension on Survival

Pia Moinzadeh, Francesco Bonella, Max Oberste, Jithmi Weliwitage et autres

BACKGROUND: Pulmonary involvement is the leading cause of death in systemic sclerosis (SSc) and may manifest as interstitial lung disease (ILD), pulmonary arterial hypertension (PAH), or in combination of both (ILD with pulmonary hypertension [ILD-PH]). The aim of this analysis was to …

de (code pays fourni par la source)

Anti-acid therapy in SSc-associated interstitial lung disease: long-term outcomes from the German Network for Systemic Sclerosis

Michael Kreuter, Francesco Bonella, Norbert Blank, Gabriela Riemekasten et autres

OBJECTIVES: Gastroesophageal reflux disease (GERD) occurs frequently in patients with SSc. We investigated whether the presence of GERD and/or the use of anti-acid therapy, specifically proton-pump inhibitors (PPIs), are associated with long-term outcomes, especially in SSc-associated interstitial lung disease (SSc-ILD). METHODS: We …

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Autologous hematopoietic stem cell transplantation improves long-term survival—data from a national registry

Norbert Blank, Marc Schmalzing, Pia Moinzadeh, Max Oberste et autres

BACKGROUND: Current recommendations on the management of systemic sclerosis (SSc) suggest that autologous hematopoietic stem cell therapy (HSCT) can be a rescue therapy for patients with rapidly progressive SSc. OBJECTIVES: To assess the safety and efficacy of HSCT for patients with SSc …

de (code pays fourni par la source)

Autologous hematopoietic stem cell transplantation improves long term survival – data from a national registry

Norbert Blank, Marc Schmalzing, Pia Moinzadeh, Max Oberste et autres

Abstract BackgroundCurrent recommendations on the management of systemic sclerosis (SSc) suggest that autologous hematopoietic stem cell therapy (HSCT) can be a rescue therapy for patients with rapidly progressive SSc. Objectives To assess safety and efficacy of HSCT for patients with SSc and …

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