Jianmin Ling

Hexokinase 2 deficiency protects against sepsis-associated lung injury via suppressing the NF-κB signaling pathway

Jianmin Ling, J Lu, Guangyang Bai, Minghao Fang et autres

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Advances in lymphoma biomarkers research based on proteomics technology (Review)

Jianmin Ling, Zhao Li, Lintao Bi

Lymphoma is a common malignancy characterized by diverse pathological types and marked heterogeneity. Distinct subtypes of lymphomas are markedly different in their clinical manifestations, treatment approaches and prognostic outcomes. With the rapid development of molecular biology techniques, antitumor research has stepped into …

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Functional, Pulmonary, Psychological and Cognitive Status Up to 12 Months Post-ICU Discharge in COVID-19 Patients: A Preliminary Analysis of the International Aftercor Study

Karin S. Wildi, Alessandra Bandera, Denise Battaglini, Silvia Bertagnolio et autres

Abstract Long-term sequelae associated with COVID-19 are currently poorly defined, specifically in patients who have been discharged from intensive care units. We hypothesized that functional and pulmonary capacity, as well as mental health and cognitive function, would remain outside the normal range …

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(−)‐Epicatechin Rescues Memory Deficits by Activation of Autophagy in a Mouse Model of Tauopathies

Yanqing Wu, Ting Li, Xingjun Jiang, Jianmin Ling et autres

In tauopathies, defects in autophagy-lysosomal protein degradation are thought to contribute to the abnormal accumulation of aggregated tau. Recent studies have shown that (-)-Epicatechin (Epi), a dietary flavonoid belonging to the flavan-3-ol subgroup, improves blood flow, modulates metabolic profiles, and prevents oxidative …

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Differences between Primary Central Nervous System Diffuse Large B-Cell Lymphoma and Intra-Lymph Node Diffuse Large B-Cell Lymphoma Based on Proteomic Research

Xiangyi Guo, Lintao Bi, Di Zhou, Jianmin Ling

Background: Primary central nervous system lymphoma(PCNSL) is a rare extranodal lymphoma with limited lesions. About 95% or more of the patients have a pathologic staging of diffuse large B-cell lymphoma(DLBCL), which is characterized by highly aggressive, rapid progression, and poor prognosis, and …

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The role of heat shock protein B8 in neuronal protection against oxidative stress and mitochondrial dysfunction: A literature review

Yanqing Wu, Feng Xiong, Jianmin Ling

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Adiponectin receptor agonist AdipoRon alleviates memory impairment in the hippocampus of septic mice

Guangyang Bai, Jianmin Ling, Jun Feng Lu, Minghao Fang et autres

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4-PBA exerts brain-protective effects against sepsis-associated encephalopathy in a mouse model of sepsis

Feng Xiong, Cailin Wang, Jun Lu, Guangyang Bai et autres

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Investigating the Drug Resistance Mechanisms of Refractory Diffuse Large B-Cell Lymphoma Based on Proteomic Research

Lintao Bi, Jianmin Ling, Di Zhou, Li Zhao

Diffuse large B-cell lymphoma (DLBCL) is the most common histological subtype of non-Hodgkin's lymphoma, more than half of the patients of which can achieve complete remission or even be cured with multidrug immunochemotherapy regimen(R-CHOP). However, for patients with relapsed or refractory DLBCL, …

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Melatonin Attenuates Sepsis-Induced Acute Lung Injury via Inhibiting Excessive Mitophagy

Jianmin Ling, Shanshan Yu, Feng Xiong, Tingting Xu et autres

Background: Epidemiological studies have indicated that lung injury is a frequent complication of sepsis. Mitophagy is vital to multiple pathological processes and diseases; however, its influence on sepsis-induced acute lung injury remains elusive. Melatonin has multiple antioxidant action and anti-inflammatory effects, including …

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Three subtypes of postoperative ARDS that showing different outcomes and responses to mechanical ventilation and fluid management: A machine learning and latent profile analysis

Jianmin Ling, Han Liu, Dongge Yu, Zhaohua Wang et autres

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HSPB8 up-regulation alleviates cognitive dysfunction in a mouse model of sepsis-associated encephalopathy

Jianmin Ling, Shanshan Yu, Feng Xiong, Shusheng Li

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