Laura Spence

Nurturing the Future Part 1: Holistic Wellbeing and Student Midwife Retention

Zoe Coe, Laura Spence, Sam Jniah, Emilie Edwards

This article, first in a four part series, addresses the student attrition crisis by advocating for a transition from individual resilience to systemic sustainability. By reframing support through scaffolded learning, it shifts the onus of professional success from the student to the …

Tranexamic acid versus placebo to prevent bleeding in patients with haematological malignancies and severe thrombocytopenia (TREATT): a randomised, double-blind, parallel, phase 3 superiority trial

Lise J Estcourt, Zoe McQuilten, Peter Bardy, Merrole Cole‐Sinclair et autres

What It’s Like Being A Midwife With Attention Deficit Hyperactivity Disorder

Laura Spence

Some women with attention deficit hyperactivity disorder (ADHD) may go their entire lives without receiving a diagnosis. This diagnosis gap exists in part because the disorder was once assumed to mostly afflict men but also because women typically exhibit less socially disruptive …

ChemInform Abstract: Direct Access to Functionalized Benzotropones, Azepanes, and Piperidines by Reductive Cross‐Coupling of α‐Bromo Enones with α‐Bromo Enamides.

Timothy K. Beng, Kayla Sincavage, Ann Wens V. Silaire, Amir Alwali et autres

Abstract under cobalt catalysis

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ChemInform Abstract: Cobalt‐Catalyzed Arylation and Alkenylation of α‐Bromo Eneformamides and Enecarbamates by Cross‐Coupling with Organic Bromides: Application to the Synthesis of Functionalized Piperidines and Azepanes.

Daniel P. Bassler, Amir Alwali, Laura Spence, Oliver Beale et autres

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ChemInform Abstract: Expedient Access to α,β‐Difunctionalized Azepenes Using α‐Halo Eneformamides: Application to the One‐Pot Synthesis of 2‐Benzazepanes.

Daniel P. Bassler, Laura Spence, Amir Alwali, Oliver Beale et autres

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Cobalt-catalyzed arylation and alkenylation of alpha-bromo eneformamides and enecarbamates by cross-coupling with organic bromides: Application to the synthesis of functionalized piperidines and azepanes

Daniel P. Bassler, Amir Alwali, Laura Spence, Oliver Beale et autres

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Expedient access to α,β-difunctionalized azepenes using α-halo eneformamides: application to the one-pot synthesis of 2-benzazepanes

Daniel P. Bassler, Laura Spence, Amir Alwali, Oliver Beale et autres

The regioselective synthesis of α,β-difunctionalized (alkenyl, aryl, sulfonyl, allyl, or alkynyl) azepenes has been accomplished through α-halo eneformamides. A successful implementation of the vicinal functionalization strategy has led to a one-pot synthesis of 2-benzazepanes whose benzenoid portion is highly functionalized.

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Direct access to functionalized benzotropones, azepanes, and piperidines by reductive cross-coupling of α-bromo enones with α-bromo enamides

Timothy K. Beng, Kayla Sincavage, Ann Wens V. Silaire, Amir Alwali et autres

The synthesis of functionalized azepenes and piperidines bearing an α-cycloheptenone or benzotropone derivative has been accomplished through direct reductive cross-coupling of α-bromo eneformamides or enecarbamates with highly versatile α-bromo benzotropone derivatives, under cobalt catalysis. The coupling products have been further elaborated to …

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Connecting the dots: monocyte/DC and NK subsets in human peripheral blood

Venetia Bigley, Laura Spence, Matthew Collin

To the editor: A recent paper in Blood reported that lineage (CD3/14/19)–negative CD56+ mononuclear cells in human peripheral blood contain 2 populations: bona fide CD7+ natural killer (NK) cells and CD7− monocyte/dendritic cells (DCs).[1][1] Whereas this study delivers a valuable improvement

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A retrospective study of alemtuzumab level, t-cell chimerism and graft-versus-host disease using intermediate dose alemtuzumab for matched related and matched unrelated reduced-intensity transplantation

Tom C Naunton Morgan, Wei Cope, Andrew Charlton‐Perez, Laura Spence et autres

A Retrospective Study of Alemtuzumab Level, T Cell Chimerism and Graft Versus Host Disease Using Intermediate Dose Alemtuzumab for Matched Related and Matched Unrelated Reduced Intensity Transplantation.

Andrew Charlton, Laura Spence, Venetia Bigley, Natasha Groves et autres

Abstract Abstract 3333 Poster Board III-221 Alemtuzumab (CAMPATH 1H) is a well established agent for effecting in vivo T cell depletion and prevention of GVHD in reduced intensity transplants. Many studies indicate that full dose alemtuzumab (100mg in 5 daily doses of …

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